Compound Summary
5-Demethylnobiletin
Compound Information
5-Demethylnobiletin
Compound Name: | 5-Demethylnobiletin |
Compound CID: | 358832 |
Synonyms: | 5-Demethylnobiletin 5-O-Demethylnobiletin 2174-59-6 Demethylnobiletin 5-O-Desmethylnobiletin More... |
Iupac Name: | 2-(3,4-dimethoxyphenyl)-5-hydroxy-6,7,8-trimethoxychromen-4-one |
InChI: | InChI=1S/C20H20O8/c1-23-12-7-6-10(8-14(12)24-2)13-9-11(21)15-16(22)18(25-3)20(27-5)19(26-4)17(15)28-13/h6-9,22H,1-5H3 |
InChIKey: | DOFJNFPSMUCECH-UHFFFAOYSA-N |
Canonical Smiles: | COC1=C(C=C(C=C1)C2=CC(=O)C3=C(C(=C(C(=C3O2)OC)OC)OC)O)OC |
Isomeric Smiles: | COC1=C(C=C(C=C1)C2=CC(=O)C3=C(C(=C(C(=C3O2)OC)OC)OC)O)OC |
Molecular Weight: | 388.4 |
Molecular Formula: | C20H20O8 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
5-Demethylnobiletin
Molecular Weight: | 388.4 |
Molecular Formula: | C20H20O8 |
Hydrogen Bond Donor Count: | 1 |
Hydrogen Bond Acceptor Count: | 8 |
Rotatable Bond Count: | 6 |
Heavy Atom Count: | 28 |
Complexity: | 579 |
Synonyms
5-Demethylnobiletin
| 5-Demethylnobiletin | 5-Demethylnobiletin |
|---|---|
5-Demethylnobiletin |
5-O-Demethylnobiletin |
2174-59-6 |
Demethylnobiletin |
5-O-Desmethylnobiletin |
2-(3,4-dimethoxyphenyl)-5-hydroxy-6,7,8-trimethoxy-4H-chromen-4-one |
5-hydroxy-6,7,8,3,4-pentamethoxyflavone |
2-(3,4-dimethoxyphenyl)-5-hydroxy-6,7,8-trimethoxychromen-4-one |
UNII-OGE0V42MOT |
OGE0V42MOT |
5-Hydroxy-3,4,6,7,8-pentamethoxyflavone |
4H-1-Benzopyran-4-one, 2-(3,4-dimethoxyphenyl)-5-hydroxy-6,7,8-trimethoxy- |
5-demethyl nobiletin |
CHEMBL75978 |
SPECTRUM1505030 |
SCHEMBL1764120 |
5-Desmethoxynobiletin (incorr.) |
DTXSID60176134 |
CHEBI:175933 |
HY-N1942 |
ZINC1614079 |
1047AB |
LMPK12111479 |
MFCD08458849 |
NSC618927 |
s9421 |
AKOS016010675 |
CCG-214126 |
NSC-618927 |
NCGC00094903-01 |
AC-34652 |
AS-78590 |
NCI60_005663 |
CS-0018253 |
FT-0698018 |
A878936 |
Flavone, 5-hydroxy-3,4,6,7,8-pentamethoxy- |
SR-05000002635 |
SR-05000002635-1 |
BRD-K17726681-001-01-0 |
Q27285643 |
2-(3,4-Dimethoxyphenyl)-5-hydroxy-6,7,8-trimethoxy-4H-1-benzopyran-4-one |
Experimental Data
5-Demethylnobiletin
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 12.500000000000000 | umol/L | 16.180000000000000 | 18.500000000000000 | 14.330000000000000 | S | N2 | 32677024 | Active | ||||
| Caenorhabditis elegans | 25.000000000000000 | umol/L | 16.180000000000000 | 18.980000000000000 | 17.300000000000000 | S | N2 | 32677024 | Active | ||||
| Caenorhabditis elegans | 100.000000000000000 | umol/L | 16.180000000000000 | 17.670000000000000 | 9.200000000000000 | S | N2 | 32677024 | Active | ||||
| Caenorhabditis elegans | 50.000000000000000 | umol/L | 16.180000000000000 | 20.760000000000000 | 28.300000000000000 | S | N2 | 32677024 | Active | ||||
| Caenorhabditis elegans | 6.250000000000000 | umol/L | 16.180000000000000 | 18.050000000000000 | 11.550000000000000 | S | N2 | 32677024 | Active |
Experimental Data Visualization
5-Demethylnobiletin
Statistics Data
5-Demethylnobiletin
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 28.300000000000000 | 1 | 5 |
Statistics Data Visualization
5-Demethylnobiletin
