Compound Summary
CGP 12177 HYDROCHLORIDE
Compound Information
CGP 12177 HYDROCHLORIDE
Compound Name: | CGP 12177 HYDROCHLORIDE |
Compound CID: | 11957517 |
Synonyms: | CGP 12177 HYDROCHLORIDE 64208-32-8 4-(3-(tert-butylamino)-2-hydroxypropoxy)-1H-benzodimidazol-2(3H)-one hydrochloride CGP 12177 hydochloride 4-3-(tert-butylamino)-2-hydroxypropoxy-1,3-dihydrobenzimidazol-2-one;hydrochloride More... |
Iupac Name: | 4-[3-(tert-butylamino)-2-hydroxypropoxy]-1,3-dihydrobenzimidazol-2-one;hydrochloride |
InChI: | InChI=1S/C14H21N3O3.ClH/c1-14(2,3)15-7-9(18)8-20-11-6-4-5-10-12(11)17-13(19)16-10;/h4-6,9,15,18H,7-8H2,1-3H3,(H2,16,17,19);1H |
InChIKey: | YQVFCYCTITZLSX-UHFFFAOYSA-N |
Canonical Smiles: | CC(C)(C)NCC(COC1=CC=CC2=C1NC(=O)N2)O.Cl |
Isomeric Smiles: | CC(C)(C)NCC(COC1=CC=CC2=C1NC(=O)N2)O.Cl |
Molecular Weight: | 315.79 |
Molecular Formula: | C14H22ClN3O3 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
CGP 12177 HYDROCHLORIDE
Molecular Weight: | 315.79 |
Molecular Formula: | C14H22ClN3O3 |
Hydrogen Bond Donor Count: | 5 |
Hydrogen Bond Acceptor Count: | 4 |
Rotatable Bond Count: | 6 |
Heavy Atom Count: | 21 |
Complexity: | 343 |
Synonyms
CGP 12177 HYDROCHLORIDE
| CGP 12177 HYDROCHLORIDE | CGP 12177 HYDROCHLORIDE |
|---|---|
CGP 12177 HYDROCHLORIDE |
64208-32-8 |
4-(3-(tert-butylamino)-2-hydroxypropoxy)-1H-benzodimidazol-2(3H)-one hydrochloride |
CGP 12177 hydochloride |
4-3-(tert-butylamino)-2-hydroxypropoxy-1,3-dihydrobenzimidazol-2-one;hydrochloride |
81047-99-6 |
(+/-)-CGP-12177A hydrochloride |
SR-01000075262 |
EU-0100372 |
MLS000859977 |
SCHEMBL4538049 |
CHEMBL1256864 |
DTXSID00474681 |
(y)-CGP-12177A hydrochloride |
(?)-CGP-12177A hydrochloride |
Tox21_500372 |
AKOS024456407 |
CCG-221676 |
LP00372 |
NCGC00093806-01 |
NCGC00261057-01 |
SMR000326836 |
(+/-)-CGP-12177A |
C-125 |
1,3-dihydro-2H-benzimidazol-2-one hydrochloride |
SR-01000075262-1 |
SR-01000075262-3 |
( inverted question mark)-CGP-12177A hydrochloride |
(+/-)-CGP-12177A, >=98% (HPLC), solid |
4-4-(1,1-Dimethylethyl)amino-2-hydroxypropoxy- |
(+/-)-4-3-(1,1-dimethylethyl)amino-2-hydroxypropoxy-1,3-dihydro-2h-benzimidazole-2-one hydrochloride |
4-3-(1,1-Dimethylethyl)amino2-hydroxypropoxy-1,3-dihydro-2H-benzimidazol-2-one hydrochloride |
Experimental Data
CGP 12177 HYDROCHLORIDE
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33.000000000000000 | umol/L | 7.000000000000000 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
CGP 12177 HYDROCHLORIDE
Statistics Data
CGP 12177 HYDROCHLORIDE
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 7.000000000000000 | 1 | 1 |
Statistics Data Visualization
CGP 12177 HYDROCHLORIDE
