Compound Summary
Antimycin A
Compound Information
Antimycin A
Compound Name: | Antimycin A |
Compound CID: | 14957 |
Synonyms: | Antimycin A Antimycin A1b Antipiricullin Fintrol Virosin More... |
Iupac Name: | [(2R,3S,6S,7R,8R)-3-[(3-formamido-2-hydroxybenzoyl)amino]-8-hexyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl] 3-methylbutanoate |
InChI: | InChI=1S/C28H40N2O9/c1-6-7-8-9-11-20-25(39-22(32)14-16(2)3)18(5)38-28(36)23(17(4)37-27(20)35)30-26(34)19-12-10-13-21(24(19)33)29-15-31/h10,12-13,15-18,20,23,25,33H,6-9,11,14H2,1-5H3,(H,29,31)(H,30,34)/t17-,18+,20-,23+,25+/m1/s1 |
InChIKey: | UIFFUZWRFRDZJC-SBOOETFBSA-N |
Canonical Smiles: | CCCCCCC1C(C(OC(=O)C(C(OC1=O)C)NC(=O)C2=C(C(=CC=C2)NC=O)O)C)OC(=O)CC(C)C |
Isomeric Smiles: | CCCCCC[C@@H]1[C@H]([C@@H](OC(=O)[C@H]([C@H](OC1=O)C)NC(=O)C2=C(C(=CC=C2)NC=O)O)C)OC(=O)CC(C)C |
Molecular Weight: | 548.6 |
Molecular Formula: | C28H40N2O9 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
Antimycin A
Molecular Weight: | 548.6 |
Molecular Formula: | C28H40N2O9 |
Hydrogen Bond Donor Count: | 3 |
Hydrogen Bond Acceptor Count: | 9 |
Rotatable Bond Count: | 12 |
Heavy Atom Count: | 39 |
Complexity: | 849 |
Synonyms
Antimycin A
| Antimycin A | Antimycin A |
|---|---|
Antimycin A |
Antimycin A1b |
Antipiricullin |
Fintrol |
Virosin |
antimycin A1 |
Antimycin-A |
Caswell No. 052B |
1397-94-0 |
CCRIS 924 |
HSDB 6417 |
UNII-75G3NMU1TS |
EPA Pesticide Chemical Code 006314 |
116095-18-2 |
75G3NMU1TS |
CHEMBL211501 |
CHEBI:22584 |
(2R,3S,6S,7R,8R)-3-(3-formamido-2-hydroxybenzoyl)amino-8-hexyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl 3-methylbutanoate |
642-15-9 |
(2R,3S,6S,7R,8R)-3-(3-formamido-2-hydroxybenzoyl)amino-8-hexyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl 3-methylbutanoate |
(2r,3s,6s,7r,8r)-3-(3-Formamido-2-Oxidanyl-Phenyl)carbonylamino-8-Hexyl-2,6-Dimethyl-4,9-Bis(Oxidanylidene)-1,5-Dioxonan-7-Yl 3-Methylbutanoate |
SR-05000002233 |
UNII-8S75R39Y6J |
SCHEMBL218354 |
CHEBI:2762 |
DTXSID3058668 |
8S75R39Y6J |
AIDS032154 |
ZINC5224254 |
BDBM50191588 |
AKOS015889205 |
BCP9000305 |
CCG-208457 |
VA10306 |
NCGC00017338-02 |
NCGC00017338-03 |
NCGC00017338-04 |
NCGC00017338-05 |
NCGC00142516-01 |
NCGC00142516-02 |
NCGC00142516-03 |
ST057184 |
HY-107406 |
CS-0028420 |
SR-05000002233-2 |
SR-05000002233-3 |
UNII-8771CCP8LT component UIFFUZWRFRDZJC-SBOOETFBSA-N |
UNII-8S75R39Y6J component UIFFUZWRFRDZJC-SBOOETFBSA-N |
(3S,6S,2R,7R,8R)-3-(3-carbonylamino-2-hydroxyphenyl)carbonylamino-8-hexyl-2, 6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl 3-methylbutanoate |
(2R,3S,6S,7R,8R)-3-(3-formamido-2-hydroxy-benzoyl)amino-8-hexyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl 3-methylbutanoate |
3-Methylbutanoic acid 3-3-(formylamino)-2-hydroxybenzoylamino-8-hexyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl ester |
AWB |
Butanoic acid, 2(or3)-methyl-,(2R,3S,6S,7R,8R)-3-3-(formylamino)-2-hydroxybenzoylamino-8-hexyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-ylester (9CI) |
Butanoic acid, 3-methyl-, 3-((3-(formylamino)-2-hydroxybenzoyl)amino)-8-hexyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl ester, (2R-(2R*,3S*,6S*,7R*,8R*))- |
isovaleric acid 8-ester with 3-formamido-N-(7-hexyl-8-hydroxy-4,9-dimethyl-2,6-dioxo-1,5-dioxonan-3-yl)salicylamide |
Experimental Data
Antimycin A
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Drosophila melanogaster | 20.000000000000000 | umol/L | 45.440000000000000 | 22.600000000000000 | -50.260000000000000 | NS | FEMALES | 33008901 | Inactive | ||||
| Drosophila melanogaster | 200.000000000000000 | umol/L | 44.800000000000000 | 9.735000000000000 | -78.270000000000000 | NS | MALES | 33008901 | Inactive | ||||
| Caenorhabditis elegans | 100.000000000000000 | umol/L | 17.080000000000000 | 9.009000000000000 | -47.240000000000000 | NS | N2 | 33008901 | Inactive | ||||
| Caenorhabditis elegans | 10.000000000000000 | umol/L | 15.550000000000000 | 5.611000000000000 | -63.910000000000000 | NS | N2 | 33008901 | Inactive | ||||
| Drosophila melanogaster | 200.000000000000000 | umol/L | 44.010000000000000 | 44.440000000000000 | 0.986000000000000 | NS | MALES | 33008901 | Inactive | ||||
| Drosophila melanogaster | 20.000000000000000 | umol/L | 48.860000000000000 | 49.210000000000000 | 0.728200000000000 | NS | FEMALES | 33008901 | Inactive |
Experimental Data Visualization
Antimycin A
Statistics Data
Antimycin A
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -47.240000000000000 | 1 | 2 | |
| Drosophila melanogaster | 0.986000000000000 | 1 | 4 |
Statistics Data Visualization
Antimycin A
