Compound Summary
Dithiothreitol
Compound Information
Dithiothreitol
Compound Name: | Dithiothreitol |
Compound CID: | 446094 |
Synonyms: | Dithiothreitol DL-1,4-Dithiothreitol dl-Dithiothreitol 3483-12-3 27565-41-9 More... |
Iupac Name: | (2S,3S)-1,4-bis(sulfanyl)butane-2,3-diol |
InChI: | InChI=1S/C4H10O2S2/c5-3(1-7)4(6)2-8/h3-8H,1-2H2/t3-,4-/m1/s1 |
InChIKey: | VHJLVAABSRFDPM-QWWZWVQMSA-N |
Canonical Smiles: | C(C(C(CS)O)O)S |
Isomeric Smiles: | C([C@H]([C@@H](CS)O)O)S |
Molecular Weight: | 154.3 |
Molecular Formula: | C4H10O2S2 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
Dithiothreitol
Molecular Weight: | 154.3 |
Molecular Formula: | C4H10O2S2 |
Hydrogen Bond Donor Count: | 4 |
Hydrogen Bond Acceptor Count: | 4 |
Rotatable Bond Count: | 3 |
Heavy Atom Count: | 8 |
Complexity: | 52 |
Synonyms
Dithiothreitol
| Dithiothreitol | Dithiothreitol |
|---|---|
Dithiothreitol |
DL-1,4-Dithiothreitol |
dl-Dithiothreitol |
3483-12-3 |
27565-41-9 |
(2S,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL |
1,4-Dithiothreitol |
D-Dithiothreitol |
D-1,4-Dithiothreitol |
D-Dtt |
(2S,3S)-1,4-bis(sulfanyl)butane-2,3-diol |
1,4-Dithiothreithol |
Clelands reagent |
(2S,3S)-1,4-disulfanylbutane-2,3-diol |
DTT |
MFCD00004877 |
D-threo-1,4-Dimercapto-2,3-butanediol |
threo-1,4-Dimercapto-2,3-butanediol |
CHEBI:42170 |
cis-2,3-Dihydroxy-1,4-butanedithiol |
Sputolysin |
35454-97-8 |
rac-Dithiothreitol |
DTV |
dithio threitol |
WR 34678 |
(R*,R*)-1,4-Dimercaptobutane-2,3-diol |
Reagents, Clelands |
2,3-Butanediol, 1,4-dimercapto-, (R*,R*)- |
(+/-)-Dithiothreitol |
DL-Dithiothreitol, 99% |
DL-Dithiothreitol, powder |
DTT (threitol derivative) |
DTT, 1,4-Dithiothreitol |
D,L-Dithiothreitol (DTT) |
SCHEMBL10601 |
CHEMBL1232392 |
DL-Dithiothreitol, >=99.0% |
DTXSID5041017 |
Dithiothreitol, biochemical grade |
ZINC3852211 |
EINECS 240-263-0 |
ETHYL4-NITRO-L-PHENYLALANINE |
EBD485460 |
AKOS005259570 |
AKOS015855399 |
AT-2091 |
CCG-207964 |
DB02184 |
DL-Dithiothreitol, >=99.0% (RT) |
Threitol, 1,4-dithio- (7CI,8CI) |
BRN 2036371 |
Threitol, 1,4-dithio-, L- (8CI) |
threo-2,3-Dihydroxy-1,4-butanedithiol |
DL-1,4-Dimercapto-2,3-dihydroxybutane |
DTT, Dithiothreitol (Clelands Reagenz) |
(+/-)-1,4-Dimercapto-2,3-butanediol |
AS-57473 |
DL-Dithiothreitol solution, 1 M in H2O |
B7294 |
X4647 |
1698-EP2270001A1 |
1698-EP2270004A1 |
1698-EP2270008A1 |
1698-EP2270014A1 |
1698-EP2272516A2 |
1698-EP2272827A1 |
1698-EP2272972A1 |
1698-EP2272973A1 |
1698-EP2275102A1 |
1698-EP2275412A1 |
1698-EP2275413A1 |
1698-EP2275414A1 |
1698-EP2277867A2 |
1698-EP2277872A1 |
1698-EP2277876A1 |
1698-EP2277881A1 |
1698-EP2280003A2 |
1698-EP2280011A1 |
1698-EP2280012A2 |
1698-EP2281563A1 |
1698-EP2284178A2 |
