Compound Summary
Compound Information
betamethasone
Compound Name: | betamethasone |
Compound CID: | 9782 |
Synonyms: | betamethasone Betadexamethasone 378-44-9 Flubenisolone Betamethazone More... |
Iupac Name: | (8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one |
InChI: | InChI=1S/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15-,16-,17-,19-,20-,21-,22-/m0/s1 |
InChIKey: | UREBDLICKHMUKA-DVTGEIKXSA-N |
Canonical Smiles: | CC1CC2C3CCC4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)CO)O)C)O)F)C |
Isomeric Smiles: | C[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)CO)O)C)O)F)C |
Molecular Weight: | 392.5 |
Molecular Formula: | C22H29FO5 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
betamethasone
Molecular Weight: | 392.5 |
Molecular Formula: | C22H29FO5 |
Hydrogen Bond Donor Count: | 3 |
Hydrogen Bond Acceptor Count: | 6 |
Rotatable Bond Count: | 2 |
Heavy Atom Count: | 28 |
Complexity: | 805 |
Synonyms
betamethasone
| betamethasone | betamethasone |
|---|---|
betamethasone |
Betadexamethasone |
378-44-9 |
Flubenisolone |
Betamethazone |
Rinderon |
Visubeta |
Betacorlan |
Betacortril |
Betamamallet |
Betametasone |
Betapredol |
Betasolon |
Betnelan |
Betsolan |
Celestene |
Methazon |
Becort |
Bedifos |
Cidoten |
beta-Methasone |
Desacort-Beta |
Rinderon A |
beta-Methasone alcohol |
Betametasona |
Betamethasonum |
Bebate |
9alpha-Fluoro-16beta-methylprednisolone |
SCH 4831 |
Dermabet |
9-Fluoro-16beta-methylprednisolone |
NSC-39470 |
SCH-4831 |
UNII-9842X06Q6M |
Betafluorene |
Betamethasone (Celestone) |
MFCD00062969 |
9-Fluoro-11beta,17,21-trihydroxy-16beta-methylpregna-1,4-diene-3,20-dione |
Betamethasone cream |
MLS000859943 |
CHEBI:3077 |
Betamethasone alcohol |
Betametasone DCIT |
NCS-39470 |
9842X06Q6M |
(8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopentaaphenanthren-3-one |
NCGC00164401-01 |
SMR000058601 |
Celestone Syrup and Tablets |
Betametasona INN-Spanish |
Betamethasonum INN-Latin |
DSSTox_CID_2667 |
9a-Fluoro-11b,17a,21-trihydroxy-16b-methylpregna-1,4-diene-3,20-dione |
16beta-Methyl-1,4-pregnadiene-9alpha-fluoro-11beta,17alpha,21-triol-3,20-dione |
DSSTox_RID_76681 |
DSSTox_GSID_22667 |
(8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopentaaphenanthren-3-one |
Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17,21-trihydroxy-16-methyl-, (11.beta.,16.beta.)- |
.beta.-Methasone |
9-Fluoro-16.beta.-methylprednisolone |
(11beta,16beta)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione |
Rinderon (TN) |
.beta.-Methasone alcohol |
9.alpha.-Fluoro-16.beta.-methylprednisolone |
9-alpha-Fluoro-16-beta-methylprednisolone |
HSDB 3015 |
EINECS 206-825-4 |
NSC 39470 |
Prednisolone, 9-fluoro-16beta-methyl- |
BRN 3176546 |
NSC39470 |
Desacort-.beta. |
.beta.-Corlan |
9alpha-Fluoro-11beta,17alpha,21-trihydroxy-16beta-methyl-1,4-pregnadiene-3,20-dione |
NCGC00091019-08 |
CAS-378-44-9 |
Prestwick_703 |
Prednisolone, 9-fluoro-16.beta.-methyl- |
9-Fluoro-11-beta,17,21-trihydroxy-16-beta-methylpregna-1,4-diene-3,20-dione |
Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17,21-trihydroxy-16-methyl-, (11beta,16beta)- |
Betamethasone, topical |
Betamethasone USAN:USP:INN:BAN:JAN |
Corticosterone, 1-dehydro-9-fluoro-17-hydroxy-16beta-methyl- |
Betamethasone, >=98% |
Prestwick0_000362 |
Prestwick1_000362 |
Prestwick2_000362 |
Prestwick3_000362 |
CHEMBL632 |
EC 206-825-4 |
cid_9782 |
SCHEMBL4565 |
16-beta-Methyl-1,4-pregnadiene-9-alpha-fluoro-11-beta,17-alpha,21-triol-3,20-dione |
