Compound Summary
154447-36-6
Compound Information
154447-36-6
Compound Name: | 154447-36-6 |
Compound CID: | 3973 |
Synonyms: | 154447-36-6 LY294002 LY 294002 LY-294002 2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one More... |
Iupac Name: | 2-morpholin-4-yl-8-phenylchromen-4-one |
InChI: | InChI=1S/C19H17NO3/c21-17-13-18(20-9-11-22-12-10-20)23-19-15(7-4-8-16(17)19)14-5-2-1-3-6-14/h1-8,13H,9-12H2 |
InChIKey: | CZQHHVNHHHRRDU-UHFFFAOYSA-N |
Canonical Smiles: | C1COCCN1C2=CC(=O)C3=C(O2)C(=CC=C3)C4=CC=CC=C4 |
Isomeric Smiles: | C1COCCN1C2=CC(=O)C3=C(O2)C(=CC=C3)C4=CC=CC=C4 |
Molecular Weight: | 307.3 |
Molecular Formula: | C19H17NO3 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
154447-36-6
Molecular Weight: | 307.3 |
Molecular Formula: | C19H17NO3 |
Hydrogen Bond Donor Count: | 0 |
Hydrogen Bond Acceptor Count: | 4 |
Rotatable Bond Count: | 2 |
Heavy Atom Count: | 23 |
Complexity: | 463 |
Synonyms
154447-36-6
| 154447-36-6 | 154447-36-6 |
|---|---|
154447-36-6 |
LY294002 |
LY 294002 |
LY-294002 |
2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one |
2-morpholino-8-phenyl-4H-chromen-4-one |
2-morpholin-4-yl-8-phenyl-4H-chromen-4-one |
UNII-31M2U1DVID |
2-morpholin-4-yl-8-phenylchromen-4-one |
2-(morpholin-4-yl)-8-phenylchromen-4-one |
15447-36-6 |
2-(morpholin-4-yl)-8-phenyl-4H-chromen-4-one |
NSC 697286 |
31M2U1DVID |
2-MORPHOLIN-4-YL-7-PHENYL-4H-CHROMEN-4-ONE |
CHEMBL98350 |
4H-1-Benzopyran-4-one, 2-(4-morpholinyl)-8-phenyl- |
CHEBI:65329 |
SF 1101 |
LY2 |
4H-1-Benzopyran-4-one,2-(4-morpholinyl)-8-phenyl- |
Ly 294002 HCl |
LY-294,002 |
2-Morpholin-4-yl-8-phenyl-chromen-4-one |
BMK1-D5 |
Lys 294002 |
4azt |
InSolution™ LY 294002 |
2-morpholino-8-phenyl-chromen-4-one |
Kinome_3543 |
Tocris-1130 |
1yi3 |
BiomolKI_000029 |
Lopac-L-9908 |
8-Phenyl-2-(morpholin-4-yl)-chromen-4-one |
BiomolKI2_000037 |
cc-58 |
CBiol_002046 |
Lopac0_000710 |
SCHEMBL94377 |
BSPBio_001223 |
KBioGR_000563 |
KBioSS_000563 |
MLS006010131 |
2-Morpholino-8-phenylchromone |
2-(4-morpholino)-8-phenyl-4H-1-benzopyran-4-one |
4H-1-Benzopyran-4-one, 2-(4-morpholinyl)-8-phenyl |
GTPL6004 |
ZINC6014 |
DTXSID6042650 |
BCBcMAP01_000117 |
BDBM12915 |
KBio2_000563 |
KBio2_003131 |
KBio2_005699 |
KBio3_001005 |
KBio3_001006 |
EX-A073 |
SYN1108 |
BCPP000177 |
Bio1_000332 |
Bio1_000821 |
Bio1_001310 |
Bio2_000442 |
Bio2_000922 |
HMS1362M05 |
HMS1792M05 |
HMS1990M05 |
HMS3229G17 |
HMS3403M05 |
HMS3649E04 |
HMS3654M21 |
AMY40921 |
BCP00195 |
HSCI1_000206 |
NSC697286 |
NSC755769 |
s1105 |
AKOS017344742 |
BCP9000880 |
CCG-100633 |
CS-0150 |
DB02656 |
NSC-697286 |
NSC-755769 |
QC-7260 |
SB10965 |
SDCCGSBI-0050688.P003 |
SF-1101 |
IDI1_002197 |
NCGC00015622-01 |
NCGC00015622-02 |
NCGC00015622-03 |
NCGC00015622-04 |
NCGC00015622-05 |
NCGC00015622-06 |
NCGC00015622-07 |
NCGC00015622-23 |
NCGC00025020-01 |
NCGC00025020-02 |
NCGC00025020-03 |
NCGC00025020-04 |
NCGC00179253-01 |
AC-30295 |
AS-16252 |
HY-10108 |
NCI60_034712 |
SMR002530642 |
AB0033714 |
LY-924002 |
FT-0660382 |
M2410 |
SW217688-2 |
X7411 |
EC-000.2341 |
2-Morpholino-8-phenyl-4-oxo-4H-1-benzopyran |
K00235 |
J-510126 |
Q4042503 |
SR-01000076245-7 |
BRD-K27305650-001-05-9 |
InSolution LY 294002 - CAS 154447-36-6 |
LY-294,002 hydrochloride, solid, >=98% (HPLC) |
LY 294002 - CAS 154447-36-6 |
4H-1-Benzopyran-4-one, 2-(4-morpholinyl)-8-phenyl- (9CI) |
H-1-Benzopyran-4-one, 2-(4-morpholinyl)-8-phenyl- (9CI) |
LY 294002; 2-(4-Morpholino)-8-phenyl-4H-1-benzopyran-4-one |
Experimental Data
154447-36-6
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 0.800000000000000 | umol/L | Unclear | N2 | 33683565 | ||||||||
| Caenorhabditis elegans | 2.400000000000000 | mM | Unclear | N2 | 33683565 | ||||||||
| Caenorhabditis elegans | 100.000000000000000 | umol/L | 23.140000000000000 | 28.090000000000000 | 20.870000000000000 | S | N2 | 26676933 | Active | ||||
| Caenorhabditis elegans | 1.600000000000000 | mM | 8.700000000000000 | NS | N2 | 33683565 | Inactive | ||||||
| Drosophila melanogaster | 5.000000000000000 | umol/L | 50.000000000000000 | 57.000000000000000 | 0.140000000000000 | 71.000000000000000 | 87.000000000000000 | 0.230000000000000 | S | Canton-S | MALES | 20017609 | Active |
| Caenorhabditis elegans | 16.000000000000000 | umol/L | 9.090000000000000 | S | N2 | 33683565 | Active | ||||||
| Drosophila melanogaster | 5.000000000000000 | umol/L | 56.000000000000000 | 64.000000000000000 | 0.140000000000000 | 86.000000000000000 | 100.000000000000000 | 0.160000000000000 | S | Canton-S | FEMALES | 20017609 | Active |
| Caenorhabditis elegans | 100.000000000000000 | umol/L | 20.870000000000000 | S | N2 | 33683565 | Active | ||||||
| Caenorhabditis elegans | 163.000000000000000 | umol/L | 25.000000000000000 | S | N2 | 33683565 | Active |
Experimental Data Visualization
154447-36-6
Statistics Data
154447-36-6
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 25.000000000000000 | 2 | 7 | |
| Drosophila melanogaster | 0.140000000000000 | 0.230000000000000 | 1 | 2 |
Statistics Data Visualization
154447-36-6
