Compound Summary
7,8-dihydroxyflavone
Compound Information
7,8-dihydroxyflavone
Compound Name: | 7,8-dihydroxyflavone |
Compound CID: | 1880 |
Synonyms: | 7,8-dihydroxyflavone 38183-03-8 7,8-dihydroxy-2-phenyl-4H-chromen-4-one 7,8-Dihydroxyflavone hydrate 7,8-DHF More... |
Iupac Name: | 7,8-dihydroxy-2-phenylchromen-4-one |
InChI: | InChI=1S/C15H10O4/c16-11-7-6-10-12(17)8-13(19-15(10)14(11)18)9-4-2-1-3-5-9/h1-8,16,18H |
InChIKey: | COCYGNDCWFKTMF-UHFFFAOYSA-N |
Canonical Smiles: | C1=CC=C(C=C1)C2=CC(=O)C3=C(O2)C(=C(C=C3)O)O |
Isomeric Smiles: | C1=CC=C(C=C1)C2=CC(=O)C3=C(O2)C(=C(C=C3)O)O |
Molecular Weight: | 254.24 |
Molecular Formula: | C15H10O4 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
7,8-dihydroxyflavone
Molecular Weight: | 254.24 |
Molecular Formula: | C15H10O4 |
Hydrogen Bond Donor Count: | 2 |
Hydrogen Bond Acceptor Count: | 4 |
Rotatable Bond Count: | 1 |
Heavy Atom Count: | 19 |
Complexity: | 384 |
Synonyms
7,8-dihydroxyflavone
| 7,8-dihydroxyflavone | 7,8-dihydroxyflavone |
|---|---|
7,8-dihydroxyflavone |
38183-03-8 |
7,8-dihydroxy-2-phenyl-4H-chromen-4-one |
7,8-Dihydroxyflavone hydrate |
7,8-DHF |
4H-1-Benzopyran-4-one, 7,8-dihydroxy-2-phenyl- |
7,8-Dihydroxy-flavone |
7,8-Dihydroxy-2-phenyl-chromen-4-one |
7,8-Dihydroxy-2-phenyl-4-benzopyrone |
7,8-dihydroxy-2-phenylchromen-4-one |
UNII-ADB6MA8ZV2 |
ADB6MA8ZV2 |
CHEMBL75267 |
MFCD00006836 |
7,8-Dihydroxy-2-phenyl-4H-1-benzopyran-4-one |
EINECS 253-812-4 |
BRN 0234350 |
7,8-diOH-Flavone |
Spectrum_001087 |
Spectrum2_000952 |
Spectrum3_000213 |
Spectrum4_001823 |
Spectrum5_000585 |
ACMC-1AFU3 |
8-DHF |
BSPBio_001825 |
KBioGR_002491 |
KBioSS_001567 |
SPECTRUM201315 |
5-18-04-00079 (Beilstein Handbook Reference) |
BIDD:ER0103 |
DivK1c_000371 |
SCHEMBL419316 |
SPBio_000944 |
MEGxp0_001683 |
7,8-dihydroxy-2-phenylchromone |
HMS501C13 |
KBio1_000371 |
KBio2_001567 |
KBio2_004135 |
KBio2_006703 |
KBio3_001325 |
ZINC57657 |
DTXSID00191568 |
CHEBI:140464 |
NINDS_000371 |
HMS1923A03 |
HMS3263G12 |
HMS3743I05 |
HMS3886D10 |
BCP14497 |
Tox21_501075 |
BDBM50093539 |
CCG-39038 |
DHF, 7,8- |
NSC750341 |
s8319 |
SBB000930 |
AKOS015856571 |
CS-W014088 |
HY-W013372 |
MCULE-2541416717 |
NSC 750341 |
NSC-750341 |
SDCCGMLS-0066465.P001 |
IDI1_000371 |
NCGC00095217-01 |
NCGC00095217-02 |
NCGC00095217-03 |
NCGC00095217-12 |
NCGC00178976-01 |
NCGC00261760-01 |
AC-23011 |
DS-16246 |
ST057268 |
DB-049244 |
D1916 |
FT-0639436 |
7,8-Dihydroxyflavone hydrate, >=98% (HPLC) |
C74948 |
4H-1-Benzopyran-4-one,7,8-dihydroxy-2-phenyl- |
A824039 |
SR-05000002499 |
SR-05000002499-1 |
BRD-K49535716-001-02-4 |
BRD-K49535716-001-03-2 |
Q19596931 |
2(1H)-Pentalenone, 4,5,6,6a-tetrahydro-1,3-dimethyl- |
7,8-dihydroxy-2-phenyl-chromen-4-one;7,8-Dihydroxyflavone |
Experimental Data
7,8-dihydroxyflavone
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 10.000000000000000 | umol/L | 13.890000000000000 | 14.580000000000000 | 4.970000000000000 | S | N2 | 33809299 | Active | ||||
| Caenorhabditis elegans | 25.000000000000000 | umol/L | 13.890000000000000 | 13.710000000000000 | -1.300000000000000 | NS | N2 | 33809299 | Inactive | ||||
| Caenorhabditis elegans | 100.000000000000000 | umol/L | 13.890000000000000 | 13.200000000000000 | -4.680000000000000 | S | N2 | 33809299 | Inactive | ||||
| Caenorhabditis elegans | 50.000000000000000 | umol/L | 13.890000000000000 | 13.590000000000000 | -2.160000000000000 | NS | N2 | 33809299 | Inactive |
Experimental Data Visualization
7,8-dihydroxyflavone
Statistics Data
7,8-dihydroxyflavone
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 4.970000000000000 | 1 | 4 |
Statistics Data Visualization
7,8-dihydroxyflavone
