Compound Summary
75450-34-9
Compound Information
75450-34-9
Compound Name: | 75450-34-9 |
Compound CID: | 2688 |
Synonyms: | 75450-34-9 CGP 37157 CGP37157 CGP-37157 7-Chloro-5-(2-chlorophenyl)-1,5-dihydro-4,1-benzothiazepin-2(3H)-one More... |
Iupac Name: | 7-chloro-5-(2-chlorophenyl)-1,5-dihydro-4,1-benzothiazepin-2-one |
InChI: | InChI=1S/C15H11Cl2NOS/c16-9-5-6-13-11(7-9)15(20-8-14(19)18-13)10-3-1-2-4-12(10)17/h1-7,15H,8H2,(H,18,19) |
InChIKey: | KQEPIRKXSUIUTH-UHFFFAOYSA-N |
Canonical Smiles: | C1C(=O)NC2=C(C=C(C=C2)Cl)C(S1)C3=CC=CC=C3Cl |
Isomeric Smiles: | C1C(=O)NC2=C(C=C(C=C2)Cl)C(S1)C3=CC=CC=C3Cl |
Molecular Weight: | 324.2 |
Molecular Formula: | C15H11Cl2NOS |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
75450-34-9
Molecular Weight: | 324.2 |
Molecular Formula: | C15H11Cl2NOS |
Hydrogen Bond Donor Count: | 1 |
Hydrogen Bond Acceptor Count: | 2 |
Rotatable Bond Count: | 1 |
Heavy Atom Count: | 20 |
Complexity: | 368 |
Synonyms
75450-34-9
| 75450-34-9 | 75450-34-9 |
|---|---|
75450-34-9 |
CGP 37157 |
CGP37157 |
CGP-37157 |
7-Chloro-5-(2-chlorophenyl)-1,5-dihydro-4,1-benzothiazepin-2(3H)-one |
CHEMBL1495071 |
7-chloro-5-(2-chlorophenyl)-1,5-dihydro-4,1-benzothiazepin-2-one |
C15H11Cl2NOS |
BSPBio_001556 |
KBioGR_000276 |
KBioSS_000276 |
SCHEMBL869274 |
CHEBI:91650 |
GTPL11611 |
KBio2_000276 |
KBio2_002844 |
KBio2_005412 |
KBio3_000551 |
KBio3_000552 |
DTXSID60996899 |
Bio1_000408 |
Bio1_000897 |
Bio1_001386 |
Bio2_000276 |
Bio2_000756 |
HMS1361N18 |
HMS1791N18 |
HMS1989N18 |
HMS3267K16 |
HMS3402N18 |
HMS3412I15 |
HMS3676I15 |
HMS3867M03 |
BDBM50139422 |
CM-119 |
HSCI1_000330 |
AKOS024456390 |
IDI1_034026 |
NCGC00025008-02 |
NCGC00025008-03 |
HY-15754 |
DB-055958 |
CS-0008572 |
E0002 |
FT-0641565 |
CGP-37157, >=98% (HPLC), powder |
SR-01000597388 |
SR-01000597388-1 |
BRD-A35623999-001-02-4 |
BRD-A35623999-001-03-2 |
BRD-A35623999-001-04-0 |
CGP-37157 - CAS 75450-34-9 |
Q27163475 |
7-Chloro-5-(2-chlorophenyl)-3,5-dihydro-4,1-benzothiazepin-2-ol |
7-Chloro-5-(2-chlorophenyl)-1,5-dihydro-4,1-benzothiazepin-2 (3H)-one |
7-Chloro-5-(2-chlorophenyl)-3,5-dihydrobenzoe1,4thiazepin-2(1H)-one |
Experimental Data
75450-34-9
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 150.000000000000000 | umol/L | 16.400000000000000 | 16.600000000000000 | 1.200000000000000 | NS | N2 | 30705628 | Inactive | ||||
| Caenorhabditis elegans | 1.000000000000000 | ug | 17.000000000000000 | 19.300000000000000 | 13.400000000000000 | S | N2 | 30705628 | Active | ||||
| Caenorhabditis elegans | 0.100000000000000 | ug | 17.000000000000000 | 18.600000000000000 | 9.600000000000000 | S | N2 | 30705628 | Active | ||||
| Caenorhabditis elegans | 25.000000000000000 | umol/L | 22.600000000000000 | 22.700000000000000 | 0.600000000000000 | NS | N2 | 30705628 | Inactive | ||||
| Caenorhabditis elegans | 3.000000000000000 | ug | 22.300000000000000 | 20.900000000000000 | -6.600000000000000 | S | N2 | 30705628 | Inactive | ||||
| Caenorhabditis elegans | 50.000000000000000 | umol/L | 20.700000000000000 | 24.100000000000000 | 16.500000000000000 | S | N2 | 30705628 | Active | ||||
| Caenorhabditis elegans | 100.000000000000000 | umol/L | 18.400000000000000 | 21.000000000000000 | 14.000000000000000 | S | N2 | 30705628 | Active |
Experimental Data Visualization
75450-34-9
Statistics Data
75450-34-9
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 16.500000000000000 | 1 | 7 |
Statistics Data Visualization
75450-34-9
