Compound Summary
Compound Information
PHENFORMIN
Compound Name: | PHENFORMIN |
Compound CID: | 8249 |
Synonyms: | PHENFORMIN 114-86-3 N-Phenethylbiguanide Fenformin Phenformine More... |
Iupac Name: | 1-(diaminomethylidene)-2-(2-phenylethyl)guanidine |
InChI: | InChI=1S/C10H15N5/c11-9(12)15-10(13)14-7-6-8-4-2-1-3-5-8/h1-5H,6-7H2,(H6,11,12,13,14,15) |
InChIKey: | ICFJFFQQTFMIBG-UHFFFAOYSA-N |
Canonical Smiles: | C1=CC=C(C=C1)CCN=C(N)N=C(N)N |
Isomeric Smiles: | C1=CC=C(C=C1)CCN=C(N)N=C(N)N |
Molecular Weight: | 205.26 |
Molecular Formula: | C10H15N5 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
PHENFORMIN
Molecular Weight: | 205.26 |
Molecular Formula: | C10H15N5 |
Hydrogen Bond Donor Count: | 3 |
Hydrogen Bond Acceptor Count: | 1 |
Rotatable Bond Count: | 4 |
Heavy Atom Count: | 15 |
Complexity: | 236 |
Synonyms
PHENFORMIN
| PHENFORMIN | PHENFORMIN |
|---|---|
PHENFORMIN |
114-86-3 |
N-Phenethylbiguanide |
Fenformin |
Phenformine |
Phenethyldiguanide |
Fenformina |
Pedg |
Phenylethylbiguanide |
Cronoformin |
Fenfoduron |
Fenormin |
Glukopostin |
Phenformix |
Debeone |
Diabis |
Dibiraf |
Dibotin |
Glyphen |
Retardo |
Db-retard |
beta-PEBG |
DB Comb |
1-Phenethylbiguanide |
Imidodicarbonimidic diamide, N-(2-phenylethyl)- |
beta-Phenethylbiguanide |
Phenforminum |
Normoglucina |
Fenformina INN-Spanish |
Phenformine INN-French |
Phenforminum INN-Latin |
N-(2-Phenylethyl)imidodicarbonimidic diamide |
Biguanide, 1-phenethyl- |
beta-Phenethybiguanide |
W 32 |
NCI-C01741 |
UNII-DD5K7529CE |
CHEBI:8064 |
Phenoformine hydrochloride |
Feguanide |
Lentobetic |
Azucaps |
Debinyl |
Insoral |
Dibein |
D Bretard |
N-Phenethylbiguanide hydrochloride |
CHEMBL170988 |
DD5K7529CE |
1-(diaminomethylidene)-2-(2-phenylethyl)guanidine |
1-carbamimidamido-N-(2-phenylethyl)methanimidamide |
2-(N-phenethylcarbamimidoyl)guanidine |
MFCD00242966 |
114-86-3 (FREE BASE) |
Phenformine HCl |
Phenformin INN:BAN |
Phenformin (BAN) |
CCRIS 500 |
N-beta-Phenethylformamidinylliminourea |
HSDB 3154 |
N-beta-Fenetilformamidiniliminourea |
NCGC00016543-01 |
CAS-834-28-6 |
N-beta-Fenetilformamidiniliminourea Italian |
EINECS 204-057-4 |
amino{imino(2-phenylethyl)aminomethyl}carboxamidine |
BRN 1977317 |
Dipar (Salt/Mix) |
.beta.-PEBG |
Meltrol (Salt/Mix) |
.beta.-Phenethylbiguanide |
Prestwick0_000179 |
Prestwick1_000179 |
Prestwick2_000179 |
Prestwick3_000179 |
SCHEMBL8424 |
BSPBio_000077 |
KBioGR_002392 |
KBioSS_002397 |
4-12-00-02472 (Beilstein Handbook Reference) |
MLS006011899 |
SPBio_001998 |
BPBio1_000085 |
DTXSID1023449 |
SCHEMBL10325620 |
SCHEMBL17300524 |
KBio2_002392 |
KBio2_004960 |
KBio2_007528 |
KBio3_002871 |
cMAP_000038 |
HMS3604G03 |
ALBB-026048 |
ZINC5851063 |
AC3005 |
BBL010845 |
BDBM50237608 |
BDBM50240908 |
NSC756501 |
SBB072819 |
STK635703 |
1-carbamimidoyl-3-phenethyl-guanidine |
AKOS005567415 |
N-.beta.-Fenetilformamidiniliminourea |
DB00914 |
MCULE-1254555434 |
NSC-756501 |
NCGC00016543-02 |
NCGC00016543-03 |
NCGC00016543-04 |
NCGC00016543-05 |
NCGC00016543-08 |
CS-11859 |
M819 |
N-.beta.-Phenethylformamidinylliminourea |
SMR004703510 |
SY031759 |
N-(2-Phenylethyl)dicarbonimidic diamide # |
SBI-0206879.P001 |
ST45029292 |
C07673 |
D08351 |
Q753100 |
N-{amino(2-phenylethyl)iminomethyl}guanidine |
BRD-K11399644-003-03-0 |
N-(2-phenylethyl)imidodicarbonimidic diamide(Phenformin) |
Imidodicarbonimidic diamide, N-(2-phenylethyl)-, hydrochloride |
N-(E)-amino(imino)methyl-N-(2-phenylethyl)guanidine |
N-amino(imino)methyl-N-phenethyliminomethanediamine(Phenformin) |
8CV |
Experimental Data
PHENFORMIN
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Mus musculus | 2 | mg | 450 | 555 | 23.33 | Unclear | 7390164 | ||||||
| Mus musculus | 2 | mg | 450 | 545 | 21.1 | 643 | 810 | 26 | S | C3H/Sn | FEMALES | 21084729 | Active |
| Rattus norvegicus | 652 | 652 | 0 | 919 | 1009 | 9.8 | NS | LIO | FEMALES | 21084729 | Inactive | ||
| Mus musculus | 2 | mg | 450 | 545 | 21.1 | 643 | 810 | 26 | S | C3H/Sn | FEMALES | 14618027 | Active |
| Rattus norvegicus | 5 | mg | 652 | 652 | 0 | 919 | 1009 | 9.8 | NS | LIO | FEMALES | 14618027 | Inactive |
| Caenorhabditis elegans | 1.5 | mM | 5 | S | N2 | 23540700 | Active | ||||||
| Caenorhabditis elegans | 3 | mM | 21 | S | N2 | 23540700 | Active | ||||||
| Caenorhabditis elegans | 4.5 | mM | 26 | S | N2 | 23540700 | Active |
Experimental Data Visualization
PHENFORMIN
Statistics Data
PHENFORMIN
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 26 | 1 | 3 | |
| Mus musculus | 23.33 | 26 | 3 | 3 |
| Rattus norvegicus | 0 | 9.8 | 2 | 2 |
Statistics Data Visualization
PHENFORMIN
