Compound Summary
CICLOPIROX
Compound Information
CICLOPIROX
Compound Name: | CICLOPIROX |
Compound CID: | 2749 |
Synonyms: | CICLOPIROX 29342-05-0 Loprox HOE 296b Ciclopiroxum More... |
Iupac Name: | 6-cyclohexyl-1-hydroxy-4-methylpyridin-2-one |
InChI: | InChI=1S/C12H17NO2/c1-9-7-11(13(15)12(14)8-9)10-5-3-2-4-6-10/h7-8,10,15H,2-6H2,1H3 |
InChIKey: | SCKYRAXSEDYPSA-UHFFFAOYSA-N |
Canonical Smiles: | CC1=CC(=O)N(C(=C1)C2CCCCC2)O |
Isomeric Smiles: | CC1=CC(=O)N(C(=C1)C2CCCCC2)O |
Molecular Weight: | 207.27 |
Molecular Formula: | C12H17NO2 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
CICLOPIROX
Molecular Weight: | 207.27 |
Molecular Formula: | C12H17NO2 |
Hydrogen Bond Donor Count: | 1 |
Hydrogen Bond Acceptor Count: | 2 |
Rotatable Bond Count: | 1 |
Heavy Atom Count: | 15 |
Complexity: | 325 |
Synonyms
CICLOPIROX
| CICLOPIROX | CICLOPIROX |
|---|---|
CICLOPIROX |
29342-05-0 |
Loprox |
HOE 296b |
Ciclopiroxum |
Ciclopiroxum INN-Latin |
2(1H)-Pyridinone, 6-cyclohexyl-1-hydroxy-4-methyl- |
HOE-296b |
6-cyclohexyl-1-hydroxy-4-methylpyridin-2(1H)-one |
6-cyclohexyl-1-hydroxy-4-methylpyridin-2-one |
6-Cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridone |
Penlac |
6-Cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridinone |
HOE296b |
UNII-19W019ZDRJ |
Ciclopirox (Penlac) |
Loprox (TN) |
19W019ZDRJ |
Terit |
CHEBI:453011 |
29342-05-0 (free) |
Stieprox |
Ciclopirox gel |
Loprox cream |
Loprox Gel |
Ciclopirox Olamin |
Ciclopirox-Olamin |
6-cyclohexyl-4-methyl-1-oxidanyl-pyridin-2-one |
6-CYCLOHEXYL-1-HYDROXY-4-METHYL-1H-PYRIDIN-2-ONE |
MLS002153867 |
Penlac (TN) |
Ciclopirox (USP/INN) |
CNL8 |
SMR001233223 |
EINECS 249-577-2 |
Ciclodan |
Ciclopirox USAN:USP:INN:BAN |
2(1H)-Pyridone, 6-cyclohexyl-1-hydroxy-4-methyl- |
Prestwick0_000541 |
Prestwick1_000541 |
Prestwick2_000541 |
Prestwick3_000541 |
Spectrum2_000146 |
Spectrum3_000351 |
Spectrum4_000288 |
Spectrum5_000747 |
6-cyclohexyl-1-hydroxy-4-methyl-pyridin-2-one |
CHEMBL1413 |
SCHEMBL34424 |
BSPBio_000581 |
BSPBio_002041 |
KBioGR_000816 |
6-Cyclohexyl-1-hydroxy-4-methyl-2-(1H)-pyridone |
cid_38911 |
BIDD:GT0080 |
(6-Cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridone) |
SPBio_000252 |
SPBio_002502 |
BPBio1_000641 |
ZINC1145 |
Ciclopirox, >=98% (HPLC) |
DTXSID9048564 |
BDBM66087 |
GTPL11349 |
KBio3_001261 |
HMS3656I12 |
BCP28530 |
HY-B0450 |
MFCD00599441 |
s2528 |
AKOS015895717 |
AB06517 |
CCG-266632 |
DB01188 |
KS-5085 |
NCGC00017112-04 |
NCGC00017112-05 |
NCGC00017112-06 |
NCGC00017112-08 |
NCGC00017112-11 |
NCGC00178850-01 |
NCGC00178850-02 |
AC-24195 |
SBI-0206690.P002 |
AB0011605 |
DB-047566 |
HOE 296; HOE-296;Ciclopiroxum; Penlac |
1-hydroxy-4-methyl-6-cyclohexyl-2-pyridone |
FT-0602961 |
SW196923-5 |
6-cyclohexyl-1-hydroxy-4-methyl-2-pyridinone |
D03488 |
AB00053438_09 |
AB00053438_10 |
AB00053438_11 |
342C050 |
A819878 |
Q419468 |
SR-05000001589-5 |
W-106995 |
6-Cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridinone # |
BRD-K13044802-213-04-1 |
BRD-K13044802-213-09-0 |
2-aminoethanol;6-cyclohexyl-1-hydroxy-4-methyl-2-pyridone |
6-cyclohexyl-1-hydroxy-4-methyl-1,2-dihydropyridin-2-one |
Ciclopirox, European Pharmacopoeia (EP) Reference Standard |
2-aminoethanol;6-cyclohexyl-1-hydroxy-4-methyl-2-pyridinone |
2-azanylethanol;6-cyclohexyl-4-methyl-1-oxidanyl-pyridin-2-one |
Ciclopirox, United States Pharmacopeia (USP) Reference Standard |
Experimental Data
CICLOPIROX
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 0.010000000000000 | % | 21.310000000000000 | 29.980000000000000 | 0.410000000000000 | 27.000000000000000 | 39.000000000000000 | 0.440000000000000 | S | N2 | 22114686 | Active |
Experimental Data Visualization
CICLOPIROX
Statistics Data
CICLOPIROX
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 0.410000000000000 | 0.440000000000000 | 1 | 1 |
Statistics Data Visualization
CICLOPIROX
