Compound Summary
Cryptotanshinone
Compound Information
Cryptotanshinone
Compound Name: | Cryptotanshinone |
Compound CID: | 160254 |
Synonyms: | Cryptotanshinone 35825-57-1 Tanshinone c (R)-1,2,6,7,8,9-Hexahydro-1,6,6-trimethyl-phenanthro(1,2-b)furan-10,11-dione Cryptotanshinon More... |
Iupac Name: | (1R)-1,6,6-trimethyl-2,7,8,9-tetrahydro-1H-naphtho[1,2-g][1]benzofuran-10,11-dione |
InChI: | InChI=1S/C19H20O3/c1-10-9-22-18-12-6-7-13-11(5-4-8-19(13,2)3)15(12)17(21)16(20)14(10)18/h6-7,10H,4-5,8-9H2,1-3H3/t10-/m0/s1 |
InChIKey: | GVKKJJOMQCNPGB-JTQLQIEISA-N |
Canonical Smiles: | CC1COC2=C1C(=O)C(=O)C3=C2C=CC4=C3CCCC4(C)C |
Isomeric Smiles: | C[C@H]1COC2=C1C(=O)C(=O)C3=C2C=CC4=C3CCCC4(C)C |
Molecular Weight: | 296.4 |
Molecular Formula: | C19H20O3 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
Cryptotanshinone
Molecular Weight: | 296.4 |
Molecular Formula: | C19H20O3 |
Hydrogen Bond Donor Count: | 0 |
Hydrogen Bond Acceptor Count: | 3 |
Rotatable Bond Count: | 0 |
Heavy Atom Count: | 22 |
Complexity: | 571 |
Synonyms
Cryptotanshinone
| Cryptotanshinone | Cryptotanshinone |
|---|---|
Cryptotanshinone |
35825-57-1 |
Tanshinone c |
(R)-1,2,6,7,8,9-Hexahydro-1,6,6-trimethyl-phenanthro(1,2-b)furan-10,11-dione |
Cryptotanshinon |
UNII-5E9SXT166N |
C19H20O3 |
(1R)-1,6,6-trimethyl-2,7,8,9-tetrahydro-1H-naphtho1,2-g1benzofuran-10,11-dione |
MLS001049002 |
5E9SXT166N |
MFCD07636810 |
SMR000387041 |
(R)-1,6,6-trimethyl-1,2,6,7,8,9-hexahydrophenanthro1,2-bfuran-10,11-dione |
1,2,6,7,8,9-Hexahydro-1,6,6-trimethyl1,2-bfuran-10,11-dione |
(-)-Cryptotanshinone |
(1R)-1,6,6-trimethyl-2,3a,7,8,9,11a-hexahydro-1H-naphtho1,2-gbenzofuran-10,11-dione |
SR-01000758222 |
NSC686518 |
SPECTRUM1505812 |
CHEMBL187460 |
cid_160254 |
SCHEMBL5940386 |
BDBM57938 |
CHEBI:149838 |
Phenanthro(1,2-b)furan-10,11-dione, 1,2,6,7,8,9-hexahydro-1,6,6-trimethyl-, (R)- |
HMS2269A22 |
BCP02909 |
Cryptotanshinone, >=90% (HPLC) |
Cryptotanshinone, >=98% (HPLC) |
HY-N0174 |
ZINC2109876 |
Cryptotanshinone, analytical standard |
s2285 |
AKOS015895392 |
BCP9000554 |
CCG-208561 |
CS-3276 |
DB15579 |
MCULE-9919031730 |
NSC-686518 |
Phenanthro1,2-bfuran-10,11-dione,1,2,6,7,8,9-hexahydro-1,6,6-trimethyl-, (R)- |
NCGC00163650-01 |
NCGC00163650-02 |
4733-35-1 |
BS-17094 |
NCI60_031208 |
BCP0726000307 |
N1843 |
W2147 |
825C571 |
A822990 |
Q-100429 |
SR-01000758222-3 |
SR-01000758222-4 |
BRD-K33336844-001-05-3 |
Q27261913 |
Phenanthro1,11-dione, 1,2,6,7,8,9-hexahydro-1,6,6-trimethyl-, (1R)- |
(1R)-1,6,6-trimethyl-2,7,8,9-tetrahydro-1H-naphtho1,2-gbenzofuran-10,11-dione |
(1R)-1,6,6-trimethyl-2,7,8,9-tetrahydro-1H-naphtho1,2-gbenzofuran-10,11-quinone |
(R)-(-)-1,6,6-Trimethyl-1,2,6,7,8,9-hexahydrophenanthro1,2-bfuran-10,11-dione |
(R)-1,2,6,7,8,9-Hexahydro-1,6,6-trimethylphenanthro1,2-bfuran-10,11-dione |
1,2,6,7,8,9-hexahydro-1,6,6-trimethyl- (R)-phenanthro(1,2-b)furan-10,11-dione |
Experimental Data
Cryptotanshinone
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 100.000000000000000 | umol/L | 15.800000000000000 | 15.090000000000000 | -4.459000000000000 | NS | N2 | 33008901 | Inactive | ||||
| Drosophila melanogaster | 20.000000000000000 | umol/L | 44.630000000000000 | 47.780000000000000 | 7.063000000000000 | S | FEMALES | 33008901 | Active | ||||
| Drosophila melanogaster | 200.000000000000000 | umol/L | 43.170000000000000 | 48.960000000000000 | 13.410000000000000 | S | MALES | 33008901 | Active | ||||
| Caenorhabditis elegans | 10.000000000000000 | umol/L | 17.010000000000000 | 15.620000000000000 | -8.221000000000000 | NS | N2 | 33008901 | Inactive |
Experimental Data Visualization
Cryptotanshinone
Statistics Data
Cryptotanshinone
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -4.459000000000000 | 1 | 2 | |
| Drosophila melanogaster | 13.410000000000000 | 1 | 2 |
Statistics Data Visualization
Cryptotanshinone
