Compound Summary
Compound Information
H-7 dihydrochloride
Compound Name: | H-7 dihydrochloride |
Compound CID: | 73332 |
Synonyms: | H-7 dihydrochloride 108930-17-2 1-(5-Isoquinolinylsulfonyl)-2-methylpiperazine dihydrochloride H7 dihydrochloride H-7, Dihydrochloride More... |
Iupac Name: | 5-(2-methylpiperazin-1-yl)sulfonylisoquinoline;dihydrochloride |
InChI: | InChI=1S/C14H17N3O2S.2ClH/c1-11-9-16-7-8-17(11)20(18,19)14-4-2-3-12-10-15-6-5-13(12)14;;/h2-6,10-11,16H,7-9H2,1H3;2*1H |
InChIKey: | OARGPFMFRLLKPF-UHFFFAOYSA-N |
Canonical Smiles: | CC1CNCCN1S(=O)(=O)C2=CC=CC3=C2C=CN=C3.Cl.Cl |
Isomeric Smiles: | CC1CNCCN1S(=O)(=O)C2=CC=CC3=C2C=CN=C3.Cl.Cl |
Molecular Weight: | 364.3 |
Molecular Formula: | C14H19Cl2N3O2S |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
H-7 dihydrochloride
Molecular Weight: | 364.3 |
Molecular Formula: | C14H19Cl2N3O2S |
Hydrogen Bond Donor Count: | 3 |
Hydrogen Bond Acceptor Count: | 5 |
Rotatable Bond Count: | 2 |
Heavy Atom Count: | 22 |
Complexity: | 434 |
Synonyms
H-7 dihydrochloride
| H-7 dihydrochloride | H-7 dihydrochloride |
|---|---|
H-7 dihydrochloride |
108930-17-2 |
1-(5-Isoquinolinylsulfonyl)-2-methylpiperazine dihydrochloride |
H7 dihydrochloride |
H-7, Dihydrochloride |
1-(5-Isoquinolinesulfonyl)-2-methylpiperazine dihydrochloride |
CHEBI:82739 |
MFCD00036961 |
5-((2-methylpiperazin-1-yl)sulfonyl)isoquinoline dihydrochloride |
SR-01000000121 |
1-(5-isoquinolylsulfonyl)-2-methylpiperazine, chloride, chloride |
5-(2-methylpiperazin-1-yl)sulfonylisoquinoline dihydrochloride |
1-(5-Isoquinolinesulfonyl)-2-methyl-piperazine dihydrochloride |
H-7DIHYDROCHLORIDE |
BMK1-B4 |
1-(5-Isoquinolinesulfonyl)-2-methylpiperazine, 2HCl |
CHEMBL540848 |
SCHEMBL1064436 |
DTXSID10910929 |
5-(2-methylpiperazin-1-ylsulfonyl)isoquinoline dihydrochloride |
Isoquinoline-5-sulfonic 2-methyl-1-piperazide dihydrochloride |
to_000064 |
Tox21_500682 |
Piperazine, 1-(5-isoquinolinylsulfonyl)-2-methyl-, dihydrochloride |
SBB027327 |
AKOS024458555 |
CCG-221986 |
LP00682 |
H-7 dihydrochloride, >=98% (HPLC) |
NCGC00094040-01 |
NCGC00261367-01 |
EU-0100598 |
EU-0100682 |
H-121 |
ST50826284 |
I 7016 |
H-7, Dihydrochloride - CAS 108930-17-2 |
J-002210 |
SR-01000000121-2 |
SR-01000000121-3 |
SR-01000000121-6 |
Q27156263 |
1-(5-isoquinolinesulfonyl)-2-methylpiperazine hydrochloride |
5-(2-methylpiperazin-1-yl)sulfonylisoquinoline;dihydrochloride |
(-)-1-(5-Isoquinolinesulfonyl)-2-methylpiperazine, Di-HCl salt |
5-(2-methylpiperazin-4-ium-1-yl)sulfonylisoquinolinium dichloride |
(+/-)-1-(5-Isoquinolinesulphonyl)-2-methylpiperazine dihydrochloride |
Experimental Data
H-7 dihydrochloride
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33 | umol/L | 2 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
H-7 dihydrochloride
Statistics Data
H-7 dihydrochloride
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 2 | 1 | 1 |
Statistics Data Visualization
H-7 dihydrochloride
