Compound Summary
Gabazine
Compound Information
Gabazine
Compound Name: | Gabazine |
Compound CID: | 107896 |
Synonyms: | Gabazine Gabazine free base 105538-73-6 CHEBI:34968 SR95531 More... |
Iupac Name: | 4-[6-imino-3-(4-methoxyphenyl)pyridazin-1-yl]butanoic acid |
InChI: | InChI=1S/C15H17N3O3/c1-21-12-6-4-11(5-7-12)13-8-9-14(16)18(17-13)10-2-3-15(19)20/h4-9,16H,2-3,10H2,1H3,(H,19,20) |
InChIKey: | ACVGNKYJVGNLIL-UHFFFAOYSA-N |
Canonical Smiles: | COC1=CC=C(C=C1)C2=NN(C(=N)C=C2)CCCC(=O)O |
Isomeric Smiles: | COC1=CC=C(C=C1)C2=NN(C(=N)C=C2)CCCC(=O)O |
Molecular Weight: | 287.31 |
Molecular Formula: | C15H17N3O3 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
Gabazine
Molecular Weight: | 287.31 |
Molecular Formula: | C15H17N3O3 |
Hydrogen Bond Donor Count: | 2 |
Hydrogen Bond Acceptor Count: | 5 |
Rotatable Bond Count: | 6 |
Heavy Atom Count: | 21 |
Complexity: | 451 |
Synonyms
Gabazine
| Gabazine | Gabazine |
|---|---|
Gabazine |
Gabazine free base |
105538-73-6 |
CHEBI:34968 |
SR95531 |
C13796 |
UNII-L45297DIU1 |
4-(6-imino-3-(4-methoxyphenyl)pyridazin-1(6H)-yl)butanoic acid |
Tocris-1262 |
Prestwick0_000443 |
Prestwick1_000443 |
Prestwick2_000443 |
CHEMBL32503 |
J331.170H |
4-6-imino-3-(4-methoxyphenyl)pyridazin-1-ylbutanoic acid |
1(6H)-Pyridazinebutanoic acid, 6-imino-3-(4-methoxyphenyl)- |
L45297DIU1 |
6-imino-3-(4-methoxyphenyl)-1(6h)-pyridazinebutanoic acid |
1,6-Dihydro-6-imino-3-(4-methoxyphenyl)-1-pyridazinebutanoic acid |
4-(6-Imino-3-(4-methoxyphenyl)pyridazin-1-yl)butanoic acid |
SR 95531 |
4-6-imino-3-(4-methoxyphenyl)-1,6-dihydropyridazin-1-ylbutanoic acid |
3Hgabazine |
2-(3-Carboxypropyl)-3-amino-6-(4-methoxyphenyl)pyridazinium |
Biomol-NT_000259 |
SPBio_002425 |
BPBio1_000771 |
GTPL4083 |
GTPL4197 |
SCHEMBL5529434 |
DTXSID20276043 |
4-(6-Imino-3-(4-methoxyphenyl)-1(6H)-pyridazinyl)butanoic acid |
BCP33110 |
ZINC2559949 |
BDBM50001572 |
PDSP1_001604 |
PDSP2_001588 |
ZINC02559949 |
AKOS030254307 |
NCGC00025088-01 |
NCGC00025088-02 |
NCGC00025088-03 |
FT-0668923 |
G-215 |
J-001443 |
BRD-K79905821-001-01-6 |
Q27894364 |
SR95531; SR 95531; SR-95531 |
4-6-imino-3-(4-methoxyphenyl)pyridazin-1-ylbutanoic acid. |
4-6-Imino-3-(4-methoxy-phenyl)-6H-pyridazin-1-yl-butyric acid |
(gabazine)4-6-Imino-3-(4-methoxy-phenyl)-6H-pyridazin-1-yl-butyric acid |
4-6-Imino-3-(4-methoxy-phenyl)-6H-pyridazin-1-yl-butyric acid (gabazine or SR-95331) |
4-6-Imino-3-(4-methoxy-phenyl)-6H-pyridazin-1-yl-butyric acid(Gabazine) |
Experimental Data
Gabazine
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33.000000000000000 | umol/L | -7.000000000000000 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
Gabazine
Statistics Data
Gabazine
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -7.000000000000000 | 1 | 1 |
Statistics Data Visualization
Gabazine
