Compound Summary
AG 555
Compound Information
AG 555
Compound Name: | AG 555 |
Compound CID: | 5328770 |
Synonyms: | AG 555 133550-34-2 TYRPHOSTIN AG 555 Tyrphostin B46 Tyrphostin B-46 More... |
Iupac Name: | (E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-(3-phenylpropyl)prop-2-enamide |
InChI: | InChI=1S/C19H18N2O3/c20-13-16(11-15-8-9-17(22)18(23)12-15)19(24)21-10-4-7-14-5-2-1-3-6-14/h1-3,5-6,8-9,11-12,22-23H,4,7,10H2,(H,21,24)/b16-11+ |
InChIKey: | GSQOBTOAOGXIFL-LFIBNONCSA-N |
Canonical Smiles: | C1=CC=C(C=C1)CCCNC(=O)C(=CC2=CC(=C(C=C2)O)O)C#N |
Isomeric Smiles: | C1=CC=C(C=C1)CCCNC(=O)/C(=C/C2=CC(=C(C=C2)O)O)/C#N |
Molecular Weight: | 322.4 |
Molecular Formula: | C19H18N2O3 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
AG 555
Molecular Weight: | 322.4 |
Molecular Formula: | C19H18N2O3 |
Hydrogen Bond Donor Count: | 3 |
Hydrogen Bond Acceptor Count: | 4 |
Rotatable Bond Count: | 6 |
Heavy Atom Count: | 24 |
Complexity: | 488 |
Synonyms
AG 555
| AG 555 | AG 555 |
|---|---|
AG 555 |
133550-34-2 |
TYRPHOSTIN AG 555 |
Tyrphostin B46 |
Tyrphostin B-46 |
ag555 |
AG-555 |
MLS000069704 |
(E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-(3-phenylpropyl)prop-2-enamide |
SMR000058519 |
CHEMBL53898 |
(E)-2-Cyano-3-(3,4-dihydroxyphenyl)-N-(3-phenylpropyl)-2-propenamide |
MFCD00209865 |
149092-34-2 |
(e)-2-cyano-3-(3,4-dihydroxyphenyl)-n-(3-phenylpropyl)acrylamide |
SR-01000000219 |
Tyrphostin AG-555 |
Tocris-0618 |
Tyrphostin deriv. 46 |
Opera_ID_732 |
Lopac-T-4818 |
Lopac0_001158 |
MLS001076316 |
SCHEMBL645290 |
SCHEMBL645291 |
BDBM4303 |
cid_5328770 |
DTXSID401017644 |
HMS2230N06 |
HMS3414I05 |
HMS3678I05 |
BCP25507 |
EX-A1470 |
ZINC2557957 |
HSCI1_000030 |
s6525 |
AKOS016368124 |
CCG-205232 |
CS-7554 |
LP01158 |
SDCCGSBI-0051125.P002 |
NCGC00016028-01 |
NCGC00016028-02 |
NCGC00016028-03 |
NCGC00016028-04 |
NCGC00016028-05 |
NCGC00016028-06 |
NCGC00016028-07 |
NCGC00016028-08 |
NCGC00021314-02 |
NCGC00021314-04 |
NCGC00021314-05 |
HY-15336 |
B6377 |
EU-0101158 |
T 4818 |
J-006402 |
SR-01000000219-2 |
SR-01000000219-4 |
BRD-K34428485-001-01-0 |
N-(3-Phenylpropyl)-3,4-dihydroxy-alpha cyanocinnamide |
2-Cyano-3-(3,4-dihydroxyphenyl)-N-(3-phenylpropyl)acrylamide |
N-(3-Phenylpropyl)-alpha-cyano-3,4-dihydroxy-trans-cinnamamide |
(2E)-2-Cyano-3-(3,4-Dihydroxyphenyl)-N-(3-Phenylpropyl)-2-Propenamide |
(2E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-(3-phenylpropyl)prop-2-enamide |
(E)-2-Cyano-3-(3,4-dihydroxyphenyl)-N-(3-phenylpropyl)- 2-propenamide |
(E)-3-3,4-bis(oxidanyl)phenyl-2-cyano-N-(3-phenylpropyl)prop-2-enamide |
2-Propenamide,2-cyano-3-(3,4-dihydroxyphenyl)-N-(3-phenylpropyl)-,(2E)- |
Tyrphostin B46, N-(3(c) yen-Phenylpropyl)-3,4-Dihydroxybenzylidenecyanoacetamide |
Experimental Data
AG 555
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33.000000000000000 | umol/L | -7.000000000000000 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
AG 555
Statistics Data
AG 555
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -7.000000000000000 | 1 | 1 |
Statistics Data Visualization
AG 555
