Compound Summary
EFLORNITHINE HYDROCHLORIDE
Compound Information
EFLORNITHINE HYDROCHLORIDE
Compound Name: | EFLORNITHINE HYDROCHLORIDE |
Compound CID: | 57004 |
Synonyms: | EFLORNITHINE HYDROCHLORIDE 68278-23-9 Eflornithine HCl dfmo DL-alpha-Difluoromethylornithine hydrochloride More... |
Iupac Name: | 2,5-diamino-2-(difluoromethyl)pentanoic acid;hydrochloride |
InChI: | InChI=1S/C6H12F2N2O2.ClH/c7-4(8)6(10,5(11)12)2-1-3-9;/h4H,1-3,9-10H2,(H,11,12);1H |
InChIKey: | VKDGNNYJFSHYKD-UHFFFAOYSA-N |
Canonical Smiles: | C(CC(C(F)F)(C(=O)O)N)CN.Cl |
Isomeric Smiles: | C(CC(C(F)F)(C(=O)O)N)CN.Cl |
Molecular Weight: | 218.63 |
Molecular Formula: | C6H13ClF2N2O2 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
EFLORNITHINE HYDROCHLORIDE
Molecular Weight: | 218.63 |
Molecular Formula: | C6H13ClF2N2O2 |
Hydrogen Bond Donor Count: | 4 |
Hydrogen Bond Acceptor Count: | 6 |
Rotatable Bond Count: | 5 |
Heavy Atom Count: | 13 |
Complexity: | 166 |
Synonyms
EFLORNITHINE HYDROCHLORIDE
| EFLORNITHINE HYDROCHLORIDE | EFLORNITHINE HYDROCHLORIDE |
|---|---|
EFLORNITHINE HYDROCHLORIDE |
68278-23-9 |
Eflornithine HCl |
dfmo |
DL-alpha-Difluoromethylornithine hydrochloride |
DFMO HCl |
Eflornithine (hydrochloride) |
2,5-diamino-2-(difluoromethyl)pentanoic acid hydrochloride |
Vaniqa |
Eflornithine hydrochloride anhydrous |
DFMO HCl;Eflornithine HCl |
MLS000069341 |
(RS)-eflornithine hydrochloride |
2,5-diamino-2-(difluoromethyl)pentanoic acid;hydrochloride |
D,L-alpha-Difluoromethylornithine hydrochloride |
H-alpha-Difluoro-Me-DL-Orn-OH HCl HO |
NCGC00093850-01 |
SMR000058442 |
.alpha.-DFMO HCl |
DSSTox_CID_25765 |
DSSTox_RID_81107 |
Eflornithine . HCl . HO;DFMO . HCl . HO;alpha-Difluoromethylornithine . HCl . HO |
DSSTox_GSID_45765 |
DFMO;MDL71782;RMI71782;alpha-difluoromethylornithine |
DL-Ornithine, monohydrochloride |
CAS-96020-91-6 |
2-(Difluoromethyl)-DL-ornithine monohydrochloride |
CCRIS 5805 |
Eflornithinehydrochloride |
NSC-270295 |
EINECS 269-532-0 |
SR-01000076229 |
2-(Difluoromethyl)-DL-ornithine hydrochloride |
DFMO hydrochloride |
2-(Difluoromethyl)-DL-ornithine HCl |
DL-Ornithine, 2-(difluoromethyl)-, monohydrochloride |
NSC 270295 |
NSC 337250 |
Opera_ID_46 |
Eflornithine Hydrocloride |
C6H13ClF2N2O2 |
Ornithine, 2-(difluoromethyl)-, monohydrochloride |
MLS001332583 |
CHEMBL536971 |
SCHEMBL3022583 |
HY-B0744A |
AOB5501 |
DTXSID601019072 |
L-EFLORNITHINE HYDROCHLORIDE |
BCP11748 |
DL-alpha-Difluoromethylornithine HCl |
Tox21_111224 |
Tox21_500429 |
AC-388 |
MFCD00274036 |
NSC270295 |
AKOS015895186 |
Tox21_111224_1 |
CCG-221733 |
KS-1261 |
LP00429 |
NCGC00015316-05 |
NCGC00261114-01 |
DL-|A-Difluoromethylornithine hydrochloride |
AB0012930 |
E0947 |
EU-0100429 |
FT-0630774 |
DL-2-(Difluoromethyl)-ornithine hydrochloride |
H-alpha-Difluoro-Me-DL-Orn-OH . HCl . HO |
278E239 |
A836071 |
A836749 |
DL--Difluoromethylornithine Hydrochloride Monohydrate |
SR-01000076229-1 |
DL-alpha-Difluoromethylornithine hydrochloride hydrate |
Q27291165 |
2,5-diamino-2-(difluoromethyl)pentanoic acid,hydrochloride |
2,5-bis(azanyl)-2-bis(fluoranyl)methylpentanoic acid hydrochloride |
2,5-diamino-2-(difluoromethyl)pentanoic acid hydrochloride;Eflornithine HCl |
Experimental Data
EFLORNITHINE HYDROCHLORIDE
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33.000000000000000 | umol/L | -4.000000000000000 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
EFLORNITHINE HYDROCHLORIDE
Statistics Data
EFLORNITHINE HYDROCHLORIDE
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -4.000000000000000 | 1 | 1 |
Statistics Data Visualization
EFLORNITHINE HYDROCHLORIDE
