Compound Summary
140663-38-3
Compound Information
140663-38-3
Compound Name: | 140663-38-3 |
Compound CID: | 11957580 |
Synonyms: | 140663-38-3 1-(5-Isoquinolinylsulfonyl)-3-methylpiperazine dihydrochloride Iso-H7 dihydrochloride 1-(5-ISOQUINOLINYLSULFONYL)-3-METHYL-PIPERAZINE DIHYDROCHLORIDE Iso-H-7 More... |
Iupac Name: | 5-(3-methylpiperazin-1-yl)sulfonylisoquinoline;dihydrochloride |
InChI: | InChI=1S/C14H17N3O2S.2ClH/c1-11-10-17(8-7-16-11)20(18,19)14-4-2-3-12-9-15-6-5-13(12)14;;/h2-6,9,11,16H,7-8,10H2,1H3;2*1H |
InChIKey: | YHYNDFTUZMEYNX-UHFFFAOYSA-N |
Canonical Smiles: | CC1CN(CCN1)S(=O)(=O)C2=CC=CC3=C2C=CN=C3.Cl.Cl |
Isomeric Smiles: | CC1CN(CCN1)S(=O)(=O)C2=CC=CC3=C2C=CN=C3.Cl.Cl |
Molecular Weight: | 364.3 |
Molecular Formula: | C14H19Cl2N3O2S |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
140663-38-3
Molecular Weight: | 364.3 |
Molecular Formula: | C14H19Cl2N3O2S |
Hydrogen Bond Donor Count: | 3 |
Hydrogen Bond Acceptor Count: | 5 |
Rotatable Bond Count: | 2 |
Heavy Atom Count: | 22 |
Complexity: | 434 |
Synonyms
140663-38-3
| 140663-38-3 | 140663-38-3 |
|---|---|
140663-38-3 |
1-(5-Isoquinolinylsulfonyl)-3-methylpiperazine dihydrochloride |
Iso-H7 dihydrochloride |
1-(5-ISOQUINOLINYLSULFONYL)-3-METHYL-PIPERAZINE DIHYDROCHLORIDE |
Iso-H-7 |
5-((3-METHYLPIPERAZIN-1-YL)SULFONYL)ISOQUINOLINE 2HCL |
5-(3-methylpiperazin-1-yl)sulfonylisoquinoline;dihydrochloride |
1-(5-ISOQUINOLINYLSULFONYL)-3-METHYL-PIPERAZINEDIHYDROCHLORIDE |
Iso-H-7, Dihydrochloride |
SR-01000075940 |
EU-0100662 |
1-(5-Isoquinolinesulfonyl)-3-methylpiperazine, 2HCl |
SCHEMBL1321843 |
CHEMBL1412973 |
DTXSID90474690 |
AMY16319 |
Tox21_500662 |
s6510 |
AKOS037515704 |
LP00662 |
NCGC00094024-01 |
NCGC00261347-01 |
FT-0626847 |
I 6391 |
Y13551 |
A928777 |
J-007414 |
SR-01000075940-1 |
SR-01000075940-2 |
1-(5-ISOQUINOLINYLSULFONYL)-3-METHYLPIPERAZINE 2HCl |
1-(5-Isoquinolinylsulfonyl)-3-methylpiperazine dihydrochloride (H7) |
5-((3-methylpiperazin-1-yl)sulfonyl)isoquinoline dihydrochloride |
Experimental Data
140663-38-3
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33.000000000000000 | umol/L | 3.000000000000000 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
140663-38-3
Statistics Data
140663-38-3
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 3.000000000000000 | 1 | 1 |
Statistics Data Visualization
140663-38-3
