Compound Summary
133550-35-3
Compound Information
133550-35-3
Compound Name: | 133550-35-3 |
Compound CID: | 5328771 |
Synonyms: | 133550-35-3 AG 494 Tyrphostin B48 AG-494 Tyrphostin AG 494 More... |
Iupac Name: | (E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-phenylprop-2-enamide |
InChI: | InChI=1S/C16H12N2O3/c17-10-12(8-11-6-7-14(19)15(20)9-11)16(21)18-13-4-2-1-3-5-13/h1-9,19-20H,(H,18,21)/b12-8+ |
InChIKey: | HKHOVJYOELRGMV-XYOKQWHBSA-N |
Canonical Smiles: | C1=CC=C(C=C1)NC(=O)C(=CC2=CC(=C(C=C2)O)O)C#N |
Isomeric Smiles: | C1=CC=C(C=C1)NC(=O)/C(=C/C2=CC(=C(C=C2)O)O)/C#N |
Molecular Weight: | 280.28 |
Molecular Formula: | C16H12N2O3 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
133550-35-3
Molecular Weight: | 280.28 |
Molecular Formula: | C16H12N2O3 |
Hydrogen Bond Donor Count: | 3 |
Hydrogen Bond Acceptor Count: | 4 |
Rotatable Bond Count: | 3 |
Heavy Atom Count: | 21 |
Complexity: | 446 |
Synonyms
133550-35-3
| 133550-35-3 | 133550-35-3 |
|---|---|
133550-35-3 |
AG 494 |
Tyrphostin B48 |
AG-494 |
Tyrphostin AG 494 |
Tyrphostin AG-494 |
(E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-phenylacrylamide |
alpha-Cyano-(3,4-dihydroxy)-N-phenylcinnamide |
139087-53-9 |
CHEMBL56731 |
(E)-2-CYANO-3-(3,4-DIHYDROXYPHENYL)-N-PHENYL-2-PROPENAMIDE |
(E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-phenylprop-2-enamide |
N-Phenyl-3,4-dihydroxybenzylidenecyanoacetamide |
2E-cyano-3-(3,4-dihydroxyphenyl)-N-phenyl-2-propenamide |
SR-01000075495 |
tyrphostin-AG-494 |
Tocris-0619 |
Lopac-T-4318 |
Lopac0_001147 |
MLS002172496 |
BDBM4304 |
cid_5328771 |
ZINC15335 |
DTXSID201018515 |
HMS2232N04 |
HMS3263F15 |
HMS3414I07 |
HMS3678I07 |
BCP29134 |
EX-A2591 |
Tox21_501147 |
HSCI1_000168 |
MFCD00209863 |
s6509 |
AKOS024458583 |
CCG-205221 |
LP01147 |
SDCCGSBI-0051114.P002 |
NCGC00016019-01 |
NCGC00016019-02 |
NCGC00016019-03 |
NCGC00016019-04 |
NCGC00016019-05 |
NCGC00016019-06 |
NCGC00024687-01 |
NCGC00024687-02 |
NCGC00024687-03 |
NCGC00261832-01 |
BS-15206 |
SMR001254117 |
B6378 |
EU-0101147 |
EC-000.2083 |
T 4318 |
J-006403 |
SR-01000075495-1 |
SR-01000075495-3 |
BRD-K34533029-001-01-0 |
(2E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-phenylprop-2-enamide |
2-Propenamide,2-cyano-3-(3,4-dihydroxyphenyl)-N-phenyl-,(2E)- |
Experimental Data
133550-35-3
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33.000000000000000 | umol/L | 5.000000000000000 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
133550-35-3
Statistics Data
133550-35-3
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 5.000000000000000 | 1 | 1 |
Statistics Data Visualization
133550-35-3
