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Compound Summary

Compound Information

Nobiletin

Compound Name:	Nobiletin
Compound CID:	72344
Synonyms:	Nobiletin 478-01-3 Hexamethoxyflavone 3,4,5,6,7,8-Hexamethoxyflavone" 5,6,7,8,3,4-Hexamethoxyflavone More...
Iupac Name:	2-(3,4-dimethoxyphenyl)-5,6,7,8-tetramethoxychromen-4-one
InChI:	InChI=1S/C21H22O8/c1-23-13-8-7-11(9-15(13)24-2)14-10-12(22)16-17(25-3)19(26-4)21(28-6)20(27-5)18(16)29-14/h7-10H,1-6H3
InChIKey:	MRIAQLRQZPPODS-UHFFFAOYSA-N
Canonical Smiles:	COC1=C(C=C(C=C1)C2=CC(=O)C3=C(O2)C(=C(C(=C3OC)OC)OC)OC)OC
Isomeric Smiles:	COC1=C(C=C(C=C1)C2=CC(=O)C3=C(O2)C(=C(C(=C3OC)OC)OC)OC)OC
Molecular Weight:	402.4
Molecular Formula:	C21H22O8

Compound Structure

2D Structure:

3D Structure:

Computed Properties

Nobiletin

Molecular Weight:	402.4
Molecular Formula:	C21H22O8
Hydrogen Bond Donor Count:	0
Hydrogen Bond Acceptor Count:	8
Rotatable Bond Count:	7
Heavy Atom Count:	29
Complexity:	593

Synonyms

Nobiletin

Nobiletin	Nobiletin
Nobiletin	478-01-3
Hexamethoxyflavone	3,4,5,6,7,8-Hexamethoxyflavone"
5,6,7,8,3,4-Hexamethoxyflavone	UNII-D65ILJ7WLY
2-(3,4-dimethoxyphenyl)-5,6,7,8-tetramethoxychromen-4-one	2-(3,4-Dimethoxyphenyl)-5,6,7,8-tetramethoxy-4H-1-benzopyran-4-one
NSC-76751	D65ILJ7WLY
2-(3,4-dimethoxyphenyl)-5,6,7,8-tetramethoxy-4H-chromen-4-one	CHEMBL76447
Nobiletin (Hexamethoxyflavone)	CHEBI:7602
NSC76751	MFCD03273560
Flavone, 5,6,7,8,3,4-hexamethoxy	4H-1-Benzopyran-4-one, 2-(3,4-dimethoxyphenyl)-5,6,7,8-tetramethoxy-
SMR000156231	CCRIS 9012
NSC 76751	CPD000156231
Nobiletin, >=97%	Spectrum2_001697
Spectrum3_000921	Spectrum4_001020
KBioGR_001519	MLS000574877
MLS000759462	MLS000877030
MLS001424129	Nobiletin, analytical standard
SCHEMBL244029	SPECTRUM1505268
SPBio_001654	MEGxp0_000930
ACon1_000921	KBio3_001922
DTXSID30197275	2-(3,4-dimethoxyphenyl)-5,6,7,8-tetramethoxy-chromen-4-one
HMS2051D09	HMS2234A09
HMS3373C14	HMS3393D09
HMS3651G20	HY-N0155
ZINC1531669	345,6,7,8-Hexamethoxyflavone
3,4,5,6,7,8-Hexamethoxyflavone	BDBM50338976
CCG-38781	CN0043
LMPK12111468	NSC618903
STL565829	AKOS015965334
NOBILETIN, 20% (Technical Grade)	AC-1023
CS-5518	MCULE-1015144950
NC00186	NSC-618903
SDCCGMLS-0066776.P001	NCGC00095703-01
NCGC00095703-02	NCGC00095703-06
NCGC00169228-01	5,6,7,8,3,4-hexamethoxyflavone
AS-17452	NCI60_041691
DB-050181	FT-0686667
N0871	N1311
S2333	SW197566-2
V0181	A827343
SR-01000712262	Q-100511
Q2402963	SR-01000712262-5
BRD-K06753942-001-02-0	2-(3,4-Dimethoxy-phenyl)-5,6,7,8-tetramethoxy-chromen-4-one
4,5,6,7,8,9,10,11,12,13-decahydrocyclododecadoxazole	4H-1-Benzopyran-4-one,4-dimethoxyphenyl)-5,6,7,8-tetramethoxy-
2-(3,4-Dimethoxyphenyl)-5,6,7,8-tetramethoxy-4H-1-benzopyran-4-one, 9CI	3 inverted exclamation mark ,4 inverted exclamation mark ,5,6,7,8-HEXAMETHOXYFLAVONE
4H-1-Benzopyran-4-one, 2-(3,4-dimethoxyphenyl)-5,6,7,8-tetramethoxy- (9CI)

Experimental Data

Nobiletin

Species	Dosage	Unit	CG Lifespan(AVG/MED days)	TG Lifespan(AVG/MED days)	Lifespan Change(AVG/MED%)	CG Lifespan(MAX days)	TG Lifespan(MAX days)	Lifespan Change(MAX%)	Significant	Strain	Gender	PubMed	Active Label
Caenorhabditis elegans	12.5	umol/L							Unclear	N2		33683565
Caenorhabditis elegans	3.13	umol/L							Unclear	N2		33683565
Caenorhabditis elegans	6.25	umol/L							Unclear	N2		33683565
Caenorhabditis elegans	3.13	umol/L			8.7				S	N2		33683565	Active
Caenorhabditis elegans	6.25	umol/L			14.9				S	N2		33683565	Active
Caenorhabditis elegans	12.5	umol/L			21				S	N2		33683565	Active

Experimental Data Visualization

Nobiletin

Statistics Data

Nobiletin

Species	Lifespan Change(AVG/MED%)	Lifespan Change(MAX%)	Count Reference	Count Data point
Caenorhabditis elegans	21		1	6

Statistics Data Visualization

Nobiletin