Compound Summary
5-Methylurapidil
Compound Information
5-Methylurapidil
Compound Name: | 5-Methylurapidil |
Compound CID: | 5640 |
Synonyms: | 5-Methylurapidil 5-Methyl-urapidil 34661-85-3 Urapidil, 5-Methyl- 5 Methylurapidil More... |
Iupac Name: | 6-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propylamino]-1,3,5-trimethylpyrimidine-2,4-dione |
InChI: | InChI=1S/C21H31N5O3/c1-16-19(23(2)21(28)24(3)20(16)27)22-10-7-11-25-12-14-26(15-13-25)17-8-5-6-9-18(17)29-4/h5-6,8-9,22H,7,10-15H2,1-4H3 |
InChIKey: | HIHZDNKKIUQQSC-UHFFFAOYSA-N |
Canonical Smiles: | CC1=C(N(C(=O)N(C1=O)C)C)NCCCN2CCN(CC2)C3=CC=CC=C3OC |
Isomeric Smiles: | CC1=C(N(C(=O)N(C1=O)C)C)NCCCN2CCN(CC2)C3=CC=CC=C3OC |
Molecular Weight: | 401.5 |
Molecular Formula: | C21H31N5O3 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
5-Methylurapidil
Molecular Weight: | 401.5 |
Molecular Formula: | C21H31N5O3 |
Hydrogen Bond Donor Count: | 1 |
Hydrogen Bond Acceptor Count: | 6 |
Rotatable Bond Count: | 7 |
Heavy Atom Count: | 29 |
Complexity: | 630 |
Synonyms
5-Methylurapidil
| 5-Methylurapidil | 5-Methylurapidil |
|---|---|
5-Methylurapidil |
5-Methyl-urapidil |
34661-85-3 |
Urapidil, 5-Methyl- |
5 Methylurapidil |
UNII-1HLS600135 |
6-3-4-(2-methoxyphenyl)piperazin-1-ylpropylamino-1,3,5-trimethylpyrimidine-2,4-dione |
CHEMBL420060 |
1HLS600135 |
6-((3-(4-(2-Methoxyphenyl)-1-piperazinyl)propyl)amino)-1,3,5-trimethyl-2,4(1H,3H)-pyrimidinedione |
5Methylurapidil |
Lopac-U-101 |
Lopac0_001275 |
GTPL489 |
URAPIDIL 5-METHYL- |
MLS000860044 |
SCHEMBL6375436 |
DTXSID60956150 |
HMS2232C19 |
HMS3263P12 |
HMS3373B21 |
ZINC2012436 |
Tox21_501275 |
BDBM50033112 |
MFCD00078602 |
PDSP1_001618 |
PDSP2_001602 |
CCG-205348 |
LP01275 |
SDCCGSBI-0051241.P002 |
NCGC00016067-01 |
NCGC00016067-02 |
NCGC00016067-03 |
NCGC00016067-04 |
NCGC00016067-05 |
NCGC00016067-07 |
NCGC00094511-01 |
NCGC00094511-02 |
NCGC00094511-03 |
NCGC00261960-01 |
2,4(1H,3H)-Pyrimidinedione, 6-((3-(4-(2-methoxyphenyl)-1-piperazinyl)propyl)amino)-1,3,5-trimethyl- |
SMR000326902 |
EU-0101275 |
U-101 |
L000080 |
SR-01000075287 |
J-001436 |
J-019692 |
SR-01000075287-1 |
Q27073993 |
5-Methyl-63-4-(2-methoxyphenyl)-1-piperazinyl-propyl-amino-1,3-dimethyluracil |
5-Methyl-63-4-(o-Methoxyphenyl)-1-piperazinylpropylamino-1,3-dimethyluracil |
6-{3-4-(2-Methoxy-phenyl)-piperazin-1-yl-propylamino}-1,3,5-trimethyl-1H-pyrimidine-2,4-dione |
Experimental Data
5-Methylurapidil
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33.000000000000000 | umol/L | -3.000000000000000 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
5-Methylurapidil
Statistics Data
5-Methylurapidil
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -3.000000000000000 | 1 | 1 |
Statistics Data Visualization
5-Methylurapidil
