Compound Summary
Compound Information
Mitraphylline
Compound Name: | Mitraphylline |
Compound CID: | 94160 |
Synonyms: | Mitraphylline 509-80-8 Mitraphilline UNII-1H9SRL2456 Methyl 19alpha-methyl-2-oxoformosanan-16-carboxylate More... |
Iupac Name: | methyl (1S,4aS,5aS,6R,10aR)-1-methyl-2'-oxospiro[1,4a,5,5a,7,8,10,10a-octahydropyrano[3,4-f]indolizine-6,3'-1H-indole]-4-carboxylate |
InChI: | InChI=1S/C21H24N2O4/c1-12-14-10-23-8-7-21(16-5-3-4-6-17(16)22-20(21)25)18(23)9-13(14)15(11-27-12)19(24)26-2/h3-6,11-14,18H,7-10H2,1-2H3,(H,22,25)/t12-,13-,14+,18-,21+/m0/s1 |
InChIKey: | JMIAZDVHNCCPDM-DAFCLMLCSA-N |
Canonical Smiles: | CC1C2CN3CCC4(C3CC2C(=CO1)C(=O)OC)C5=CC=CC=C5NC4=O |
Isomeric Smiles: | C[C@H]1[C@H]2CN3CC[C@]4([C@@H]3C[C@@H]2C(=CO1)C(=O)OC)C5=CC=CC=C5NC4=O |
Molecular Weight: | 368.4 |
Molecular Formula: | C21H24N2O4 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
Mitraphylline
Molecular Weight: | 368.4 |
Molecular Formula: | C21H24N2O4 |
Hydrogen Bond Donor Count: | 1 |
Hydrogen Bond Acceptor Count: | 5 |
Rotatable Bond Count: | 2 |
Heavy Atom Count: | 27 |
Complexity: | 692 |
Synonyms
Mitraphylline
| Mitraphylline | Mitraphylline |
|---|---|
Mitraphylline |
509-80-8 |
Mitraphilline |
UNII-1H9SRL2456 |
Methyl 19alpha-methyl-2-oxoformosanan-16-carboxylate |
CHEBI:6957 |
1H9SRL2456 |
Ajmalicine oxindole B |
MLS000728610 |
Rubradinine |
EINECS 208-106-0 |
SEC-BUTYLMETHYLSULFIDE |
CHEMBL2135897 |
DTXSID50198926 |
HMS2267P09 |
HY-N6946 |
ZINC1607834 |
CCG-36401 |
NSC717700 |
NSC-717700 |
methyl (1S,4aS,5aS,6R,10aR)-1-methyl-2-oxospiro1,4a,5,5a,7,8,10,10a-octahydropyrano3,4-findolizine-6,3-1H-indole-4-carboxylate |
SMR000470795 |
CS-0081397 |
C09227 |
Q10859059 |
Methyl (19alpha)-19-methyl-2-oxoformosanan-16-carboxylate |
(1S,3R,4aS,5aS,10aR)-methyl 1-methyl-2-oxo-1,4a,5,5a,7,8,10,10a-octahydrospiroindoline-3,6-pyrano3,4-findolizine-4-carboxylate" |
Experimental Data
Mitraphylline
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 2 | ug/mL | Unclear | N2 | 33683565 | ||||||||
| Caenorhabditis elegans | 1 | ug/mL | Unclear | N2 | 33683565 | ||||||||
| Caenorhabditis elegans | 10 | ug/mL | Unclear | N2 | 33683565 |
Experimental Data Visualization
Mitraphylline
Statistics Data
Mitraphylline
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 1 | 3 |
Statistics Data Visualization
Mitraphylline
