Compound Summary
Fluphenazine dihydrochloride
Compound Information
Fluphenazine dihydrochloride
Compound Name: | Fluphenazine dihydrochloride |
Compound CID: | 67356 |
Synonyms: | Fluphenazine dihydrochloride Fluphenazine hydrochloride 146-56-5 Prolixin Anatensol More... |
Iupac Name: | 2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-yl]ethanol;dihydrochloride |
InChI: | InChI=1S/C22H26F3N3OS.2ClH/c23-22(24,25)17-6-7-21-19(16-17)28(18-4-1-2-5-20(18)30-21)9-3-8-26-10-12-27(13-11-26)14-15-29;;/h1-2,4-7,16,29H,3,8-15H2;2*1H |
InChIKey: | MBHNWCYEGXQEIT-UHFFFAOYSA-N |
Canonical Smiles: | C1CN(CCN1CCCN2C3=CC=CC=C3SC4=C2C=C(C=C4)C(F)(F)F)CCO.Cl.Cl |
Isomeric Smiles: | C1CN(CCN1CCCN2C3=CC=CC=C3SC4=C2C=C(C=C4)C(F)(F)F)CCO.Cl.Cl |
Molecular Weight: | 510.4 |
Molecular Formula: | C22H28Cl2F3N3OS |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
Fluphenazine dihydrochloride
Molecular Weight: | 510.4 |
Molecular Formula: | C22H28Cl2F3N3OS |
Hydrogen Bond Donor Count: | 3 |
Hydrogen Bond Acceptor Count: | 8 |
Rotatable Bond Count: | 6 |
Heavy Atom Count: | 32 |
Complexity: | 544 |
Synonyms
Fluphenazine dihydrochloride
| Fluphenazine dihydrochloride | Fluphenazine dihydrochloride |
|---|---|
Fluphenazine dihydrochloride |
Fluphenazine hydrochloride |
146-56-5 |
Prolixin |
Anatensol |
Moditen |
Permitil |
Fluphenazine (dihydrochloride) |
Tensofin |
OMCA |
Squibb 4918 |
Calmansial |
Flufenazin |
Lyorodin |
Liogen |
Dapotum |
Fluphenazine chloride |
UNII-ZOU145W1XL |
Fluphenazine DiHCl |
Fluorophenazine dihydrochloride |
ZOU145W1XL |
Valamina |
1-(2-Hydroxyethyl)-4-(3-(2-trifluoromethyl-10-phenothiazinylpropyl)piperazine dihydrochloride |
Trancin |
A 4077 |
1-Piperazineethanol, 4-(3-(2-(trifluoromethyl)-10H-phenothiazin-10-yl)propyl)-, dihydrochloride |
1-piperazineethanol, 4-3-2-(trifluoromethyl)-10H-phenothiazin-10-ylpropyl-, dihydrochloride |
Permitil hydrochloride |
FLUPHENAZINE HCL |
10-(3-(4-(2-Hydroxyethyl)piperazinyl)propyl)-2-trifluoromethylphenothiazine dihydrochloride |
2-4-3-2-(trifluoromethyl)phenothiazin-10-ylpropylpiperazin-1-ylethanol;dihydrochloride |
2-(4-(3-(2-(Trifluoromethyl)-10H-phenothiazin-10-yl)propyl)piperazin-1-yl)ethanol dihydrochloride |
CCRIS 4032 |
NSC-179197 |
SR-01000003048 |
EINECS 205-674-1 |
NSC 179197 |
Siqualone |
Fluphenazine 2HCl |
Prolixin (TN) |
2-(4-(3-(2-(trifluoromethyl)-10H-phenothiazin-10-yl)propyl)piperazin-1-yl)ethan-1-ol dihydrochloride |
2-(4-{3-2-(trifluoromethyl)-10H-phenothiazin-10-ylpropyl}piperazin-1-yl)ethan-1-ol dihydrochloride |
Prestwick_225 |
Fluphenazine hydrochloride USP:BAN:JAN |
C22H27ClF3N3OS |
4-(3-(2-(Trifluoromethyl)phenothiazin-10-yl)propyl)-1-piperazineethanol dihydrochloride |
SCHEMBL41634 |
SPECTRUM1500994 |
CHEBI:5126 |
FLUFENAZINE HYDROCHLORIDE |
CHEMBL1448187 |
DTXSID00892922 |
HMS1568P22 |
HMS1921O14 |
BCP18079 |
HY-A0081 |
Tox21_500555 |
MFCD00055212 |
s4569 |
Fluphenazine hydrochloride (JAN/USP) |
AKOS015960787 |
CCG-212902 |
CS-4290 |
LP00555 |
1-Piperazineethanol, 4-(3-(2-(trifluoromethyl)phenothiazin-10-yl)propyl)-, dihydrochloride |
4-3-2-(Trifluoromethyl)-10H-phenothiazin-10-ylpropyl-1-piperazineethanol dihydrochloride |
NCGC00093941-01 |
NCGC00093941-02 |
NCGC00093941-03 |
NCGC00261240-01 |
AC-12201 |
BS-15804 |
S4569 Fluphenazine (dihydrochloride).cd |
AB0019790 |
EU-0100555 |
FT-0668755 |
V0295 |
C72785 |
D00791 |
F 4765 |
SR-01000003048-2 |
SR-01000003048-9 |
W-108125 |
Q27295826 |
Z2784093501 |
Fluphenazine Dihydrochloride 1.0 mg/ml in Methanol (as free base) |
Fluphenazine dihydrochloride, European Pharmacopoeia (EP) Reference Standard |
Fluphenazine Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material |
Fluphenazine hydrochloride, United States Pharmacopeia (USP) Reference Standard |
2-(4-{3-2-(Trifluoromethyl)-10H-phenothiazin-10-ylpropyl}-1-piperazinyl)ethanol dihydrochloride |
2-4-3-2-(trifluoromethyl)phenothiazin-10-ylpropylpiperazin-1-ylethanol,dihydrochloride |
Fluphenazine dihydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material |
Experimental Data
Fluphenazine dihydrochloride
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33.000000000000000 | umol/L | 16.000000000000000 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
Fluphenazine dihydrochloride
Statistics Data
Fluphenazine dihydrochloride
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 16.000000000000000 | 1 | 1 |
Statistics Data Visualization
Fluphenazine dihydrochloride
