Compound Summary
GR 46611
Compound Information
GR 46611
Compound Name: | GR 46611 |
Compound CID: | 6160690 |
Synonyms: | GR 46611 185259-85-2 3-3-(2-Dimethylaminoethyl)-1H-indol-5-yl-N-(4-methoxybenzyl)acrylamide GR46611 GR 4661 More... |
Iupac Name: | (E)-3-[3-[2-(dimethylamino)ethyl]-1H-indol-5-yl]-N-[(4-methoxyphenyl)methyl]prop-2-enamide |
InChI: | InChI=1S/C23H27N3O2/c1-26(2)13-12-19-16-24-22-10-6-17(14-21(19)22)7-11-23(27)25-15-18-4-8-20(28-3)9-5-18/h4-11,14,16,24H,12-13,15H2,1-3H3,(H,25,27)/b11-7+ |
InChIKey: | LBVZWEWTNUDWNS-YRNVUSSQSA-N |
Canonical Smiles: | CN(C)CCC1=CNC2=C1C=C(C=C2)C=CC(=O)NCC3=CC=C(C=C3)OC |
Isomeric Smiles: | CN(C)CCC1=CNC2=C1C=C(C=C2)/C=C/C(=O)NCC3=CC=C(C=C3)OC |
Molecular Weight: | 377.5 |
Molecular Formula: | C23H27N3O2 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
GR 46611
Molecular Weight: | 377.5 |
Molecular Formula: | C23H27N3O2 |
Hydrogen Bond Donor Count: | 2 |
Hydrogen Bond Acceptor Count: | 3 |
Rotatable Bond Count: | 8 |
Heavy Atom Count: | 28 |
Complexity: | 514 |
Synonyms
GR 46611
| GR 46611 | GR 46611 |
|---|---|
GR 46611 |
185259-85-2 |
3-3-(2-Dimethylaminoethyl)-1H-indol-5-yl-N-(4-methoxybenzyl)acrylamide |
GR46611 |
GR 4661 |
CHEMBL344127 |
(E)-3-3-2-(dimethylamino)ethyl-1H-indol-5-yl-N-(4-methoxyphenyl)methylprop-2-enamide |
SR-01000076206 |
3-(3-(2-Dimethylaminoethyl)-1H-indol-5-yl)-N-(4-methoxybenzyl)acrylamide |
Lopac0_000069 |
MLS001056583 |
SCHEMBL4784832 |
CHEBI:93195 |
(E)-3-(3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)-N-(4-methoxybenzyl)acrylamide |
HMS2233M08 |
HMS3260M19 |
HMS3411P15 |
HMS3675P15 |
ZINC840177 |
Tox21_500069 |
BDBM50054764 |
PDSP1_001395 |
PDSP2_001379 |
AKOS024458670 |
CCG-204164 |
GR-4661 |
LP00069 |
SDCCGSBI-0050057.P002 |
NCGC00024831-02 |
NCGC00024831-03 |
NCGC00024831-04 |
NCGC00024831-05 |
NCGC00260754-01 |
SMR000326973 |
EU-0100069 |
G 8543 |
SR-01000076206-1 |
SR-01000076206-3 |
2-METHYL-5-(PIPERIDINOSULFONYL)-3-FUROICACID |
BRD-K68190965-001-01-4 |
3-3-(2-dimethylaminoethyl)-1h-indol-5-yl-n-(4-methoxybenzyl) acrylamide |
(E)-3-3-(2-Dimethylamino-ethyl)-1H-indol-5-yl-N-(4-methoxy-benzyl)-acrylamide |
2-Propenamide, 3-(3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)-N-((4-methoxyphenyl)methyl)- |
3-(3-(2-(dimethylamino)ethyl)-1h-indol-5-yl)-n-(4-methoxybenzyl)acrylamide |
Experimental Data
GR 46611
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33.000000000000000 | umol/L | -5.000000000000000 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
GR 46611
Statistics Data
GR 46611
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -5.000000000000000 | 1 | 1 |
Statistics Data Visualization
GR 46611
