Compound Summary
Compound Information
Ro 8-4304
Compound Name: | Ro 8-4304 |
Compound CID: | 9799515 |
Synonyms: | Ro 8-4304 Ro-84304 Ro-8-4304 Ro84304 Lopac0_001043 More... |
Iupac Name: | 4-[3-[4-(4-fluorophenyl)-3,6-dihydro-2H-pyridin-1-yl]-2-hydroxypropoxy]benzamide |
InChI: | InChI=1S/C21H23FN2O3/c22-18-5-1-15(2-6-18)16-9-11-24(12-10-16)13-19(25)14-27-20-7-3-17(4-8-20)21(23)26/h1-9,19,25H,10-14H2,(H2,23,26) |
InChIKey: | HFHFPCVDUCBNLG-UHFFFAOYSA-N |
Canonical Smiles: | C1CN(CC=C1C2=CC=C(C=C2)F)CC(COC3=CC=C(C=C3)C(=O)N)O |
Isomeric Smiles: | C1CN(CC=C1C2=CC=C(C=C2)F)CC(COC3=CC=C(C=C3)C(=O)N)O |
Molecular Weight: | 370.4 |
Molecular Formula: | C21H23FN2O3 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
Ro 8-4304
Molecular Weight: | 370.4 |
Molecular Formula: | C21H23FN2O3 |
Hydrogen Bond Donor Count: | 2 |
Hydrogen Bond Acceptor Count: | 5 |
Rotatable Bond Count: | 7 |
Heavy Atom Count: | 27 |
Complexity: | 512 |
Synonyms
Ro 8-4304
| Ro 8-4304 | Ro 8-4304 |
|---|---|
Ro 8-4304 |
Ro-84304 |
Ro-8-4304 |
Ro84304 |
Lopac0_001043 |
GTPL4300 |
SCHEMBL6021254 |
CHEMBL1257093 |
DTXSID40474701 |
CCG-205120 |
SDCCGSBI-0051013.P002 |
NCGC00015902-02 |
NCGC00015902-03 |
NCGC00015902-05 |
NCGC00162325-01 |
Q27088604 |
4-{3-4-(4-fluorophenyl)-1,2,3,6-tetrahydropyridin-1-yl-2-hydroxypropoxy}benzamide |
Experimental Data
Ro 8-4304
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33 | umol/L | -3 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
Ro 8-4304
Statistics Data
Ro 8-4304
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -3 | 1 | 1 |
Statistics Data Visualization
Ro 8-4304
