Compound Summary
(-)-U-50488 HYDROCHLORIDE
Compound Information
(-)-U-50488 HYDROCHLORIDE
Compound Name: | (-)-U-50488 HYDROCHLORIDE |
Compound CID: | 9931141 |
Synonyms: | (-)-U-50488 HYDROCHLORIDE (-)-trans-(1S,2S)-U-50488 hydrochloride 114528-79-9 CHEMBL593781 (-)-trans-(1S,2S)-u-50488 Hydrochloride potent k opioid recep More... |
Iupac Name: | 2-(3,4-dichlorophenyl)-N-methyl-N-[(1S,2S)-2-pyrrolidin-1-ylcyclohexyl]acetamide;hydrochloride |
InChI: | InChI=1S/C19H26Cl2N2O.ClH/c1-22(19(24)13-14-8-9-15(20)16(21)12-14)17-6-2-3-7-18(17)23-10-4-5-11-23;/h8-9,12,17-18H,2-7,10-11,13H2,1H3;1H/t17-,18-;/m0./s1 |
InChIKey: | KGMMGVIYOHGOKQ-APTPAJQOSA-N |
Canonical Smiles: | CN(C1CCCCC1N2CCCC2)C(=O)CC3=CC(=C(C=C3)Cl)Cl.Cl |
Isomeric Smiles: | CN([C@H]1CCCC[C@@H]1N2CCCC2)C(=O)CC3=CC(=C(C=C3)Cl)Cl.Cl |
Molecular Weight: | 405.8 |
Molecular Formula: | C19H27Cl3N2O |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
(-)-U-50488 HYDROCHLORIDE
Molecular Weight: | 405.8 |
Molecular Formula: | C19H27Cl3N2O |
Hydrogen Bond Donor Count: | 1 |
Hydrogen Bond Acceptor Count: | 2 |
Rotatable Bond Count: | 4 |
Heavy Atom Count: | 25 |
Complexity: | 428 |
Synonyms
(-)-U-50488 HYDROCHLORIDE
| (-)-U-50488 HYDROCHLORIDE | (-)-U-50488 HYDROCHLORIDE |
|---|---|
(-)-U-50488 HYDROCHLORIDE |
(-)-trans-(1S,2S)-U-50488 hydrochloride |
114528-79-9 |
CHEMBL593781 |
(-)-trans-(1S,2S)-u-50488 Hydrochloride potent k opioid recep |
2-(3,4-dichlorophenyl)-N-methyl-N-(1S,2S)-2-pyrrolidin-1-ylcyclohexylacetamide;hydrochloride |
U50488 Hydrochloride |
SR-01000075483 |
SR-01000597740 |
trans-(-)-3,4-Dichloro-N-methyl-N-2-(1-pyrrolidinyl)cyclohexylbenzeneacetamide hydrochloride |
MLS000862195 |
SCHEMBL7115846 |
AOB4833 |
Tox21_501266 |
AKOS024458435 |
CCG-222570 |
LP01266 |
NCGC00094503-01 |
NCGC00261951-01 |
SMR000326958 |
NCG-C00094503-01 |
(-)-Trans-(1S,2S)-U-50488 HCl |
EU-0101266 |
U-111 |
()-trans-(1S,2S)-U-50488 hydrochloride |
SR-01000075483-1 |
SR-01000075483-2 |
SR-01000597740-1 |
SR-01000597740-2 |
SR-01000597740-3 |
trans-(1S,2S)-3,4-Dichloro-N-methyl-N-(2-1-pyrollidinylcyclohexyl)benzeneacetamide hydrochloride |
Experimental Data
(-)-U-50488 HYDROCHLORIDE
| Species | Dose | Unit | Control(Avg days) | Treatment(Avg days) | Avg/Med Lifespan Change(%) | Control(Max days) | Treatment(Max days) | Max Lifespan Change(%) | Significant | Strain | Gender | PubMed | Avg/Med Lifespan Change tab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33.000000000000000 | umol/L | 1.000000000000000 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
(-)-U-50488 HYDROCHLORIDE
Statistics Data
(-)-U-50488 HYDROCHLORIDE
| Species | Avg/Med Lifespan Change(%) | Max Lifespan Change(%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 1.000000000000000 | 1 | 1 |
Statistics Data Visualization
(-)-U-50488 HYDROCHLORIDE
