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Compound Summary

CORTISONE ACETATE

Compound Information

CORTISONE ACETATE

Compound Name:	CORTISONE ACETATE
Compound CID:	5745
Synonyms:	CORTISONE ACETATE Cortisone 21-acetate 50-04-4 Cortone acetate Incortin More...
Iupac Name:	[2-[(8S,9S,10R,13S,14S,17R)-17-hydroxy-10,13-dimethyl-3,11-dioxo-1,2,6,7,8,9,12,14,15,16-decahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate
InChI:	InChI=1S/C23H30O6/c1-13(24)29-12-19(27)23(28)9-7-17-16-5-4-14-10-15(25)6-8-21(14,2)20(16)18(26)11-22(17,23)3/h10,16-17,20,28H,4-9,11-12H2,1-3H3/t16-,17-,20+,21-,22-,23-/m0/s1
InChIKey:	ITRJWOMZKQRYTA-RFZYENFJSA-N
Canonical Smiles:	CC(=O)OCC(=O)C1(CCC2C1(CC(=O)C3C2CCC4=CC(=O)CCC34C)C)O
Isomeric Smiles:	CC(=O)OCC(=O)[C@]1(CC[C@@H]2[C@@]1(CC(=O)[C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)C)O
Molecular Weight:	402.5
Molecular Formula:	C23H30O6

Compound Structure

2D Structure:

3D Structure:

Computed Properties

CORTISONE ACETATE

Molecular Weight:	402.5
Molecular Formula:	C23H30O6
Hydrogen Bond Donor Count:	1
Hydrogen Bond Acceptor Count:	6
Rotatable Bond Count:	4
Heavy Atom Count:	29
Complexity:	827

Synonyms

CORTISONE ACETATE

CORTISONE ACETATE	CORTISONE ACETATE
CORTISONE ACETATE	Cortisone 21-acetate
50-04-4	Cortone acetate
Incortin	Biocort acetate
Artriona	Cortadren
Scheroson	Cortisyl
Adreson	Irisone acetate
Cortelan	Cortistab
Ricortex	Cortogen acetate
Compound E acetate	Pregn-4-ene-3,11,20-trione, 21-(acetyloxy)-17-hydroxy-
Cortisone monoacetate	NSC 49420
Cortisone, 21-acetate	Cortilen
UNII-883WKN7W8X	11-Dehydro-17-hydroxycorticosterone-21-acetate
11-Dehydro-17-hydroxycorticosterone acetate	17,21-Dihydroxypregn-4-ene-3,11,20-trione 21-acetate
883WKN7W8X	CHEBI:3897
Pregn-4-ene-3,11,20-trione, 17,21-dihydroxy-, 21-acetate	Cortisone (acetate)
MFCD00003609	NSC-49420
NCGC00021191-07	DSSTox_CID_2858
DSSTox_RID_76761	DSSTox_GSID_22858
17-Hydroxy-3,11,20-trioxopregn-4-en-21-yl acetate	21-Acetoxy-4-pregnen-17alpha-ol-3,11,20-trione
17,21-Dihydroxypregn-4-ene-3,11,20-trione-21-acetate	17alpha,21-dihydroxypregn-4-ene-3,11,20-trione acetate
CAS-50-04-4	2-(8S,9S,10R,13S,14S,17R)-17-hydroxy-10,13-dimethyl-3,11-dioxo-1,2,6,7,8,9,12,14,15,16-decahydrocyclopentaaphenanthren-17-yl-2-oxoethyl acetate
2-((1S,10S,11S,15S,2R,14R)-14-hydroxy-2,15-dimethyl-5,17-dioxotetracyclo8.7.0 .0<2,7>.0<11,15>heptadec-6-en-14-yl)-2-oxoethyl acetate	2-((8S,9S,10R,13S,14S,17R)-17-hydroxy-10,13-dimethyl-3,11-dioxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopentaaphenanthren-17-yl)-2-oxoethyl acetate
SMR000059124	CCRIS 3661
Cortisone acetate (Cortone)	EINECS 200-006-5
cortisoneacetate	Cortisone acetate USP:JAN
Acetate cortisone	Cortisyl artriona
component of Neosone	Neosone (Salt/Mix)
21-(Acetyloxy)-17-hydroxypregn-4-ene-3,11,20-trione	Cortisone-21-acetate
21-Acetoxy-17,alpha-hydroxy-3,11,20-triketopregnene-4	21-Acetoxy-17,alpha-hydroxypregn-4-ene-3,11,20-trione
Cortone acetate (TN)	4-Pregnene-17,alpha,21-diol-3,11,20-trione 21-acetate
SCHEMBL4501	CHEMBL1650
Lopac0_000271	MLS000069478
MLS002207136	MLS002548859
ARONIS24358	Cortisone acetate (JP17/USP)
DTXSID0022858	Cortisone 21-acetate, >=99%
HMS2235D24	HMS3259N19
HMS3260H04	BCP08487
NSC49420	ZINC3875334
Tox21_113482	Tox21_500271
BDBM50455157	HY-17461A
LMST02030120	SBB080776
AKOS005267225	Tox21_113482_1
AC-6827	CCG-204366
CS-1742	DB01380
LP00271	MCULE-8390750975
NC00677	SDCCGSBI-0050259.P002
NCGC00021191-03	NCGC00021191-06
NCGC00021191-08	NCGC00021191-09
NCGC00021191-16	NCGC00260956-01
2-(8S,9S,10R,13S,14S,17R)-17-hydroxy-10,13-dimethyl-3,11-dioxo-1,2,6,7,8,9,12,14,15,16-decahydrocyclopentaaphenanthren-17-yl-2-oxo-ethyl acetate	AS-13692
ST075179	EU-0100271
S2559	C08173
C90609	D00973
J10115	AB00384283-08
AB00384283_09	003C609
W-105993	BRD-K86161929-001-13-3
Pregn-4-ene-3,20-trione, 21-(acetyloxy)-17-hydroxy-	17-Hydroxy-3,11,20-trioxopregn-4-en-21-yl acetate #
21-Acetoxy-17.alpha.-hydroxy-3,11,20-triketopregnene-4	21-Acetoxy-17.alpha.-hydroxypregn-4-ene-3,11,20-trione
4-Pregnen-17.alpha.,21-diol-3,11,20-trione 21-acetate	4-Pregnene-17alpha,21-diol-3,11,20-trione 21-acetate
Pregn-4-ene-3,20-trione, 17,21-dihydroxy-, 21-acetate	17alpha,21-Dihydroxy-4-pregnene-3,11,20-trione 21-acetate
4-Pregnene-17.alpha.,21-diol-3,11,20-trione 21-acetate	Cortisone acetate, European Pharmacopoeia (EP) Reference Standard
Cortisone acetate, United States Pharmacopeia (USP) Reference Standard	Cortisone Acetate, Pharmaceutical Secondary Standard; Certified Reference Material

