Compound Summary
Compound Information
Pirenzepine dihydrochloride
Compound Name: | Pirenzepine dihydrochloride |
Compound CID: | 71405 |
Synonyms: | Pirenzepine dihydrochloride 29868-97-1 Pirenzepine hydrochloride Pirenzepine HCl Tabe More... |
Iupac Name: | 11-[2-(4-methylpiperazin-1-yl)acetyl]-5H-pyrido[2,3-b][1,4]benzodiazepin-6-one;dihydrochloride |
InChI: | InChI=1S/C19H21N5O2.2ClH/c1-22-9-11-23(12-10-22)13-17(25)24-16-7-3-2-5-14(16)19(26)21-15-6-4-8-20-18(15)24;;/h2-8H,9-13H2,1H3,(H,21,26);2*1H |
InChIKey: | FFNMBRCFFADNAO-UHFFFAOYSA-N |
Canonical Smiles: | CN1CCN(CC1)CC(=O)N2C3=CC=CC=C3C(=O)NC4=C2N=CC=C4.Cl.Cl |
Isomeric Smiles: | CN1CCN(CC1)CC(=O)N2C3=CC=CC=C3C(=O)NC4=C2N=CC=C4.Cl.Cl |
Molecular Weight: | 424.3 |
Molecular Formula: | C19H23Cl2N5O2 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
Pirenzepine dihydrochloride
Molecular Weight: | 424.3 |
Molecular Formula: | C19H23Cl2N5O2 |
Hydrogen Bond Donor Count: | 3 |
Hydrogen Bond Acceptor Count: | 5 |
Rotatable Bond Count: | 2 |
Heavy Atom Count: | 28 |
Complexity: | 534 |
Synonyms
Pirenzepine dihydrochloride
| Pirenzepine dihydrochloride | Pirenzepine dihydrochloride |
|---|---|
Pirenzepine dihydrochloride |
29868-97-1 |
Pirenzepine hydrochloride |
Pirenzepine HCl |
Tabe |
Pirenzepine 2HCl |
Bisvanil |
Gastrozepin |
Pirenzepine (dihydrochloride) |
Pirenzepinehydrochloride |
LS519 |
UNII-10YM403FLS |
Pirenzepine, Dihydrochloride |
10YM403FLS |
11-2-(4-methylpiperazin-1-yl)acetyl-5H-pyrido2,3-b1,4benzodiazepin-6-one;dihydrochloride |
Leblon |
Maghen |
29868-97-1 (2HCl) |
5,11-Dihydro-11-((4-methyl-1-piperazinyl)acetyl)-6H-pyrido(2,3-b)(1,4)benzodiazepin-6-one dihydrochloride |
5,11-Dihydro-11-(4-methyl-1-piperazinyl)acetyl-6H-pyrido2,3-b1,4benzodiazepin-6-one dihydrochloride |
LS 519 dihydrochloride |
CHEBI:32014 |
11-(2-(4-methylpiperazin-1-yl)acetyl)-5H-benzoepyrido3,2-b1,4diazepin-6(11H)-one dihydrochloride |
LS 519 cl2 |
LS 519Cl2 |
SR-01000000220 |
EINECS 249-907-5 |
Pirenzepine hydrochloride USAN:JAN |
Prestwick_400 |
5,11-Dihydro-11- |
SCHEMBL41704 |
6,11-Dihydro-11-((4-methyl-1-piperazinyl)acetyl)-5H-pyrido(2,3-b)(1,4)benzodiazepin-6-on dihydrochlorid |
SPECTRUM1501138 |
C19H21N5O2.2HCl |
CHEMBL1531864 |
DTXSID50952328 |
Pirenzepine hydrochloride (USAN) |
HMS1568I20 |
HMS1921J05 |
BCP12435 |
Tox21_500962 |
CCG-38974 |
LS 519 |
MFCD00055214 |
s3662 |
AKOS024456369 |
CS-6975 |
LP00962 |
LS 519 C12 |
NSC 757846 |
NCGC00094263-01 |
NCGC00094263-02 |
NCGC00094263-03 |
NCGC00261647-01 |
5,11-Dihydro-11-((4-methylpiperazin-1-yl)acetyl)-6H-pyrido(2,3-b)(1,4)benzodiazepin-6-one dihydrochloride |
6H-Pyrido(2,3-b)(1,4)benzodiazepin-6-one, 5,11-dihydro-11-((4-methyl-1-piperazinyl)acetyl)-, dihydrochloride |
AS-15182 |
HY-17037 |
O383 |
DB-047664 |
B6582 |
EU-0100962 |
FT-0619757 |
A51065 |
D01297 |
P 7412 |
868P971 |
J-017673 |
Pirenzepine dihydrochloride, >=98% (TLC), powder |
SR-01000000220-2 |
SR-01000000220-4 |
SR-01000000220-7 |
Q27114749 |
(4-methyl-1-piperazinyl)acetyl-6H-pyrido2,3-b1,4benzodiazepin-6-one dihydrochloride |
11-2-(4-METHYL-1-PIPERAZINYL)-1-OXOETHYL-5H-PYRIDO2,3-B1,4BENZODIAZEPIN-6-ONE HYDRATE HCL |
Experimental Data
Pirenzepine dihydrochloride
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33 | umol/L | 4 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
Pirenzepine dihydrochloride
Statistics Data
Pirenzepine dihydrochloride
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 4 | 1 | 1 |
Statistics Data Visualization
Pirenzepine dihydrochloride
