Compound Summary
CEFOTAXIME SODIUM
Compound Information
CEFOTAXIME SODIUM
Compound Name: | CEFOTAXIME SODIUM |
Compound CID: | 10695961 |
Synonyms: | CEFOTAXIME SODIUM 64485-93-4 CEFOTAXIME SODIUM SALT Sodium cefotaxime HR 756 More... |
Iupac Name: | sodium;(6R,7R)-3-(acetyloxymethyl)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate |
InChI: | InChI=1S/C16H17N5O7S2.Na/c1-6(22)28-3-7-4-29-14-10(13(24)21(14)11(7)15(25)26)19-12(23)9(20-27-2)8-5-30-16(17)18-8;/h5,10,14H,3-4H2,1-2H3,(H2,17,18)(H,19,23)(H,25,26);/q;+1/p-1/b20-9-;/t10-,14-;/m1./s1 |
InChIKey: | AZZMGZXNTDTSME-JUZDKLSSSA-M |
Canonical Smiles: | CC(=O)OCC1=C(N2C(C(C2=O)NC(=O)C(=NOC)C3=CSC(=N3)N)SC1)C(=O)[O-].[Na+] |
Isomeric Smiles: | CC(=O)OCC1=C(N2[C@@H]([C@@H](C2=O)NC(=O)/C(=N\OC)/C3=CSC(=N3)N)SC1)C(=O)[O-].[Na+] |
Molecular Weight: | 477.5 |
Molecular Formula: | C16H16N5NaO7S2 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
CEFOTAXIME SODIUM
Molecular Weight: | 477.5 |
Molecular Formula: | C16H16N5NaO7S2 |
Hydrogen Bond Donor Count: | 2 |
Hydrogen Bond Acceptor Count: | 12 |
Rotatable Bond Count: | 8 |
Heavy Atom Count: | 31 |
Complexity: | 839 |
Synonyms
CEFOTAXIME SODIUM
| CEFOTAXIME SODIUM | CEFOTAXIME SODIUM |
|---|---|
CEFOTAXIME SODIUM |
64485-93-4 |
CEFOTAXIME SODIUM SALT |
Sodium cefotaxime |
HR 756 |
Cefotaxime (sodium salt) |
cefotaxime |
(+)-Cefotaxime sodium salt |
RU 24756 |
C16H16N5NaO7S2 |
UNII-258J72S7TZ |
HR-756 |
MFCD00079073 |
MLS000028559 |
CHEBI:3498 |
258J72S7TZ |
Sodium 7-(2-(2-amino-4-thiazolyl)-2-methoxyiminoacetamido)cephalosporanate |
Cefotax |
Cefotaxim sodium salt |
sodium;(6R,7R)-3-(acetyloxymethyl)-7-(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetylamino-8-oxo-5-thia-1-azabicyclo4.2.0oct-2-ene-2-carboxylate |
SMR000058812 |
Tolycar |
Pretor |
sodium;(6R,7R)-3-(acetyloxymethyl)-7-(2E)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetylamino-8-oxo-5-thia-1-azabicyclo4.2.0oct-2-ene-2-carboxylic acid |
Ralopar |
Tolycor |
Zariviz |
Claforan sodium |
MLS002222330 |
CEFOTAXIME NA-SALT |
Ru-24756 |
Cefotaxime sodium salt (syn-isomer) |
SMR001307269 |
Cefotaxim sodium |
Claforan (TN) |
Prestwick_823 |
Cefotaxime sodium USAN:USP:JAN |
EINECS 264-915-9 |
Cefotaxime, Sodium Salt |
Opera_ID_1945 |
CHEMBL1010 |
SCHEMBL41092 |
Cefotaxime and dextrose 2.4% in plastic container |
Cefotaxime and dextrose 3.9% in plastic container |
MLS001077352 |
MLS001333684 |
CLAFORAN IN DEXTROSE 5% IN PLASTIC CONTAINER |
Cefotaxime sodium (JP17/USP) |
DTXSID4046991 |
CLAFORAN IN SODIUM CHLORIDE 0.9% IN PLASTIC CONTAINER |
HMS1568K20 |
HMS2095K20 |
HMS2233J21 |
HMS3260H18 |
HMS3712K20 |
AMY40166 |
HY-A0088 |
Tox21_500278 |
63527-52-6 (acid) |
s4517 |
AKOS015951272 |
CCG-220139 |
CCG-221582 |
CS-4297 |
KS-1416 |
NSC 756666 |
NCGC00093734-01 |
NCGC00093734-02 |
NCGC00260963-01 |
5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 3-((acetyloxy)methyl)-7-(((2-amino-4-thiazolyl)(methoxyimino)acetyl)amino)-8-oxo-, monosodium salt, (6R-(6alpha,7beta(Z)))- |
K035 |
SMR000653480 |
Sodium (6R,7R)-7-(2-(2-amino-4-thiazolyl)glyoxylamido)-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylate 7(sup 2)-(Z)-(O-methyloxime), acetate (ester) |
EU-0100278 |
A16005 |
C 7912 |
C08113 |
D00919 |
J10142 |
Cefadroxil, Antibiotic for Culture Media Use Only |
Q-200807 |
Cefotaxime sodium salt, potency: 916-964 mug per mg |
Cefotaxime sodium, European Pharmacopoeia (EP) Reference Standard |
Cefotaxime sodium salt, plant cell culture tested, BioReagent, powder |
Cefotaxime sodium, United States Pharmacopeia (USP) Reference Standard |
Cefotaxime for peak identification, European Pharmacopoeia (EP) Reference Standard |
5-Thia-1-azabicyclo4.2.0oct-2-ene-2-carboxylic acid, 3-(acetyloxy)methyl-7-(2-amino-4-thiazolyl)(methoxyimino)acetylamino-8-oxo, monosodium salt, 6R-6alpha,7 beta (Z)- |
SODIUM (6R,7R)-3-(ACETOXYMETHYL)-7-((E)-2-(2-AMINOTHIAZOL-4-YL)-2-(METHOXYIMINO)ACETAMIDO)-8-OXO-5-THIA-1-AZABICYCLO4.2.0OCT-2-ENE-2-CARBOXYLATE |
sodium (6R,7R)-3-(acetoxymethyl)-7-{(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetylamino}-8-oxo-5-thia-1-azabicyclo4.2.0oct-2-ene-2-carboxylate |
Sodium (6R,7R)-7-2-(2-amino-4-thiazolyl)glyoxylamido-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo4.2.0oct-2-ene-2-carboxylate 72-(Z)-(O-methyloxime), acetate (ester) |
Sodium (6R-(6alpha,7beta(Z)))-3-(acetoxymethyl)-7-((2-aminothiazol-4-yl)(methoxyimino)acetamido)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylate |
sodium 3-(acetoxymethyl)-7beta-{(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetylamino}-3,4-didehydrocepham-4-carboxylate |
Experimental Data
CEFOTAXIME SODIUM
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33.000000000000000 | umol/L | 7.000000000000000 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
CEFOTAXIME SODIUM
Statistics Data
CEFOTAXIME SODIUM
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 7.000000000000000 | 1 | 1 |
Statistics Data Visualization
CEFOTAXIME SODIUM
