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Compound Summary

2,3-Dehydrosilybin A

Compound Information

2,3-Dehydrosilybin A

Compound Name:	2,3-Dehydrosilybin A
Compound CID:	10696082
Synonyms:	2,3-Dehydrosilybin A 25166-14-7 CHEMBL315670 DTXSID60858706 More...
Iupac Name:	3,5,7-trihydroxy-2-[(2R,3R)-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydro-1,4-benzodioxin-6-yl]chromen-4-one
InChI:	InChI=1S/C25H20O10/c1-32-17-6-11(2-4-14(17)28)24-20(10-26)33-16-5-3-12(7-18(16)34-24)25-23(31)22(30)21-15(29)8-13(27)9-19(21)35-25/h2-9,20,24,26-29,31H,10H2,1H3/t20-,24-/m1/s1
InChIKey:	BVKQRAYKLBRNIK-HYBUGGRVSA-N
Canonical Smiles:	COC1=C(C=CC(=C1)C2C(OC3=C(O2)C=C(C=C3)C4=C(C(=O)C5=C(C=C(C=C5O4)O)O)O)CO)O
Isomeric Smiles:	COC1=C(C=CC(=C1)[C@@H]2[C@H](OC3=C(O2)C=C(C=C3)C4=C(C(=O)C5=C(C=C(C=C5O4)O)O)O)CO)O
Molecular Weight:	480.4
Molecular Formula:	C25H20O10

Compound Structure

2D Structure:

3D Structure:

Computed Properties

2,3-Dehydrosilybin A

Molecular Weight:	480.4
Molecular Formula:	C25H20O10
Hydrogen Bond Donor Count:	5
Hydrogen Bond Acceptor Count:	10
Rotatable Bond Count:	4
Heavy Atom Count:	35
Complexity:	816

Synonyms

2,3-Dehydrosilybin A

2,3-Dehydrosilybin A	2,3-Dehydrosilybin A
2,3-Dehydrosilybin A	25166-14-7
CHEMBL315670	DTXSID60858706

Experimental Data

2,3-Dehydrosilybin A

Species	Dose	Unit	Control(Avg days)	Treatment(Avg days)	Avg/Med Lifespan Change(%)	Control(Max days)	Treatment(Max days)	Max Lifespan Change(%)	Significant	Strain	Gender	PubMed	Avg/Med Lifespan Change tab
Caenorhabditis elegans	10.000000000000000	umol/L							NS	N2		33683565	Inactive
Caenorhabditis elegans	10.000000000000000	umol/L			12.550000000000000				S	N2		33683565	Active
Caenorhabditis elegans	10.000000000000000	umol/L	21.250000000000000	24.670000000000000	0.160000000000000				S	N2		28039083	Active
Caenorhabditis elegans	20.000000000000000	umol/L			2.160000000000000				NS	N2		33683565	Inactive
Caenorhabditis elegans	5.000000000000000	umol/L	20.880000000000000	21.330000000000000	0.020000000000000				S	N2		28039083	Active
Caenorhabditis elegans	10.000000000000000	umol/L	20.880000000000000	23.000000000000000	0.100000000000000				S	N2		28039083	Active
Caenorhabditis elegans	5.000000000000000	umol/L			2.160000000000000				S	N2		33683565	Active
Caenorhabditis elegans	10.000000000000000	umol/L			10.150000000000000				S	N2		33683565	Active
Caenorhabditis elegans	10.000000000000000	umol/L			1.180000000000000				S	N2		33683565	Active
Caenorhabditis elegans	10.000000000000000	umol/L			5.450000000000000				NS	N2		33683565	Inactive
Caenorhabditis elegans	20.000000000000000	umol/L	20.880000000000000	21.330000000000000	0.020000000000000				NS	N2		28039083	Inactive

Experimental Data Visualization

2,3-Dehydrosilybin A

Statistics Data

2,3-Dehydrosilybin A

Species	Avg/Med Lifespan Change(%)	Max Lifespan Change(%)	Count Reference	Count Data point
Caenorhabditis elegans	12.550000000000000		2	11

Statistics Data Visualization

2,3-Dehydrosilybin A