Compound Summary
EIPA
Compound Information
EIPA
Compound Name: | EIPA |
Compound CID: | 1795 |
Synonyms: | EIPA 1154-25-2 5-(N-Ethyl-N-isopropyl)amiloride Ethylisopropylamiloride 5-(Ethylisopropyl)amiloride More... |
Iupac Name: | 3-amino-6-chloro-N-(diaminomethylidene)-5-[ethyl(propan-2-yl)amino]pyrazine-2-carboxamide |
InChI: | InChI=1S/C11H18ClN7O/c1-4-19(5(2)3)9-7(12)16-6(8(13)17-9)10(20)18-11(14)15/h5H,4H2,1-3H3,(H2,13,17)(H4,14,15,18,20) |
InChIKey: | QDERNBXNXJCIQK-UHFFFAOYSA-N |
Canonical Smiles: | CCN(C1=NC(=C(N=C1Cl)C(=O)N=C(N)N)N)C(C)C |
Isomeric Smiles: | CCN(C1=NC(=C(N=C1Cl)C(=O)N=C(N)N)N)C(C)C |
Molecular Weight: | 299.76 |
Molecular Formula: | C11H18ClN7O |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
EIPA
Molecular Weight: | 299.76 |
Molecular Formula: | C11H18ClN7O |
Hydrogen Bond Donor Count: | 3 |
Hydrogen Bond Acceptor Count: | 5 |
Rotatable Bond Count: | 4 |
Heavy Atom Count: | 20 |
Complexity: | 372 |
Synonyms
EIPA
| EIPA | EIPA |
|---|---|
EIPA |
1154-25-2 |
5-(N-Ethyl-N-isopropyl)amiloride |
Ethylisopropylamiloride |
5-(Ethylisopropyl)amiloride |
Ethyl isopropyl amiloride |
UNII-VW50CE070T |
3-Amino-N-(aminoiminomethyl)-6-chloro-5-ethyl(1-methylethyl)amino-2-pyrazinecarboxamide |
5-(N-ethyl-N-isopropyl)-Amiloride |
N-Amidino-3-amino-5-ethylisopropylamino-6-chloropyrazine carboxamide |
3-Amino-N-carbamimidoyl-6-chloro-5-(ethyl(isopropyl)amino)pyrazine-2-carboxamide |
3-amino-6-chloro-N-(diaminomethylidene)-5-ethyl(propan-2-yl)aminopyrazine-2-carboxamide |
CHEMBL517986 |
VW50CE070T |
MFCD00151710 |
3-Amino-N-(aminoiminomethyl)-6-chloro-5-(ethyl(1-methylethyl)amino)pyrazinecarboxamide |
L593754;MH 12-43 |
3-amino-N-carbamimidoyl-6-chloro-5-ethyl(isopropyl)aminopyrazine-2-carboxamide |
2-Pyrazinecarboxamide, 3-amino-N-(aminoiminomethyl)-6-chloro-5-ethyl(1-methylethyl)amino- |
Ethylisopropyl amiloride |
MH 12-43 |
Lopac-A-3085 |
cid_1795 |
Pyrazinecarboxamide, 3-amino-N-(aminoiminomethyl)-6-chloro-5-(ethyl(1-methylethyl)amino)- |
Lopac0_000045 |
REGID_for_CID_1795 |
MLS000860017 |
GTPL4186 |
SCHEMBL9852524 |
DTXSID80151084 |
CHEBI:136538 |
HMS2235B09 |
HMS3260I11 |
HMS3740E09 |
ZINC3871092 |
Tox21_500045 |
5-(N-ethyl-N-isopropyl)amiloride |
BDBM50270005 |
AKOS024281351 |
AKOS030241586 |
CCG-204141 |
CS-7935 |
LP00045 |
MCULE-2107271291 |
SDCCGSBI-0050034.P002 |
NCGC00015047-01 |
NCGC00015047-02 |
NCGC00015047-03 |
NCGC00015047-04 |
NCGC00015047-05 |
NCGC00015047-06 |
NCGC00093559-01 |
NCGC00093559-02 |
NCGC00260730-01 |
AS-30503 |
SMR000326875 |
ST044507 |
DB-041266 |
HY-101840 |
B7389 |
EU-0100045 |
FT-0602002 |
MH 12-43L593754 |
L593754;MH 12-43;Ethylisopropylamiloride |
A 3085 |
L593754 |
SR-01000075673 |
J-003288 |
SR-01000075673-1 |
Q27077241 |
{3-amino-6-chloro-5-ethyl(methylethyl)aminopyrazin-2-yl}-N-(???methyl)carbox amide |
Experimental Data
EIPA
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33.000000000000000 | umol/L | -7.000000000000000 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
EIPA
Statistics Data
EIPA
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -7.000000000000000 | 1 | 1 |
Statistics Data Visualization
EIPA
