Compound Summary
16662-46-7
Compound Information
16662-46-7
Compound Name: | 16662-46-7 |
Compound CID: | 119442 |
Synonyms: | 16662-46-7 GALLOPAMIL HYDROCHLORIDE Procorum Gallopamil (hydrochloride) Methoxyverapamil hydrochloride More... |
Iupac Name: | 5-[2-(3,4-dimethoxyphenyl)ethyl-methylamino]-2-propan-2-yl-2-(3,4,5-trimethoxyphenyl)pentanenitrile;hydrochloride |
InChI: | InChI=1S/C28H40N2O5.ClH/c1-20(2)28(19-29,22-17-25(33-6)27(35-8)26(18-22)34-7)13-9-14-30(3)15-12-21-10-11-23(31-4)24(16-21)32-5;/h10-11,16-18,20H,9,12-15H2,1-8H3;1H |
InChIKey: | OKCRIUNHEQSXFD-UHFFFAOYSA-N |
Canonical Smiles: | CC(C)C(CCCN(C)CCC1=CC(=C(C=C1)OC)OC)(C#N)C2=CC(=C(C(=C2)OC)OC)OC.Cl |
Isomeric Smiles: | CC(C)C(CCCN(C)CCC1=CC(=C(C=C1)OC)OC)(C#N)C2=CC(=C(C(=C2)OC)OC)OC.Cl |
Molecular Weight: | 521.1 |
Molecular Formula: | C28H41ClN2O5 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
16662-46-7
Molecular Weight: | 521.1 |
Molecular Formula: | C28H41ClN2O5 |
Hydrogen Bond Donor Count: | 1 |
Hydrogen Bond Acceptor Count: | 7 |
Rotatable Bond Count: | 14 |
Heavy Atom Count: | 36 |
Complexity: | 639 |
Synonyms
16662-46-7
| 16662-46-7 | 16662-46-7 |
|---|---|
16662-46-7 |
GALLOPAMIL HYDROCHLORIDE |
Procorum |
Gallopamil (hydrochloride) |
Methoxyverapamil hydrochloride |
5-((3,4-Dimethoxyphenethyl)(methyl)amino)-2-isopropyl-2-(3,4,5-trimethoxyphenyl)pentanenitrile hydrochloride |
MLS000069359 |
Methoxyverapamil (hydrochloride) |
(+/-)-Methoxyverapamil hydrochloride |
SMR000058477 |
DSSTox_CID_27844 |
DSSTox_RID_82597 |
DSSTox_GSID_47858 |
5-2-(3,4-dimethoxyphenyl)ethyl-methylamino-2-propan-2-yl-2-(3,4,5-trimethoxyphenyl)pentanenitrile;hydrochloride |
5-2-(3,4-dimethoxyphenyl)ethyl-methylamino-2-propan-2-yl-2-(3,4,5-trimethoxyphenyl)pentanenitrile;hydron;chloride |
Gallopamil HCl |
5-((3,4-Dimethoxyphenethyl)(methyl)amino)-2-isopropyl-2-(3,4,5-trimethoxyphenyl)pentanenitrile HCl |
CAS-16662-46-7 |
D 600 Hydrochloride |
NCGC00015686-05 |
EINECS 240-704-7 |
NSC 274966 |
D600, HCl |
D600; Gallopamil |
(+/-)-Methoxyverapamil, Hydrochloride |
Opera_ID_1611 |
(+/-)-Methoxyverapamil HCl |
Benzeneacetonitrile, alpha-(3-((2-(3,4-dimethoxyphenyl)ethyl)methylamino)propyl)-3,4,5-trimethoxy-alpha-(1-methylethyl)-, monohydrochloride |
C28H40N2O5.HCl |
SCHEMBL194931 |
Gallopamil hydrochloride (JAN) |
CHEMBL1256940 |
DTXSID2047858 |
(?)-Methoxyverapamil hydrochloride |
(y)-Methoxyverapamil hydrochloride |
Tox21_110196 |
Tox21_500778 |
HY-14276A |
NSC274966 |
AKOS015994622 |
Tox21_110196_1 |
CCG-222082 |
HS-0066 |
LP00778 |
NSC-274966 |
(3-Cyano-3-(3,4,5-trimethoxyphenyl)hex-6-yl)-(5,6-dimethoxyphenethyl)methylammonium chloride |
NCGC00015686-11 |
NCGC00094115-01 |
NCGC00261463-01 |
LU-30029 |
CS-0109891 |
EU-0100778 |
FT-0727258 |
FT-0772263 |
X3808 |
(+/-)-Methoxyverapamil hydrochloride, >=98% |
D01969 |
I11594 |
M 5644 |
SR-01000000018 |
J-010303 |
SR-01000000018-2 |
Q27095539 |
( inverted question mark)-Methoxyverapamil hydrochloride |
Experimental Data
16662-46-7
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33.000000000000000 | umol/L | -6.000000000000000 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
16662-46-7
Statistics Data
16662-46-7
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -6.000000000000000 | 1 | 1 |
Statistics Data Visualization
16662-46-7
