Compound Summary
1001645-58-4
Compound Information
1001645-58-4
Compound Name: | 1001645-58-4 |
Compound CID: | 25232708 |
Synonyms: | 1001645-58-4 SRT1720 SRT 1720 Hydrochloride SRT1720 HCl SRT1720 xHydrochloride More... |
Iupac Name: | N-[2-[3-(piperazin-1-ylmethyl)imidazo[2,1-b][1,3]thiazol-6-yl]phenyl]quinoxaline-2-carboxamide;hydrochloride |
InChI: | InChI=1S/C25H23N7OS.ClH/c33-24(22-13-27-20-7-3-4-8-21(20)28-22)29-19-6-2-1-5-18(19)23-15-32-17(16-34-25(32)30-23)14-31-11-9-26-10-12-31;/h1-8,13,15-16,26H,9-12,14H2,(H,29,33);1H |
InChIKey: | DTGRRMPPXCRRIM-UHFFFAOYSA-N |
Canonical Smiles: | C1CN(CCN1)CC2=CSC3=NC(=CN23)C4=CC=CC=C4NC(=O)C5=NC6=CC=CC=C6N=C5.Cl |
Isomeric Smiles: | C1CN(CCN1)CC2=CSC3=NC(=CN23)C4=CC=CC=C4NC(=O)C5=NC6=CC=CC=C6N=C5.Cl |
Molecular Weight: | 506 |
Molecular Formula: | C25H24ClN7OS |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
1001645-58-4
Molecular Weight: | 506 |
Molecular Formula: | C25H24ClN7OS |
Hydrogen Bond Donor Count: | 3 |
Hydrogen Bond Acceptor Count: | 7 |
Rotatable Bond Count: | 5 |
Heavy Atom Count: | 35 |
Complexity: | 707 |
Synonyms
1001645-58-4
| 1001645-58-4 | 1001645-58-4 |
|---|---|
1001645-58-4 |
SRT1720 |
SRT 1720 Hydrochloride |
SRT1720 HCl |
SRT1720 xHydrochloride |
SRT 1720 (Hydrochloride) |
SRT1720 Hydrochloride |
N-2-3-(1-Piperazinylmethyl)imidazo2,1-bthiazol-6-ylphenyl-2-quinoxalinecarboxamide hydrochloride |
N-(2-(3-(piperazin-1-ylmethyl)imidazo2,1-bthiazol-6-yl)phenyl)quinoxaline-2-carboxamide hydrochloride |
N-2-3-(piperazin-1-ylmethyl)imidazo2,1-b1,3thiazol-6-ylphenylquinoxaline-2-carboxamide;hydrochloride |
SRT1720 xHCl |
SRT-1720 xhydrochloride |
cc-265 |
MLS006011149 |
SRT 1720 HCl |
QCR-61 |
CHEMBL4639328 |
SCHEMBL16372055 |
DTXSID80649411 |
BCP01774 |
s1129 |
AKOS025401934 |
CCG-264830 |
CS-0509 |
AC-27409 |
AS-35151 |
HY-15145 |
N-2-3-(piperazin-1-ylmethyl)imidazo2,1-b1,3thiazol-6-ylphenylquinoxaline-2-carboxamide,hydrochloride |
SMR004702924 |
AB0095210 |
A4180 |
FT-0761472 |
SW218151-2 |
A24478 |
J-000057 |
J-523315 |
N-(2-{3-(Piperazin-1-yl)methylimidazo2,1-b1,3thiazol-6-yl}phenyl)quinoxaline-2-carboxamide--hydrogen chloride (1/1) |
Experimental Data
1001645-58-4
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Mus musculus | 100.000000000000000 | mg/kg | 8.800000000000000 | NS | C57BL/6J | 24582957 | Inactive |
Experimental Data Visualization
1001645-58-4
Statistics Data
1001645-58-4
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Mus musculus | 8.800000000000000 | 1 | 1 |
Statistics Data Visualization
1001645-58-4
