Compound Summary
Compound Information
guanfacine hydrochloride
Compound Name: | guanfacine hydrochloride |
Compound CID: | 71401 |
Synonyms: | guanfacine hydrochloride 29110-48-3 GUANFACINE HCL Tenex Intuniv More... |
Iupac Name: | N-(diaminomethylidene)-2-(2,6-dichlorophenyl)acetamide;hydrochloride |
InChI: | InChI=1S/C9H9Cl2N3O.ClH/c10-6-2-1-3-7(11)5(6)4-8(15)14-9(12)13;/h1-3H,4H2,(H4,12,13,14,15);1H |
InChIKey: | DGFYECXYGUIODH-UHFFFAOYSA-N |
Canonical Smiles: | C1=CC(=C(C(=C1)Cl)CC(=O)N=C(N)N)Cl.Cl |
Isomeric Smiles: | C1=CC(=C(C(=C1)Cl)CC(=O)N=C(N)N)Cl.Cl |
Molecular Weight: | 282.5 |
Molecular Formula: | C9H10Cl3N3O |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
guanfacine hydrochloride
Molecular Weight: | 282.5 |
Molecular Formula: | C9H10Cl3N3O |
Hydrogen Bond Donor Count: | 3 |
Hydrogen Bond Acceptor Count: | 1 |
Rotatable Bond Count: | 2 |
Heavy Atom Count: | 16 |
Complexity: | 256 |
Synonyms
guanfacine hydrochloride
| guanfacine hydrochloride | guanfacine hydrochloride |
|---|---|
guanfacine hydrochloride |
29110-48-3 |
GUANFACINE HCL |
Tenex |
Intuniv |
Guanfacine (hydrochloride) |
Estulic |
N-Carbamimidoyl-2-(2,6-dichlorophenyl)acetamide hydrochloride |
29520-14-7 |
BS 100-141 |
N-(Aminoiminomethyl)-2,6-dichlorobenzeneacetamide hydrochloride |
N-Amidino-2-(2,6-dichlorophenyl)acetamide hydrochloride |
UNII-PML56A160O |
SPD503 |
SPD 503 |
MLS000069745 |
PML56A160O |
BS-100-141 |
MFCD00798230 |
SMR000058453 |
29110-48-3 (HCl) |
DSSTox_CID_25157 |
DSSTox_RID_80708 |
DSSTox_GSID_45157 |
Connexyn |
LON 798 |
CAS-29520-14-7 |
GUANFACINEHCL |
Tenex (TN) |
SR-01000075893 |
NCGC00015469-05 |
N-Amidino-2-(2,6-dichlorophenyl)acetamide monohydrochloride |
EINECS 249-443-3 |
N-(Aminoiminomethyl)-2,6-dichlorophenylacetamide monohydrochloride |
C9H10Cl3N3O |
SPD-503 |
Benzeneacetamide, N-(aminoiminomethyl)-2,6-dichloro-, monohydrochloride |
Prestwick_740 |
Guanfacine hydrochloride (JAN/USP) |
Intuniv (TN) |
Guanfacine hydrochloride USAN:USP:JAN |
Opera_ID_1928 |
N-(diaminomethylidene)-2-(2,6-dichlorophenyl)acetamide hydrochloride |
Benzeneacetamide, N-(aminoiminomethyl)-2,6-dichloro-, hydrochloride (1:1) |
G 1043 |
N (Aminoiminomethyl)-2,6-dichlorobenzeneacetamide |
SCHEMBL41681 |
MLS001077329 |
MLS002222252 |
(2,6-Dichlorophenyl)acetylguanidine Hydrochloride |
CHEBI:5559 |
CHEMBL1200494 |
DTXSID2045157 |
SCHEMBL15603414 |
HMS1569C19 |
HMS3747E15 |
Pharmakon1600-01505435 |
BCP21710 |
N-(aminoiminomethyl)-2,6-dichloro-benzeneacetamide hydrochloride |
Tox21_110159 |
Tox21_500519 |
N-(diaminomethylidene)-2-(2,6-dichlorophenyl)acetamide;hydrochloride |
NSC759121 |
s4693 |
AKOS015966858 |
AKOS030242245 |
Tox21_110159_1 |
CCG-213439 |
CCG-220339 |
CS-1254 |
LP00519 |
NSC-759121 |
NCGC00015469-09 |
NCGC00093914-01 |
NCGC00093914-02 |
NCGC00180965-01 |
NCGC00261204-01 |
AS-12253 |
HY-17416 |
Guanfacine hydrochloride, >=98% (HPLC) |
AB0011596 |
BS100-141 |
DB-047525 |
EU-0100519 |
FT-0630546 |
FT-0698181 |
G0414 |
D00606 |
T72238 |
A826918 |
J-017395 |
S-877503 |
SR-01000075893-1 |
SR-01000075893-3 |
SR-01000075893-6 |
Q27286641 |
N-Carbamimidoyl-2-(2,6-dichlorophenyl)-acetamide hydrochloride |
Guanfacine hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material |
Guanfacine hydrochloride, United States Pharmacopeia (USP) Reference Standard |
N-bis(azanyl)methylidene-2-2,6-bis(chloranyl)phenylethanamide hydrochloride |
N-(Aminoiminomethyl)-2,6-dichlorobenzeneacetamide Hydrochloride / N-Amidino-2-(2,6-dichlorophenyl)acetamide Hydrochloride |
Experimental Data
guanfacine hydrochloride
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33 | umol/L | 15 | S | N2 | 33683565 | Active | ||||||
| Caenorhabditis elegans | 13 | umol/L | 15 | S | N2 | 24134630 | Active |
Experimental Data Visualization
guanfacine hydrochloride
Statistics Data
guanfacine hydrochloride
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 15 | 2 | 2 |
Statistics Data Visualization
guanfacine hydrochloride
