Compound Summary
H-8 dihydrochloride
Compound Information
H-8 dihydrochloride
Compound Name: | H-8 dihydrochloride |
Compound CID: | 150584 |
Synonyms: | H-8 dihydrochloride 113276-94-1 H-8, Dihydrochloride H8 dihydrochloride N-2-(Methylamino)ethyl-5-isoquinolinesulfonamide dihydrochloride More... |
Iupac Name: | N-[2-(methylamino)ethyl]isoquinoline-5-sulfonamide;dihydrochloride |
InChI: | InChI=1S/C12H15N3O2S.2ClH/c1-13-7-8-15-18(16,17)12-4-2-3-10-9-14-6-5-11(10)12;;/h2-6,9,13,15H,7-8H2,1H3;2*1H |
InChIKey: | RJJLZYZEVNCZIW-UHFFFAOYSA-N |
Canonical Smiles: | CNCCNS(=O)(=O)C1=CC=CC2=C1C=CN=C2.Cl.Cl |
Isomeric Smiles: | CNCCNS(=O)(=O)C1=CC=CC2=C1C=CN=C2.Cl.Cl |
Molecular Weight: | 338.3 |
Molecular Formula: | C12H17Cl2N3O2S |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
H-8 dihydrochloride
Molecular Weight: | 338.3 |
Molecular Formula: | C12H17Cl2N3O2S |
Hydrogen Bond Donor Count: | 4 |
Hydrogen Bond Acceptor Count: | 5 |
Rotatable Bond Count: | 5 |
Heavy Atom Count: | 20 |
Complexity: | 353 |
Synonyms
H-8 dihydrochloride
| H-8 dihydrochloride | H-8 dihydrochloride |
|---|---|
H-8 dihydrochloride |
113276-94-1 |
H-8, Dihydrochloride |
H8 dihydrochloride |
N-2-(Methylamino)ethyl-5-isoquinolinesulfonamide dihydrochloride |
N-(2-(Methylamino)ethyl)isoquinoline-5-sulfonamide dihydrochloride |
C12H15N3O2S.2HCl |
N-(2-(Methylamino)ethyl)-5-isoquinolinesulfonamide dihydrochloride |
H8 |
N-2-(methylamino)ethylisoquinoline-5-sulfonamide;dihydrochloride |
H 8 dihydrochloride |
H-8 (hydrochloride) |
BMK1-D12 |
SCHEMBL1165266 |
CHEMBL1395058 |
N-2-(Methylamino)ethyl-5-isoquinolinesulfonamide, 2HCl |
DTXSID901017099 |
HMS3229F07 |
N-2-(Methylamino)ethyl-5-isoquinolinesulfonamide hydrochloride |
Tox21_500822 |
1782AH |
5-Isoquinolinesulfonamide, N-(2-(methylamino)ethyl)-, dihydrochloride |
MFCD00036962 |
AKOS022180587 |
H-8 dihydrochloride, >98% (HPLC) |
CCG-222126 |
LP00822 |
MCULE-9323665464 |
NCGC00094153-01 |
NCGC00261507-01 |
DB-041164 |
EU-0100822 |
FT-0642772 |
M 9656 |
A803036 |
SR-01000075502 |
SR-01000075502-1 |
N-2-(methylamino)ethylisoquinoline-5-sulfonamidedihydrochloride |
5-Isoquinolinesulfonamide,N-2-(methylamino)ethyl-, hydrochloride (1:2) |
Experimental Data
H-8 dihydrochloride
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33.000000000000000 | umol/L | 7.000000000000000 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
H-8 dihydrochloride
Statistics Data
H-8 dihydrochloride
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 7.000000000000000 | 1 | 1 |
Statistics Data Visualization
H-8 dihydrochloride
