Compound Summary
Compound Information
thiothixene
Compound Name: | thiothixene |
Compound CID: | 941651 |
Synonyms: | thiothixene cis-Thiothixene Tiotixene (Z)-Thiothixene Navane More... |
Iupac Name: | (9Z)-N,N-dimethyl-9-[3-(4-methylpiperazin-1-yl)propylidene]thioxanthene-2-sulfonamide |
InChI: | InChI=1S/C23H29N3O2S2/c1-24(2)30(27,28)18-10-11-23-21(17-18)19(20-7-4-5-9-22(20)29-23)8-6-12-26-15-13-25(3)14-16-26/h4-5,7-11,17H,6,12-16H2,1-3H3/b19-8- |
InChIKey: | GFBKORZTTCHDGY-UWVJOHFNSA-N |
Canonical Smiles: | CN1CCN(CC1)CCC=C2C3=CC=CC=C3SC4=C2C=C(C=C4)S(=O)(=O)N(C)C |
Isomeric Smiles: | CN1CCN(CC1)CC/C=C\2/C3=CC=CC=C3SC4=C2C=C(C=C4)S(=O)(=O)N(C)C |
Molecular Weight: | 443.6 |
Molecular Formula: | C23H29N3O2S2 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
thiothixene
Molecular Weight: | 443.6 |
Molecular Formula: | C23H29N3O2S2 |
Hydrogen Bond Donor Count: | 0 |
Hydrogen Bond Acceptor Count: | 6 |
Rotatable Bond Count: | 5 |
Heavy Atom Count: | 30 |
Complexity: | 711 |
Synonyms
thiothixene
| thiothixene | thiothixene |
|---|---|
thiothixene |
cis-Thiothixene |
Tiotixene |
(Z)-Thiothixene |
Navane |
3313-26-6 |
Thiothixine |
Tiotixenum INN-Latin |
Tiotixeno INN-Spanish |
Navaron |
Orbinamon |
Navan |
Thiothixene hydrochloride |
(9Z)-N,N-dimethyl-9-3-(4-methylpiperazin-1-yl)propylidenethioxanthene-2-sulfonamide |
NSC-108165 |
UNII-7318FJ13YJ |
MLS000028463 |
5591-45-7 |
SMR000058396 |
CP-12,252-1 |
CP 12252-1 |
7318FJ13YJ |
Thiothixene (Z) |
CP-12,252-1 base |
Tiotixeno |
Tiotixenum |
9H-Thioxanthene-2-sulfonamide, N,N-dimethyl-9-3-(4-methyl-1-piperazinyl)propylidene- |
P-4657 B |
P-4657-B |
Tiotixene (JAN) |
Thiothixene (USP) |
Navane (TN) |
Thiothixene USAN |
2-(Dimethylsulfamoyl)-(9-(4-methyl-1-piperazinyl)propylidene)thioxanthene |
N,N-Dimethyl-9-3-(4-methyl-1-piperazinyl)propylidenethioxanthene-2-sulfonamide |
NSC108165 |
Thioxanthene-2-sulfonamide, N,N-dimethyl-9-(3-(4-methyl-1-piperazinyl)propylidene)- |
Tiotixene INN |
cis-N,N-Dimethyl-9-(3-(4-methyl-1-piperazinyl)propylidene)thioxanthene-2-sulfonamide |
P-4657B |
Opera_ID_626 |
CHEMBL1201 |
BIDD:PXR0153 |
Lopac0_001144 |
SCHEMBL34305 |
GTPL212 |
MLS006010662 |
CHEBI:9571 |
cid_941651 |
DTXSID2091542 |
BDBM78576 |
AOB5787 |
N,N-Dimethyl-9-(3-(4-methyl-1-piperazinyl)propylidene)thiaxanthene-2-sulfonamide |
HMS2230F08 |
HMS3887A07 |
MFCD00079574 |
PDSP1_000038 |
PDSP1_000625 |
PDSP1_000626 |
PDSP2_000038 |
PDSP2_000622 |
ZINC30690433 |
{2-(Dimethylsulfamoyl)-9-(4-methyl-1-piperazinyl)propylidenethiox} anthene |
AKOS015850761 |
CCG-205218 |
CS-7959 |
DB01623 |
Thioxanthene-2-sulfonamide, N,N-dimethyl-9-(3-(4-methyl-1-piperazinyl)propylidene)-, (Z)- |
NCGC00162353-01 |
AS-16925 |
HY-108324 |
Thiothixene, meets USP testing specifications |
D00374 |
Q2608288 |
UNII-LF886533UR component GFBKORZTTCHDGY-UWVJOHFNSA-N |
Thiothixene, United States Pharmacopeia (USP) Reference Standard |
(9Z)-N,N-dimethyl-9-3-(4-methylpiperazin-1-yl)propylidene-9H-thioxanthene-2-sulfonamide |
(Z)-N,N-Dimethyl-9-(3-(4-methylpiperazin-1-yl)propylidene)-9H-thioxanthene-2-sulfonamide |
N,N-Dimethyl-9-3-(4-methyl-1-piperazinyl)propylidene-9H-thioxanthene-2-sulfonamide # |
9H-Thioxanthene-2-sulfonamide, N, {N-dimethyl-9-3-(4-methyl-1-piperazinyl)propylidene-,} (Z)- |
Experimental Data
thiothixene
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33 | umol/L | 5 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
thiothixene
Statistics Data
thiothixene
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 5 | 1 | 1 |
Statistics Data Visualization
thiothixene
