Compound Summary
Compound Information
Amperozide hydrochloride
Compound Name: | Amperozide hydrochloride |
Compound CID: | 73334 |
Synonyms: | Amperozide hydrochloride Amperozide HCl Hogpax 86725-37-3 75529-73-6 More... |
Iupac Name: | 4-[4,4-bis(4-fluorophenyl)butyl]-N-ethylpiperazine-1-carboxamide;hydrochloride |
InChI: | InChI=1S/C23H29F2N3O.ClH/c1-2-26-23(29)28-16-14-27(15-17-28)13-3-4-22(18-5-9-20(24)10-6-18)19-7-11-21(25)12-8-19;/h5-12,22H,2-4,13-17H2,1H3,(H,26,29);1H |
InChIKey: | OEQHKNWFXHBJIT-UHFFFAOYSA-N |
Canonical Smiles: | CCNC(=O)N1CCN(CC1)CCCC(C2=CC=C(C=C2)F)C3=CC=C(C=C3)F.Cl |
Isomeric Smiles: | CCNC(=O)N1CCN(CC1)CCCC(C2=CC=C(C=C2)F)C3=CC=C(C=C3)F.Cl |
Molecular Weight: | 438 |
Molecular Formula: | C23H30ClF2N3O |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
Amperozide hydrochloride
Molecular Weight: | 438 |
Molecular Formula: | C23H30ClF2N3O |
Hydrogen Bond Donor Count: | 2 |
Hydrogen Bond Acceptor Count: | 4 |
Rotatable Bond Count: | 7 |
Heavy Atom Count: | 30 |
Complexity: | 461 |
Synonyms
Amperozide hydrochloride
| Amperozide hydrochloride | Amperozide hydrochloride |
|---|---|
Amperozide hydrochloride |
Amperozide HCl |
Hogpax |
86725-37-3 |
75529-73-6 |
UNII-8V2171U69N |
8V2171U69N |
NCGC00093556-01 |
4-4,4-bis(4-fluorophenyl)butyl-N-ethylpiperazine-1-carboxamide;hydrochloride |
DSSTox_CID_25750 |
DSSTox_RID_81094 |
DSSTox_GSID_45750 |
4-(4,4-Bis(p-fluorophenyl)butyl)-N-ethyl-1-piperazinecarboxamide hydrochloride |
CAS-75529-73-6 |
FG 5606 |
FG-5606 |
Amperozide hydrochloride MI |
Amperozide hydrochloride WHO-DD |
amperozide monohydrochloride |
MLS002153519 |
SCHEMBL1321270 |
CHEMBL1257106 |
DTXSID5045750 |
AOB5283 |
CHEBI:180485 |
DTXSID501019079 |
Tox21_111208 |
Tox21_500040 |
AKOS024457273 |
Tox21_111208_1 |
LP00040 |
4-4,4-bis(4-Fluorophenyl)butyl-N-ethyl-1-piperazinecarboxamide hydrochloride |
4-4,4-bis(4-fluorophenyl)butyl-N-ethylpiperazine-1-carboxamide hydrochloride |
NCGC00015081-04 |
NCGC00260725-01 |
AS-16836 |
SMR001230851 |
EU-0100040 |
A 6976 |
SR-01000076207 |
SR-01000076207-1 |
Q27271058 |
1-4,4-bis(4-fluorophenyl)butyl-4-(ethylcarbamoyl)piperazin-1-ium chloride |
1-Piperazinecarboxamide, 4-(4,4-bis(4-fluorophenyl)butyl)-N-ethyl-, hydrochloride (1:?) |
Experimental Data
Amperozide hydrochloride
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33 | umol/L | 38 | S | N2 | 33683565 | Active | ||||||
| Caenorhabditis elegans | 33 | umol/L | 25 | NS | N2 | 24134630 | Inactive | ||||||
| Caenorhabditis elegans | 13 | umol/L | 38 | S | N2 | 24134630 | Active |
Experimental Data Visualization
Amperozide hydrochloride
Statistics Data
Amperozide hydrochloride
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 38 | 2 | 3 |
Statistics Data Visualization
Amperozide hydrochloride
