Compound Summary
Clorotepine
Compound Information
Clorotepine
Compound Name: | Clorotepine |
Compound CID: | 1238 |
Synonyms: | Clorotepine Octoclothepin Octoclothepine Clotepin Clothepin More... |
Iupac Name: | 1-(3-chloro-5,6-dihydrobenzo[b][1]benzothiepin-5-yl)-4-methylpiperazine |
InChI: | InChI=1S/C19H21ClN2S/c1-21-8-10-22(11-9-21)17-12-14-4-2-3-5-18(14)23-19-7-6-15(20)13-16(17)19/h2-7,13,17H,8-12H2,1H3 |
InChIKey: | XRYLGRGAWQSVQW-UHFFFAOYSA-N |
Canonical Smiles: | CN1CCN(CC1)C2CC3=CC=CC=C3SC4=C2C=C(C=C4)Cl |
Isomeric Smiles: | CN1CCN(CC1)C2CC3=CC=CC=C3SC4=C2C=C(C=C4)Cl |
Molecular Weight: | 344.9 |
Molecular Formula: | C19H21ClN2S |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
Clorotepine
Molecular Weight: | 344.9 |
Molecular Formula: | C19H21ClN2S |
Hydrogen Bond Donor Count: | 0 |
Hydrogen Bond Acceptor Count: | 3 |
Rotatable Bond Count: | 1 |
Heavy Atom Count: | 23 |
Complexity: | 399 |
Synonyms
Clorotepine
| Clorotepine | Clorotepine |
|---|---|
Clorotepine |
Octoclothepin |
Octoclothepine |
Clotepin |
Clothepin |
13448-22-1 |
CHEMBL64249 |
1-(3-chloro-5,6-dihydrobenzob1benzothiepin-5-yl)-4-methylpiperazine |
1-(8-Chloro-10,11-dihydrodibenzo(b,f)thiepin-10-yl)-4-methylpiperazine |
Piperazine, 1-(8-chloro-10,11-dihydrodibenzo(b,f)thiepin-10-yl)-4-methyl- |
Clotepin; Clothepin; Octoclothepin; OctoclothepineV |
Clorotepine INN |
Clorotepina |
Clorotepinum |
1-(8-chloro-10,11-dihydrodibenzob,fthiepin-10-yl)-4-methylpiperazine |
Clorotepinum INN-Latin |
Clorotepina INN-Spanish |
stearylthioglycolate |
Octoclothepin maleate |
CLOROTEPINE(-) |
CLOROTEPINE (+) |
OCTOCLOTHEPIN,(+) |
OCTOCLOTHEPIN,(-) |
Lopac0_000885 |
SCHEMBL678917 |
DTXSID7048451 |
BDBM22872 |
CHEBI:135459 |
PDSP1_001546 |
PDSP2_001530 |
AKOS005065436 |
CCG-204967 |
SDCCGSBI-0050860.P002 |
NCGC00015759-02 |
NCGC00015759-03 |
NCGC00015759-07 |
NCGC00162287-01 |
FT-0746338 |
L000790 |
Q5135148 |
BRD-A19053834-050-06-1 |
1-(3-chloro-5,6-dihydrobenzob1benzothiepin-5-yl)-4-methyl-piperazine |
1-(3-chloro-5,6-dihydrobenzob1benzothiepin-5-yl)-4-methyl-piperazine;maleate |
1-{6-chloro-2-thiatricyclo9.4.0.0^{3,8}pentadeca-1(15),3(8),4,6,11,13-hexaen-9-yl}-4-methylpiperazine |
Experimental Data
Clorotepine
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Drosophila melanogaster | 200.000000000000000 | umol/L | 44.010000000000000 | 50.280000000000000 | 14.250000000000000 | S | MALES | 33008901 | Active | ||||
| Drosophila melanogaster | 20.000000000000000 | umol/L | 48.860000000000000 | 49.900000000000000 | 2.139000000000000 | NS | FEMALES | 33008901 | Inactive | ||||
| Drosophila melanogaster | 20.000000000000000 | umol/L | 52.830000000000000 | 57.260000000000000 | 8.380000000000000 | S | FEMALES | 33008901 | Active | ||||
| Drosophila melanogaster | 200.000000000000000 | umol/L | 47.160000000000000 | 45.350000000000000 | -3.840000000000000 | NS | MALES | 33008901 | Inactive | ||||
| Caenorhabditis elegans | 13.000000000000000 | umol/L | 38.000000000000000 | S | N2 | 24134630 | Active |
Experimental Data Visualization
Clorotepine
Statistics Data
Clorotepine
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 38.000000000000000 | 1 | 1 | |
| Drosophila melanogaster | 14.250000000000000 | 1 | 4 |
Statistics Data Visualization
Clorotepine