Experimental Data

CORTISONE ACETATE

Species	Dose	Unit	Control(Avg days)	Treatment(Avg days)	Avg/Med Lifespan Change(%)	Control(Max days)	Treatment(Max days)	Max Lifespan Change(%)	Significant	Strain	Gender	PubMed	Avg/Med Lifespan Change tab
Caenorhabditis elegans	33.000000000000000	umol/L			-1.000000000000000				NS	N2		24134630	Inactive

Experimental Data Visualization

CORTISONE ACETATE

Statistics Data

CORTISONE ACETATE

Species	Avg/Med Lifespan Change(%)	Max Lifespan Change(%)	Count Reference	Count Data point
Caenorhabditis elegans	-1.000000000000000		1	1

Statistics Data Visualization

CORTISONE ACETATE

Compound Name:

CORTISONE ACETATE

Compound CID:

5745

Synonyms:

CORTISONE ACETATE Cortisone 21-acetate 50-04-4 Cortone acetate Incortin More...

Iupac Name:

[2-[(8S,9S,10R,13S,14S,17R)-17-hydroxy-10,13-dimethyl-3,11-dioxo-1,2,6,7,8,9,12,14,15,16-decahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate

InChI:

InChI=1S/C23H30O6/c1-13(24)29-12-19(27)23(28)9-7-17-16-5-4-14-10-15(25)6-8-21(14,2)20(16)18(26)11-22(17,23)3/h10,16-17,20,28H,4-9,11-12H2,1-3H3/t16-,17-,20+,21-,22-,23-/m0/s1

InChIKey:

ITRJWOMZKQRYTA-RFZYENFJSA-N

Canonical Smiles:

CC(=O)OCC(=O)C1(CCC2C1(CC(=O)C3C2CCC4=CC(=O)CCC34C)C)O

Isomeric Smiles:

CC(=O)OCC(=O)[C@]1(CC[C@@H]2[C@@]1(CC(=O)[C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)C)O

Molecular Weight:

402.5

Molecular Formula:

C23H30O6

Molecular Weight:

402.5

Molecular Formula:

C23H30O6

Hydrogen Bond Donor Count:

1

Hydrogen Bond Acceptor Count:

6

Rotatable Bond Count:

4

Heavy Atom Count:

29

Complexity:

827

CORTISONE ACETATE

Cortisone 21-acetate

50-04-4

Cortone acetate

Incortin

Biocort acetate

Artriona

Cortadren

Scheroson

Cortisyl

Adreson

Irisone acetate

Cortelan

Cortistab

Ricortex

Cortogen acetate

Compound E acetate

Pregn-4-ene-3,11,20-trione, 21-(acetyloxy)-17-hydroxy-

Cortisone monoacetate

NSC 49420

Cortisone, 21-acetate

Cortilen

UNII-883WKN7W8X

11-Dehydro-17-hydroxycorticosterone-21-acetate

11-Dehydro-17-hydroxycorticosterone acetate

17,21-Dihydroxypregn-4-ene-3,11,20-trione 21-acetate

883WKN7W8X

CHEBI:3897

Pregn-4-ene-3,11,20-trione, 17,21-dihydroxy-, 21-acetate

Cortisone (acetate)

MFCD00003609

NSC-49420

NCGC00021191-07

DSSTox_CID_2858

DSSTox_RID_76761

DSSTox_GSID_22858

17-Hydroxy-3,11,20-trioxopregn-4-en-21-yl acetate

21-Acetoxy-4-pregnen-17alpha-ol-3,11,20-trione

17,21-Dihydroxypregn-4-ene-3,11,20-trione-21-acetate

17alpha,21-dihydroxypregn-4-ene-3,11,20-trione acetate

CAS-50-04-4

2-(8S,9S,10R,13S,14S,17R)-17-hydroxy-10,13-dimethyl-3,11-dioxo-1,2,6,7,8,9,12,14,15,16-decahydrocyclopentaaphenanthren-17-yl-2-oxoethyl acetate

2-((1S,10S,11S,15S,2R,14R)-14-hydroxy-2,15-dimethyl-5,17-dioxotetracyclo8.7.0 .0<2,7>.0<11,15>heptadec-6-en-14-yl)-2-oxoethyl acetate

2-((8S,9S,10R,13S,14S,17R)-17-hydroxy-10,13-dimethyl-3,11-dioxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopentaaphenanthren-17-yl)-2-oxoethyl acetate

SMR000059124

CCRIS 3661

CORTISONE ACETATE

Cortisone 21-acetate

50-04-4

Cortone acetate

Incortin

More...