Compound Summary
Compound Information
5-(N-Methyl-N-isobutyl)amiloride
Compound Name: | 5-(N-Methyl-N-isobutyl)amiloride |
Compound CID: | 73314 |
Synonyms: | 5-(N-Methyl-N-isobutyl)amiloride 96861-65-3 Methylisobutylamiloride 3-amino-6-chloro-N-(diaminomethylidene)-5-methyl(2-methylpropyl)aminopyrazine-2-carboxamide 5-Nmnia More... |
Iupac Name: | 3-amino-6-chloro-N-(diaminomethylidene)-5-[methyl(2-methylpropyl)amino]pyrazine-2-carboxamide |
InChI: | InChI=1S/C11H18ClN7O/c1-5(2)4-19(3)9-7(12)16-6(8(13)17-9)10(20)18-11(14)15/h5H,4H2,1-3H3,(H2,13,17)(H4,14,15,18,20) |
InChIKey: | RVIUMPLAOXSSGN-UHFFFAOYSA-N |
Canonical Smiles: | CC(C)CN(C)C1=NC(=C(N=C1Cl)C(=O)N=C(N)N)N |
Isomeric Smiles: | CC(C)CN(C)C1=NC(=C(N=C1Cl)C(=O)N=C(N)N)N |
Molecular Weight: | 299.76 |
Molecular Formula: | C11H18ClN7O |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
5-(N-Methyl-N-isobutyl)amiloride
Molecular Weight: | 299.76 |
Molecular Formula: | C11H18ClN7O |
Hydrogen Bond Donor Count: | 3 |
Hydrogen Bond Acceptor Count: | 5 |
Rotatable Bond Count: | 4 |
Heavy Atom Count: | 20 |
Complexity: | 372 |
Synonyms
5-(N-Methyl-N-isobutyl)amiloride
| 5-(N-Methyl-N-isobutyl)amiloride | 5-(N-Methyl-N-isobutyl)amiloride |
|---|---|
5-(N-Methyl-N-isobutyl)amiloride |
96861-65-3 |
Methylisobutylamiloride |
3-amino-6-chloro-N-(diaminomethylidene)-5-methyl(2-methylpropyl)aminopyrazine-2-carboxamide |
5-Nmnia |
Lopac-A-5585 |
Lopac0_000048 |
MLS002153509 |
SCHEMBL2432777 |
SCHEMBL9852472 |
CHEMBL1256180 |
DTXSID50242594 |
ZINC4467875 |
5-(N-Methyl-N-isobutyl)??amiloride |
CCG-204144 |
NCGC00015068-01 |
NCGC00015068-02 |
NCGC00015068-03 |
NCGC00015068-04 |
NCGC00093562-01 |
NCGC00093562-02 |
SMR001230841 |
EU-0100048 |
A 5585 |
SR-01000075678 |
SR-01000075678-1 |
5-(N-Methyl-N-isobutyl)??amiloride, >=98% (TLC), powder |
3-Amino-5-(N-methyl-N-isobutylamino)-N-(aminoiminomethyl)-6-chloropyrazinecarboxamide |
3-amino-N-carbamimidoyl-6-chloro-5-isobutyl(methyl)aminopyrazine-2-carboxamide |
Pyrazinecarboxamide, 3-amino-N-(aminoiminomethyl)-6-chloro-5-(methyl(2-methylpropyl)amino)- |
Experimental Data
5-(N-Methyl-N-isobutyl)amiloride
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33 | umol/L | -4 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
5-(N-Methyl-N-isobutyl)amiloride
Statistics Data
5-(N-Methyl-N-isobutyl)amiloride
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -4 | 1 | 1 |
Statistics Data Visualization
5-(N-Methyl-N-isobutyl)amiloride
