Compound Summary
CYTARABINE HYDROCHLORIDE
Compound Information
CYTARABINE HYDROCHLORIDE
Compound Name: | CYTARABINE HYDROCHLORIDE |
Compound CID: | 6252 |
Synonyms: | CYTARABINE HYDROCHLORIDE 69-74-9 Cytosine arabinoside hydrochloride Cytarabine HCl 1-beta-D-Arabinofuranosylcytosine hydrochloride More... |
Iupac Name: | 4-amino-1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one;hydrochloride |
InChI: | InChI=1S/C9H13N3O5.ClH/c10-5-1-2-12(9(16)11-5)8-7(15)6(14)4(3-13)17-8;/h1-2,4,6-8,13-15H,3H2,(H2,10,11,16);1H/t4-,6-,7+,8-;/m1./s1 |
InChIKey: | KCURWTAZOZXKSJ-JBMRGDGGSA-N |
Canonical Smiles: | C1=CN(C(=O)N=C1N)C2C(C(C(O2)CO)O)O.Cl |
Isomeric Smiles: | C1=CN(C(=O)N=C1N)[C@H]2[C@H]([C@@H]([C@H](O2)CO)O)O.Cl |
Molecular Weight: | 279.68 |
Molecular Formula: | C9H14ClN3O5 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
CYTARABINE HYDROCHLORIDE
Molecular Weight: | 279.68 |
Molecular Formula: | C9H14ClN3O5 |
Hydrogen Bond Donor Count: | 5 |
Hydrogen Bond Acceptor Count: | 5 |
Rotatable Bond Count: | 2 |
Heavy Atom Count: | 18 |
Complexity: | 383 |
Synonyms
CYTARABINE HYDROCHLORIDE
| CYTARABINE HYDROCHLORIDE | CYTARABINE HYDROCHLORIDE |
|---|---|
CYTARABINE HYDROCHLORIDE |
69-74-9 |
Cytosine arabinoside hydrochloride |
Cytarabine HCl |
1-beta-D-Arabinofuranosylcytosine hydrochloride |
Ara-C hydrochloride |
Cytarabine (hydrochloride) |
Cytosar hydrochloride |
Cytosine-1-beta-D-arabinofuranoside hydrochloride |
Cytarabine hydrochloride USAN |
U-19920A |
UNII-33K3DB6591 |
Cytosine beta-D-arabinofuranoside hydrochloride |
Arabitin hydrochloride |
Aracytin hydrochloride |
Arabinosylcytosine hydrochloride |
Aracytidine hydrochloride |
69-74-9 (HCL) |
MLS000028466 |
MFCD00012839 |
33K3DB6591 |
4-amino-1-((2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one hydrochloride |
Arabinosyl cytosine hydrochloride |
SMR000058432 |
Arabinofuranosylcytosine hydrochloride |
29363-79-9 |
Spongocytidine hydrochloride |
Cytarabine hydrochloride (USAN) |
Cytarabin hydrochloride |
AC 1075 |
CCRIS 4774 |
EINECS 200-713-9 |
C9H13N3O5.HCl |
AI3-52344 |
SR-01000075773 |
NSC-63878 |
1beta-D-Arabinofuranosylcytosine hydrochloride |
1beta-D-Arabinofuranosylcytosine monohydrochloride |
1-beta-D-Arabinofuranosylcytosine monohydrochloride |
4-amino-1-(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-ylpyrimidin-2(1H)-one hydrochloride |
Cytosine, 1-beta-D-arabinofuranosyl-, hydrochloride |
Cytosine, 1-beta-D-arabinofuranosyl-, monhydrochloride |
Cytosine, 1beta-D-arabinofuranosyl-, monohydrochloride |
Opera_ID_1542 |
DSSTox_CID_4891 |
2(1H)-Pyrimidinone, 4-amino-1-beta-D-arabinofuranosyl-, monohydrochloride |
Arabinocytidine hydrochloride |
DSSTox_RID_77571 |
DSSTox_GSID_24891 |
SCHEMBL67288 |
MLS001148147 |
MLS002207299 |
CHEMBL1256472 |
Cytosine, 1-beta-D-arabinofuranosyl-, monohydrochloride |
DTXSID5024891 |
AMY15521 |
Tox21_300488 |
Tox21_500316 |
HY-13605A |
s5582 |
1-Beta-D-Arabinofuranosylcytosine HCl |
AKOS015896936 |
AKOS015960559 |
AKOS015995277 |
CCG-221620 |
LP00316 |
CAS-69-74-9 |
NCGC00093762-01 |
NCGC00254321-01 |
NCGC00261001-01 |
AC-11705 |
AC-32195 |
BA164338 |
K172 |
1-b-D-Arabinofuranosylcytosine hydrochloride |
DB-025611 |
Cytosine-beta-D-arabinofuranose hydrochloride |
EU-0100316 |
1-(b-D-Arabinofuranosyl)cytosine hydrochloride |
A51105 |
C 6645 |
D03637 |
069C749 |
1-(beta-d-arabino-furanosyl)-cytosine hydrochloride |
SR-01000075773-1 |
Q27256279 |
Cytosine beta-D-arabinofuranoside hydrochloride, crystalline |
2(1H)-Pyrimidinone,4-amino-1-b-D-arabinofuranosyl-,hydrochloride (1:1) |
Arabinocytidine hydrochloride; Arabinosylcytosine hydrochloride; Ara-C hydrochloride |
4-Amino-1-((2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)pyrimidin-2(1H)-one hydrochloride |
4-Amino-1-((2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one hydrochloride(1:x) |
4-amino-1-(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-ylpyrimidin-2-one;hydrochloride |
Experimental Data
CYTARABINE HYDROCHLORIDE
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33.000000000000000 | umol/L | 8.000000000000000 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
CYTARABINE HYDROCHLORIDE
Statistics Data
CYTARABINE HYDROCHLORIDE
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 8.000000000000000 | 1 | 1 |
Statistics Data Visualization
CYTARABINE HYDROCHLORIDE
