Compound Summary
1,5-isoquinolinediol
Compound Information
1,5-isoquinolinediol
Compound Name: | 1,5-isoquinolinediol |
Compound CID: | 1340 |
Synonyms: | 1,5-isoquinolinediol 5154-02-9 isoquinoline-1,5-diol 1,5-Dihydroxyisoquinoline 5-HYDROXYISOQUINOLINE-1(2H)-ONE More... |
Iupac Name: | 5-hydroxy-2H-isoquinolin-1-one |
InChI: | InChI=1S/C9H7NO2/c11-8-3-1-2-7-6(8)4-5-10-9(7)12/h1-5,11H,(H,10,12) |
InChIKey: | LFUJIPVWTMGYDG-UHFFFAOYSA-N |
Canonical Smiles: | C1=CC2=C(C=CNC2=O)C(=C1)O |
Isomeric Smiles: | C1=CC2=C(C=CNC2=O)C(=C1)O |
Molecular Weight: | 161.16 |
Molecular Formula: | C9H7NO2 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
1,5-isoquinolinediol
Molecular Weight: | 161.16 |
Molecular Formula: | C9H7NO2 |
Hydrogen Bond Donor Count: | 2 |
Hydrogen Bond Acceptor Count: | 2 |
Rotatable Bond Count: | 0 |
Heavy Atom Count: | 12 |
Complexity: | 225 |
Synonyms
1,5-isoquinolinediol
| 1,5-isoquinolinediol | 1,5-isoquinolinediol |
|---|---|
1,5-isoquinolinediol |
5154-02-9 |
isoquinoline-1,5-diol |
1,5-Dihydroxyisoquinoline |
5-HYDROXYISOQUINOLINE-1(2H)-ONE |
5-Hydroxyisocarbostyril |
5-Hydroxy-1(2H)-isoquinolinone |
5-HYDROXYISOQUINOLIN-1(2H)-ONE |
5-hydroxy-2H-isoquinolin-1-one |
NSC 65585 |
CHEMBL338314 |
CHEBI:64044 |
PARP Inhibitor IV, IQD |
5-Hydroxy-1(2H)-isoquinoline |
4pnt |
NSC65585 |
Lopac-I-138 |
Lopac0_000655 |
SCHEMBL51697 |
MLS000860043 |
BDBM27501 |
DTXSID60199505 |
HMS2236H08 |
HMS3262C11 |
HMS3373F20 |
ZINC8616043 |
1(2H)-Isoquinolinone, 5-hydroxy- |
1,5-dihydroxy-1(2H)-isoquinoline |
Tox21_500655 |
MFCD00006900 |
MFCD00489140 |
NSC-65585 |
AKOS005207308 |
AKOS022636198 |
AT25381 |
CCG-204741 |
CS-W016138 |
HY-W015422 |
LP00655 |
MB01281 |
MCULE-5823570385 |
SDCCGSBI-0050634.P002 |
SMP2_000192 |
NCGC00015537-01 |
NCGC00015537-02 |
NCGC00015537-03 |
NCGC00015537-04 |
NCGC00015537-06 |
NCGC00094018-01 |
NCGC00094018-02 |
NCGC00261340-01 |
AC-10035 |
AS-57417 |
SMR000326901 |
DB-051983 |
EU-0100655 |
FT-0635564 |
I-138 |
ST50405514 |
PARP Inhibitor IV, IQD - CAS 1188540 |
A22232 |
1,5-Isoquinolinediol, >=98% (HPLC), powder |
5-HYDROXY-1,2-DIHYDROISOQUINOLIN-1-ONE |
154I029 |
SR-01000075624 |
SR-01000075624-1 |
BRD-K90230846-001-01-5 |
BRD-K90230846-001-04-9 |
Q27132988 |
F2135-0800 |
Z1255402655 |
IQD |
Experimental Data
1,5-isoquinolinediol
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 50.000000000000000 | umol/L | -7.340000000000000 | S | N2 | 30970250 | Inactive | ||||||
| Caenorhabditis elegans | 33.000000000000000 | umol/L | 0.000000000000000 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
1,5-isoquinolinediol
Statistics Data
1,5-isoquinolinediol
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 0.000000000000000 | 2 | 2 |
Statistics Data Visualization
1,5-isoquinolinediol
