Compound Summary
DEXTROTHYROXINE SODIUM
Compound Information
DEXTROTHYROXINE SODIUM
Compound Name: | DEXTROTHYROXINE SODIUM |
Compound CID: | 23690433 |
Synonyms: | DEXTROTHYROXINE SODIUM D-Thyroxine sodium salt Debetrol Dethyrona Detyroxin More... |
Iupac Name: | sodium;(2R)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoate |
InChI: | InChI=1S/C15H11I4NO4.Na/c16-8-4-7(5-9(17)13(8)21)24-14-10(18)1-6(2-11(14)19)3-12(20)15(22)23;/h1-2,4-5,12,21H,3,20H2,(H,22,23);/q;+1/p-1/t12-;/m1./s1 |
InChIKey: | YDTFRJLNMPSCFM-UTONKHPSSA-M |
Canonical Smiles: | C1=C(C=C(C(=C1I)OC2=CC(=C(C(=C2)I)O)I)I)CC(C(=O)[O-])N.[Na+] |
Isomeric Smiles: | C1=C(C=C(C(=C1I)OC2=CC(=C(C(=C2)I)O)I)I)C[C@H](C(=O)[O-])N.[Na+] |
Molecular Weight: | 798.85 |
Molecular Formula: | C15H10I4NNaO4 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
DEXTROTHYROXINE SODIUM
Molecular Weight: | 798.85 |
Molecular Formula: | C15H10I4NNaO4 |
Hydrogen Bond Donor Count: | 2 |
Hydrogen Bond Acceptor Count: | 5 |
Rotatable Bond Count: | 5 |
Heavy Atom Count: | 25 |
Complexity: | 426 |
Synonyms
DEXTROTHYROXINE SODIUM
| DEXTROTHYROXINE SODIUM | DEXTROTHYROXINE SODIUM |
|---|---|
DEXTROTHYROXINE SODIUM |
D-Thyroxine sodium salt |
Debetrol |
Dethyrona |
Detyroxin |
Dextroid |
Dextroxin |
137-53-1 |
UNII-J60FX7V025 |
J60FX7V025 |
Sodium (R)-2-amino-3-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)propanoate |
dynothel |
Lisolipin |
Travenon |
Nadrothyron D |
Sodium D-thyroxine |
Sodium-D-thyroxine |
D-T4 sodium |
Sodium D-T4 |
Sodium dextrothyroxine |
Dextrothyroxine sodium anhydrous |
Dextrotiroxina sodica |
Destrotirossina sodica DCIT |
Thyroxine monosodium salt, D- |
Destrotirossina sodica |
Thyroxine, monosodium salt, d- |
Dextrothyroxine sodique |
Dextrothyroxinum natricum |
Dextrotiroxina sodica INN-Spanish |
EINECS 205-301-2 |
Dextrothyroxine sodique INN-French |
Dextrothyroxinum natricum INN-Latin |
Sodium D-3,3,5,5-tetraiodothyronine |
Dextrothyroxine sodium INN |
3:5:3:5-Tetraiodo-D-thyronine sodium" |
3,3,5,5-Tetraiodo-d-thyronine, sodium salt |
THYROID |
Sodium d-3-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)alanine |
SCHEMBL582058 |
CHEMBL1200777 |
D-3,5-Diiodo-4-(3,5-Diiodo-4-hydroxyphenoxy)-phenylalanine sodium salt |
MFCD00063057 |
Q-201830 |
Q27281241 |
D-Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-, monosodium salt (9CI) |
sodium;(2R)-2-amino-3-4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenylpropanoate |
Experimental Data
DEXTROTHYROXINE SODIUM
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Rattus norvegicus | 0.500000000000000 | ug/g | 744.000000000000000 | 825.000000000000000 | 10.890000000000000 | Unclear | FEMALES | 6632988 | |||||
| Rattus norvegicus | 2.000000000000000 | ug/g | 744.000000000000000 | 927.000000000000000 | 24.600000000000000 | Unclear | FEMALES | 6632988 | |||||
| Rattus norvegicus | 2.000000000000000 | ug/g | 744.000000000000000 | 828.000000000000000 | 11.290000000000000 | Unclear | MALES | 6632988 | |||||
| Rattus norvegicus | 0.500000000000000 | ug/g | 744.000000000000000 | 795.000000000000000 | 6.850000000000000 | Unclear | MALES | 6632988 | |||||
| Rattus norvegicus | 1.000000000000000 | ug/g | 744.000000000000000 | 864.000000000000000 | 16.130000000000000 | Unclear | MALES | 6632988 | |||||
| Rattus norvegicus | 2.000000000000000 | ug/g | 744.000000000000000 | 954.000000000000000 | 28.230000000000000 | Unclear | FEMALES | 6632988 |
Experimental Data Visualization
DEXTROTHYROXINE SODIUM
Statistics Data
DEXTROTHYROXINE SODIUM
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Rattus norvegicus | 28.230000000000000 | 1 | 6 |
Statistics Data Visualization
DEXTROTHYROXINE SODIUM
