Compound Summary
Compound Information
Bilobalide
Compound Name: | Bilobalide |
Compound CID: | 73581 |
Synonyms: | Bilobalide 33570-04-6 Bilobalid (-)-Bilobalide Bilobalide A More... |
Iupac Name: | (1S,4R,7R,8S,9R,11S)-9-tert-butyl-7,9-dihydroxy-3,5,12-trioxatetracyclo[6.6.0.01,11.04,8]tetradecane-2,6,13-trione |
InChI: | InChI=1S/C15H18O8/c1-12(2,3)14(20)4-6-13(5-7(16)21-6)10(19)23-11-15(13,14)8(17)9(18)22-11/h6,8,11,17,20H,4-5H2,1-3H3/t6-,8-,11-,13-,14+,15+/m0/s1 |
InChIKey: | MOLPUWBMSBJXER-YDGSQGCISA-N |
Canonical Smiles: | CC(C)(C)C1(CC2C3(C14C(C(=O)OC4OC3=O)O)CC(=O)O2)O |
Isomeric Smiles: | CC(C)(C)[C@@]1(C[C@H]2[C@@]3([C@]14[C@H](C(=O)O[C@H]4OC3=O)O)CC(=O)O2)O |
Molecular Weight: | 326.3 |
Molecular Formula: | C15H18O8 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
Bilobalide
Molecular Weight: | 326.3 |
Molecular Formula: | C15H18O8 |
Hydrogen Bond Donor Count: | 2 |
Hydrogen Bond Acceptor Count: | 8 |
Rotatable Bond Count: | 1 |
Heavy Atom Count: | 23 |
Complexity: | 650 |
Synonyms
Bilobalide
| Bilobalide | Bilobalide |
|---|---|
Bilobalide |
33570-04-6 |
Bilobalid |
(-)-Bilobalide |
Bilobalide A |
UNII-M81D2O8H7U |
CHEBI:3103 |
M81D2O8H7U |
(3aS,8R,8aS,9R,10aS)-9-tert-butyl-8,9-dihydroxydihydro-9H-furo2,3-bfuro3,2:2,3cyclopenta1,2-cfuran-2,4,7(3H,8H)-trione |
tert-butyl(dihydroxy)?trione |
Bilobalide; |
Bilobalide A; |
(?)-Bilobalide |
MLS000563448 |
SCHEMBL285824 |
GTPL2366 |
CHEMBL1318117 |
HMS2205O12 |
4H,5aH,9H-Furo2,3-bfuro3,2:2,3cyclopenta1,2-cfuran-2,4,7(3H,8H)-trione, 9-(1,1-dimethylethyl)-10,10a-dihydro-8,9-dihydroxy-, (3aS,5aR,8R,8aS,9R,10aS)- |
BCP28255 |
C15H18O8 |
HY-N0076 |
ZINC8679998 |
MFCD00132880 |
MFCD00238547 |
AKOS024282583 |
CCG-208160 |
CS-1517 |
NCGC00142501-01 |
NCGC00142501-02 |
4H,5aH,9H-Furo(2,3-b)furo(3,2:2,3)cyclopenta(1,2-c)furan-2,4,7(3H,8H)-trione, 9-(1,1-dimethylethyl)-10,10a-dihydro-8,9-dihydroxy-, (5aR-(3aS*,5aalpha,8beta,8aS*,9alpha,10aalpha))- |
AS-17551 |
SMR000232342 |
ST057155 |
N1894 |
V0679 |
570B046 |
Q418459 |
SR-01000712074 |
Q-100409 |
SR-01000712074-4 |
(-)-Bilobalide from Ginkgo biloba leaves, >=93% (HPLC) |
(1S,4R,7R,8S,9R,11S)-9-tert-butyl-7,9-dihydroxy-3,5,12-trioxatetracyclo6.6.0.0^{1,11}.0^{4,8}tetradecane-2,6,13-trione |
(1S,8S,12S,5R,14R)-14-(tert-butyl)-2,14-dihydroxy-4,6,11-trioxatetracyclo6.6. 0.0<1,5>.0<8,12>tetradecane-3,7,10-trione |
4H,5aH,9H-Furo2,3-bfuro3,2:2,3cyclopenta1,2-cfuran-2,4,7(3H,8H)-trione, 9-(1,1-dimethylethyl)-10,10a-dihydro-8,9-dihydroxy-,(3aS,5aR,8R,8aS,9R,10aS)-" |
Experimental Data
Bilobalide
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 50 | ug/mL | -5.56 | Unclear | N2 | 33683565 |
Experimental Data Visualization
Bilobalide
Statistics Data
Bilobalide
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -5.56 | 1 | 1 |
Statistics Data Visualization
Bilobalide