1698-EP2284179A2 |
1698-EP2287155A1 |
1698-EP2287156A1 |
1698-EP2289893A1 |
1698-EP2289894A2 |
1698-EP2292593A2 |
1698-EP2292614A1 |
1698-EP2292617A1 |
1698-EP2295406A1 |
1698-EP2295410A1 |
1698-EP2295412A1 |
1698-EP2295413A1 |
1698-EP2295432A1 |
1698-EP2295550A2 |
1698-EP2298305A1 |
1698-EP2298743A1 |
1698-EP2298744A2 |
1698-EP2298772A1 |
1698-EP2298779A1 |
1698-EP2298783A1 |
1698-EP2301928A1 |
1698-EP2301939A1 |
1698-EP2305250A1 |
1698-EP2305682A1 |
1698-EP2305687A1 |
1698-EP2305808A1 |
1698-EP2305825A1 |
1698-EP2308839A1 |
1698-EP2308855A1 |
1698-EP2308877A1 |
1698-EP2308879A1 |
1698-EP2308880A1 |
1698-EP2308883A1 |
1698-EP2311807A1 |
1698-EP2311814A1 |
1698-EP2311818A1 |
1698-EP2311825A1 |
1698-EP2311829A1 |
1698-EP2311837A1 |
1698-EP2311842A2 |
1698-EP2314576A1 |
1698-EP2316459A1 |
1698-EP2316835A1 |
D97824 |
DL-Dithiothreitol, BioUltra, >=99.0% (RT) |
DL-Dithiothreitol, for electrophoresis, >=99% |
M02712 |
M02716 |
(R-(R*,R*))-1,4-Dimercaptobutane-2,3-diol |
DL-Dithiothreitol, SAJ special grade, >=98.0% |
DL-Dithiothreitol, Vetec(TM) reagent grade, 98% |
Q414783 |
(+/-) Dithiothreitol molecular biology grade >99% |
2,3-BUTANEDIOL, 1,4-DIMERCAPTO-, L-threo- |
DL-Dithiothreitol, BioXtra, >=99.0% (titration) |
2,3-Butanediol, 1,4-dimercapto-, (2R,3R)-rel- (9CI) |
DL-Dithiothreitol, >=98% (HPLC), >=99.0% (titration) |
UNII-T8ID5YZU6Y component VHJLVAABSRFDPM-QWWZWVQMSA-N |
2,3-Butanediol, 1,4-dimercapto-, (R-(R*,R*))- (9CI) |
DL-Dithiothreitol; Cleland inverted exclamation mark s reagent |
DL-Dithiothreitol, BioUltra, for molecular biology, >=99.5% (RT) |
DL-Dithiothreitol solution, BioUltra, for molecular biology, ~1 M in H2O |
DL-Dithiothreitol, for molecular biology, >=98% (HPLC), >=99% (titration) |
Experimental Data
Dithiothreitol
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Drosophila melanogaster | 20.000000000000000 | umol/L | 44.630000000000000 | 48.320000000000000 | 8.256000000000000 | NS | FEMALES | 33008901 | Inactive | ||||
| Drosophila melanogaster | 200.000000000000000 | umol/L | 43.170000000000000 | 45.600000000000000 | 5.636000000000000 | NS | MALES | 33008901 | Inactive | ||||
| Caenorhabditis elegans | 10.000000000000000 | umol/L | 17.010000000000000 | 17.420000000000000 | 2.387000000000000 | NS | N2 | 33008901 | Inactive | ||||
| Caenorhabditis elegans | 100.000000000000000 | umol/L | 15.780000000000000 | 16.180000000000000 | 2.564000000000000 | NS | N2 | 33008901 | Inactive |
Experimental Data Visualization
Dithiothreitol
Statistics Data
Dithiothreitol
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 2.564000000000000 | 1 | 2 | |
| Drosophila melanogaster | 8.256000000000000 | 1 | 2 |
Statistics Data Visualization
Dithiothreitol