9-alpha-Fluoro-16-beta-methyl-1,4-pregnadiene-11-beta,17-alpha,21-triol-3,20-dione |
Pregna-1,4-diene-3,20-dione, 9-fluoro-11beta,17,21-trihydroxy-16beta-methyl- |
BIDD:PXR0047 |
BSPBio_000483 |
4-08-00-03501 (Beilstein Handbook Reference) |
MLS001066413 |
MLS001332616 |
MLS002153244 |
SPBio_002404 |
Corticosterone, 1-dehydro-9-fluoro-17-hydroxy-16.beta.-methyl- |
BPBio1_000533 |
GTPL7061 |
DTXSID3022667 |
BDBM73823 |
Betamethasone (JP17/USP/INN) |
BCPP000345 |
HMS1569I05 |
HMS2096I05 |
HMS2233I08 |
HMS3713I05 |
BCP02020 |
ZINC3876136 |
Tox21_112115 |
Tox21_301455 |
s1500 |
AKOS008901360 |
AKOS015894863 |
Tox21_112115_1 |
ACN-043339 |
BCP9000393 |
CCG-220362 |
CS-1897 |
DB00443 |
EBD2157848 |
KS-5302 |
9-Fluoro-11.beta.,17,21-trihydroxy-16.beta.-methylpregna-1,4-diene-3,20-dione |
SMP1_000043 |
Betamethasone Dipropionate EP Impurity A |
NCGC00164401-02 |
NCGC00164401-03 |
NCGC00255195-01 |
HY-13570 |
AB0012192 |
Betamethasone 100 microg/mL in Acetonitrile |
D1961 |
Betamethasone, meets USP testing specifications |
C06848 |
D00244 |
D88866 |
20525-EP2272832A1 |
20525-EP2295409A1 |
20525-EP2298778A1 |
20525-EP2308562A2 |
20525-EP2314585A1 |
20525-EP2314590A1 |
20525-EP2371811A2 |
378M449 |
Betamethasone, VETRANAL(TM), analytical standard |
Q416132 |
SR-01000780582 |
SR-01000780582-2 |
W-106509 |
BRD-K39188321-001-03-9 |
Betamethasone, British Pharmacopoeia (BP) Reference Standard |
Betamethasone, European Pharmacopoeia (EP) Reference Standard |
Betamethasone, pharmaceutical impurity standard, >=95.0% (HPLC) |
Betamethasone, United States Pharmacopeia (USP) Reference Standard |
(11.beta.,16.beta.)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione |
9-.alpha.-Fluoro-11-.beta.,17,21-trihydroxy-16-.beta.-methylpregna-1,4-diene-3,20-dione |
9-alpha-Fluor-11-beta,17-alpha,21-trihydroxy-16-beta-methylpregna-1,4-dien-3,20-dion |
9-fluoro-16beta-methyl-11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione |
9alpha-Fluoro-11beta,17alpha,21-trihydroxy-16beta-methylpregna-1,4-diene-3,20-dione |
9alpha-Fluoro-16beta-methyl-11beta,17alpha,21-trihydroxy-1,4-pregnadiene-3,20-dione |
Betamethasone, Pharmaceutical Secondary Standard; Certified Reference Material |
Pregna-1,4-diene-3,20-dione, 9-fluoro-11.beta.,17,21-trihydroxy-16.beta.-methyl- |
Pregna-1,4-diene-3,20-dione, 9-fluoro-11beta,17,21-trihydroxy-16beta-methyl- (8CI) |
Pregna-1,4-diene-3,20-dione, 9alpha-fluoro-11beta,17alpha,21-trihydroxy-16beta-methyl- |
(1R,2S,10S,11S,13S,14R,15S,17S)-1-fluoro-14,17-dihydroxy-14-(2-hydroxyacetyl)-2,13,15-trimethyltetracyclo8.7.0.0^{2,7}.0^{11,15}heptadeca-3,6-dien-5-one |
16-.beta.-Methyl-1,4-pregnadiene-9-.alpha.-fluoro-11-.beta.,17-.alpha.,21-triol-3,20-dione |
9-.alpha.-Fluoro-11-.beta.,17-.alpha.,21-trihydroxy-16-.beta.-methylpregna-1,4-diene-3,20-dione |
9-.alpha.-Fluoro-16-.beta.-methyl-1,4-pregnadiene-11-.beta.,17-.alpha.,21-triol-3,20-dione |
9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione, (11.beta.,16.beta.) # |
Betamethasone; 9-Fluoro-11?,17,21-trihydroxy-16?-methylpregna-1,4-diene-3,20-dione; (11?,16?)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione; 9?-Fluoro-16?-methylprednisolone |
Experimental Data
betamethasone
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33 | umol/L | 16 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
betamethasone
Statistics Data
betamethasone
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 16 | 1 | 1 |
Statistics Data Visualization
betamethasone
