Compound Summary
Dichloroacetate
Compound Information
Dichloroacetate
Compound Name: | Dichloroacetate |
Compound CID: | 25975 |
Synonyms: | Dichloroacetate 2,2-dichloroacetate Dichloracetate Dichloroacetate ion 13425-80-4 More... |
Iupac Name: | 2,2-dichloroacetate |
InChI: | InChI=1S/C2H2Cl2O2/c3-1(4)2(5)6/h1H,(H,5,6)/p-1 |
InChIKey: | JXTHNDFMNIQAHM-UHFFFAOYSA-M |
Canonical Smiles: | C(C(=O)[O-])(Cl)Cl |
Isomeric Smiles: | C(C(=O)[O-])(Cl)Cl |
Molecular Weight: | 127.93 |
Molecular Formula: | C2HCl2O2- |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
Dichloroacetate
Molecular Weight: | 127.93 |
Molecular Formula: | C2HCl2O2- |
Hydrogen Bond Donor Count: | 0 |
Hydrogen Bond Acceptor Count: | 2 |
Rotatable Bond Count: | 0 |
Heavy Atom Count: | 6 |
Complexity: | 55.1 |
Synonyms
Dichloroacetate
| Dichloroacetate | Dichloroacetate |
|---|---|
Dichloroacetate |
2,2-dichloroacetate |
Dichloracetate |
Dichloroacetate ion |
13425-80-4 |
Dichloroacetic acid ion(1-) |
DCA |
BRN 3903873 |
2q8h |
ACETIC ACID, DICHLORO-, ION(1-) |
2,2-bis(chloranyl)ethanoate |
GTPL4518 |
CHEBI:28240 |
DTXSID40158610 |
STL483470 |
NCGC00241105-01 |
68626-EP2292227A2 |
68626-EP2292628A2 |
68626-EP2298776A1 |
68626-EP2308861A1 |
68626-EP2374454A1 |
A839686 |
Q27077050 |
Experimental Data
Dichloroacetate
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 50.000000000000000 | ug/mL | 20.180000000000000 | 21.680000000000000 | 0.070000000000000 | 27.900000000000000 | 28.550000000000000 | 0.020000000000000 | S | N2 | 21153705 | Active | |
| Caenorhabditis elegans | 50.000000000000000 | ug/mL | 22.010000000000000 | 23.710000000000000 | 0.080000000000000 | 29.890000000000000 | 31.220000000000000 | 0.040000000000000 | S | N2 | 21153705 | Active | |
| Caenorhabditis elegans | 50.000000000000000 | ug/mL | 23.860000000000000 | 25.740000000000000 | 0.080000000000000 | 32.100000000000000 | 36.400000000000000 | 0.130000000000000 | S | N2 | 21153705 | Active | |
| Caenorhabditis elegans | 50.000000000000000 | ug/mL | 21.670000000000000 | 22.510000000000000 | 0.040000000000000 | 28.350000000000000 | 30.330000000000000 | 0.070000000000000 | S | N2 | 21153705 | Active | |
| Caenorhabditis elegans | 50.000000000000000 | ug/mL | 17.010000000000000 | 20.280000000000000 | 0.190000000000000 | 26.140000000000000 | 30.330000000000000 | 0.160000000000000 | S | N2 | 21153705 | Active | |
| Caenorhabditis elegans | 50.000000000000000 | ug/mL | 6.730000000000000 | 6.790000000000000 | S | N2 | 33683565 | Active | |||||
| Caenorhabditis elegans | 50.000000000000000 | ug/mL | 19.220000000000000 | 16.030000000000000 | S | N2 | 33683565 | Active |
Experimental Data Visualization
Dichloroacetate
Statistics Data
Dichloroacetate
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 19.220000000000000 | 16.030000000000000 | 2 | 7 |
Statistics Data Visualization
Dichloroacetate
