Compound Summary
280744-09-4
Compound Information
280744-09-4
Compound Name: | 280744-09-4 |
Compound CID: | 176158 |
Synonyms: | 280744-09-4 SB 216763 3-(2,4-Dichlorophenyl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione SB216763 SB-216763 More... |
Iupac Name: | 3-(2,4-dichlorophenyl)-4-(1-methylindol-3-yl)pyrrole-2,5-dione |
InChI: | InChI=1S/C19H12Cl2N2O2/c1-23-9-13(11-4-2-3-5-15(11)23)17-16(18(24)22-19(17)25)12-7-6-10(20)8-14(12)21/h2-9H,1H3,(H,22,24,25) |
InChIKey: | JCSGFHVFHSKIJH-UHFFFAOYSA-N |
Canonical Smiles: | CN1C=C(C2=CC=CC=C21)C3=C(C(=O)NC3=O)C4=C(C=C(C=C4)Cl)Cl |
Isomeric Smiles: | CN1C=C(C2=CC=CC=C21)C3=C(C(=O)NC3=O)C4=C(C=C(C=C4)Cl)Cl |
Molecular Weight: | 371.2 |
Molecular Formula: | C19H12Cl2N2O2 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
280744-09-4
Molecular Weight: | 371.2 |
Molecular Formula: | C19H12Cl2N2O2 |
Hydrogen Bond Donor Count: | 1 |
Hydrogen Bond Acceptor Count: | 2 |
Rotatable Bond Count: | 2 |
Heavy Atom Count: | 25 |
Complexity: | 621 |
Synonyms
280744-09-4
| 280744-09-4 | 280744-09-4 |
|---|---|
280744-09-4 |
SB 216763 |
3-(2,4-Dichlorophenyl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione |
SB216763 |
SB-216763 |
3-(2,4-dichlorophenyl)-4-(1-methylindol-3-yl)pyrrole-2,5-dione |
C19H12Cl2N2O2 |
1H-Pyrrole-2,5-dione, 3-(2,4-dichlorophenyl)-4-(1-methyl-1H-indol-3-yl)- |
CHEMBL102714 |
MFCD09753369 |
3-(2,4-dichlorophenyl)-4-(1-methyl-1H-indol-3-yl)-2,5-dihydro-1H-pyrrole-2,5-dione |
SR-01000076052 |
Tocris-1616 |
Lopac-S-3442 |
Lopac0_000934 |
SCHEMBL30251 |
cc-383 |
MLS001074894 |
BDBM8296 |
cid_176158 |
GTPL8015 |
CHEBI:91421 |
AOB5004 |
DTXSID90182349 |
EX-A291 |
SYN1075 |
BCPP000073 |
HMS2235H21 |
HMS3244K13 |
HMS3244K14 |
HMS3244L13 |
HMS3262L10 |
HMS3268I05 |
HMS3295K21 |
HMS3373J13 |
HMS3412N05 |
HMS3654K15 |
HMS3676N05 |
HMS3742M09 |
HMS3884I03 |
AMY39885 |
ZINC1493890 |
Tox21_500934 |
s1075 |
AKOS015995247 |
ACN-029378 |
CCG-101287 |
CS-0139 |
LP00934 |
PB17645 |
SDCCGSBI-0050908.P002 |
NCGC00015949-01 |
NCGC00015949-02 |
NCGC00015949-03 |
NCGC00015949-04 |
NCGC00015949-05 |
NCGC00015949-19 |
NCGC00025232-01 |
NCGC00025232-02 |
NCGC00025232-03 |
NCGC00261619-01 |
AC-32722 |
HY-12012 |
SMR000568414 |
AB0023939 |
B5716 |
EU-0100934 |
FT-0688716 |
SW219850-1 |
W5100 |
EC-000.2319 |
S 3442 |
SB 216763, >98% (HPLC) |
744D094 |
A819314 |
J-510466 |
SR-01000076052-1 |
SR-01000076052-3 |
BRD-K59184148-001-04-2 |
Q27088702 |
GSK-3 Inhibitor IV, SB-216763 - CAS 280744-09-4 |
3-(2,4-Dichloro-phenyl)-4-(1-methyl-1H-indol-3-yl)-pyrrole-2,5-dione |
3-(2,4-dichlorophenyl)-4-(1-methylindol-3-yl)pyrrole-2,5-dione;SB-216763 |
Experimental Data
280744-09-4
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33.000000000000000 | umol/L | 7.000000000000000 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
280744-09-4
Statistics Data
280744-09-4
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 7.000000000000000 | 1 | 1 |
Statistics Data Visualization
280744-09-4
