Compound Summary
GR 127935 hydrochloride
Compound Information
GR 127935 hydrochloride
Compound Name: | GR 127935 hydrochloride |
Compound CID: | 11497466 |
Synonyms: | GR 127935 hydrochloride 148642-42-6 GR 127935 HCl GR 127935 hydrochloride hydrate GR127935 hydrochloride More... |
Iupac Name: | N-[4-methoxy-3-(4-methylpiperazin-1-yl)phenyl]-4-[2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)phenyl]benzamide;hydrochloride |
InChI: | InChI=1S/C29H31N5O3.ClH/c1-19-17-23(28-30-20(2)37-32-28)9-11-25(19)21-5-7-22(8-6-21)29(35)31-24-10-12-27(36-4)26(18-24)34-15-13-33(3)14-16-34;/h5-12,17-18H,13-16H2,1-4H3,(H,31,35);1H |
InChIKey: | SRVVUYIJVBLEJI-UHFFFAOYSA-N |
Canonical Smiles: | CC1=C(C=CC(=C1)C2=NOC(=N2)C)C3=CC=C(C=C3)C(=O)NC4=CC(=C(C=C4)OC)N5CCN(CC5)C.Cl |
Isomeric Smiles: | CC1=C(C=CC(=C1)C2=NOC(=N2)C)C3=CC=C(C=C3)C(=O)NC4=CC(=C(C=C4)OC)N5CCN(CC5)C.Cl |
Molecular Weight: | 534 |
Molecular Formula: | C29H32ClN5O3 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
GR 127935 hydrochloride
Molecular Weight: | 534 |
Molecular Formula: | C29H32ClN5O3 |
Hydrogen Bond Donor Count: | 2 |
Hydrogen Bond Acceptor Count: | 7 |
Rotatable Bond Count: | 6 |
Heavy Atom Count: | 38 |
Complexity: | 739 |
Synonyms
GR 127935 hydrochloride
| GR 127935 hydrochloride | GR 127935 hydrochloride |
|---|---|
GR 127935 hydrochloride |
148642-42-6 |
GR 127935 HCl |
GR 127935 hydrochloride hydrate |
GR127935 hydrochloride |
GR127935 (hydrochloride) |
N-4-Methoxy-3-(4-methyl-1-piperazinyl)phenyl-2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)-1,1-biphenyl-4-carboxamide hydrochloride |
CHEBI:64111 |
N-4-Methoxy-3-(4-methyl-1-piperazinyl)phenyl-2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)-1,1-biphenyl-4-carboxamide hydrate hydrochloride |
N-4-methoxy-3-(4-methylpiperazin-1-yl)phenyl-2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)biphenyl-4-carboxamide hydrochloride |
GR 127935 hydrochloride;GR-127935 hydrochloride |
MLS002153332 |
4-2-methoxy-5-({2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)biphenyl-4-ylcarbonyl}amino)phenyl-1-methylpiperazin-1-ium chloride |
SR-01000076115 |
SMR001230745 |
N-(4-methoxy-3-(4-methylpiperazin-1-yl)phenyl)-2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)biphenyl-4-carboxamide hydrochloride |
N-4-methoxy-3-(4-methylpiperazin-1-yl)phenyl-4-2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)phenylbenzamide;hydrochloride |
EU-0100790 |
GR-127935 hydrochloride |
SCHEMBL6017123 |
CHEMBL1256656 |
DTXSID0042587 |
BCP19014 |
Tox21_500790 |
AKOS024456623 |
CCG-222094 |
LP00790 |
NCGC00094125-01 |
NCGC00261475-01 |
BG177433 |
DS-017633 |
B6754 |
G 5793 |
J-008498 |
SR-01000076115-1 |
SR-01000076115-3 |
Q27133036 |
GR-127935 hydrochloride;GR127935 hydrochloride;GR 127935; GR-127935; GR 127935 HCl; GR 127935 |
N-4-methoxy-3-(4-methyl-1-piperazinyl)phenyl-2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)-1,1-biphenyl-4-carboxamide hydrate hydrochloride |
Experimental Data
GR 127935 hydrochloride
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33.000000000000000 | umol/L | -4.000000000000000 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
GR 127935 hydrochloride
Statistics Data
GR 127935 hydrochloride
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -4.000000000000000 | 1 | 1 |
Statistics Data Visualization
GR 127935 hydrochloride
