Compound Summary
Brivudine
Compound Information
Brivudine
Compound Name: | Brivudine |
Compound CID: | 446727 |
Synonyms: | Brivudine 69304-47-8 BVDU (E)-5-(2-Bromovinyl)-2-deoxyuridine Brivudin More... |
Iupac Name: | 5-[(E)-2-bromoethenyl]-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione |
InChI: | InChI=1S/C11H13BrN2O5/c12-2-1-6-4-14(11(18)13-10(6)17)9-3-7(16)8(5-15)19-9/h1-2,4,7-9,15-16H,3,5H2,(H,13,17,18)/b2-1+/t7-,8+,9+/m0/s1 |
InChIKey: | ODZBBRURCPAEIQ-PIXDULNESA-N |
Canonical Smiles: | C1C(C(OC1N2C=C(C(=O)NC2=O)C=CBr)CO)O |
Isomeric Smiles: | C1[C@@H]([C@H](O[C@H]1N2C=C(C(=O)NC2=O)/C=C/Br)CO)O |
Molecular Weight: | 333.13 |
Molecular Formula: | C11H13BrN2O5 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
Brivudine
Molecular Weight: | 333.13 |
Molecular Formula: | C11H13BrN2O5 |
Hydrogen Bond Donor Count: | 3 |
Hydrogen Bond Acceptor Count: | 5 |
Rotatable Bond Count: | 3 |
Heavy Atom Count: | 19 |
Complexity: | 450 |
Synonyms
Brivudine
| Brivudine | Brivudine |
|---|---|
Brivudine |
69304-47-8 |
BVDU |
(E)-5-(2-Bromovinyl)-2-deoxyuridine |
Brivudin |
Helpin |
Bromovinyldeoxyuridine |
Zostex |
Brivudine INN |
5-BROMOVINYLDEOXYURIDINE |
(E)-5-(2-Bromovinyl)-deoxyuridine |
UNII-2M3055079H |
Uridine, 5-(1E)-2-bromoethenyl-2-deoxy-" |
Uridine, 5-(2-bromovinyl)-2-deoxy-, (E)- |
Brivudine (INN) |
MFCD00058585 |
RP-101 |
NCGC00093656-01 |
2M3055079H |
Brivudinum |
Brivudina |
Brivudinum INN-Latin |
Brivudina INN-Spanish |
5-((E)-2-bromovinyl)-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione |
5-(E)-2-bromoethenyl-1-(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl-1,2,3,4-tetrahydropyrimidine-2,4-dione |
BVD |
C11H13BrN2O5 |
CCRIS 2831 |
uridine, 5-(1E)-2-bromoethenyl)-2-deoxy-" |
5-(2-bromovinyl)-2-deoxyuridine |
NSC 633770 |
trans-5-(2-Bromovinyl)-2-deoxyuridine |
Bridic |
Brivox |
Zerpex |
BrVdUrd |
NSC633770 |
NSC-633770 |
RP101 |
5-(E)-(2-bromovinyl)-2-deoxyuridine" |
Uridine, 5-(2-bromoethenyl)-2-deoxy-, (E)- |
BV-dUrd |
Zostex (TN) |
(E)-5-(2-Bromovinyl)-2-deoxyuridine |
DSSTox_CID_25755 |
DSSTox_RID_81098 |
DSSTox_GSID_45755 |
Lopac0_000175 |
SCHEMBL99350 |
CHEMBL31634 |
SCHEMBL141408 |
(E)-5-(2-Bromovinyl)-dUrd |
DTXSID0045755 |
ZINC3653378 |
Tox21_111213 |
BDBM50366681 |
s5009 |
UA-618 |
ZB0745 |
e-5-(2-bromovinyl)-2-deoxyuridine |
AKOS015833980 |
CCG-204270 |
CS-6292 |
DB03312 |
LP00175 |
SDCCGSBI-0050163.P002 |
NCGC00093656-02 |
5-(E)-2-bromoethenyl-1-(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-ylpyrimidine-2,4-dione |
5-(E)-2-bromovinyl-1-(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-ylpyrimidine-2,4-dione |
AS-35234 |
HY-13578 |
5-(E)-2-bromoethenyl-2-deoxyuridine |
CAS-69304-47-8 |
A-176 |
B3404 |
EU-0100175 |
X7276 |
B 9647 |
D07249 |
Q904107 |
SR-01000075726 |
J-700153 |
SR-01000075726-1 |
Experimental Data
Brivudine
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33.000000000000000 | umol/L | -10.000000000000000 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
Brivudine
Statistics Data
Brivudine
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -10.000000000000000 | 1 | 1 |
Statistics Data Visualization
Brivudine
