Compound Summary
Compound Information
Prazosin hydrochloride
Compound Name: | Prazosin hydrochloride |
Compound CID: | 68546 |
Synonyms: | Prazosin hydrochloride 19237-84-4 Prazosin HCl Minipress Vasoflex More... |
Iupac Name: | [4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-(furan-2-yl)methanone;hydrochloride |
InChI: | InChI=1S/C19H21N5O4.ClH/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14;/h3-4,9-11H,5-8H2,1-2H3,(H2,20,21,22);1H |
InChIKey: | WFXFYZULCQKPIP-UHFFFAOYSA-N |
Canonical Smiles: | COC1=C(C=C2C(=C1)C(=NC(=N2)N3CCN(CC3)C(=O)C4=CC=CO4)N)OC.Cl |
Isomeric Smiles: | COC1=C(C=C2C(=C1)C(=NC(=N2)N3CCN(CC3)C(=O)C4=CC=CO4)N)OC.Cl |
Molecular Weight: | 419.9 |
Molecular Formula: | C19H22ClN5O4 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
Prazosin hydrochloride
Molecular Weight: | 419.9 |
Molecular Formula: | C19H22ClN5O4 |
Hydrogen Bond Donor Count: | 2 |
Hydrogen Bond Acceptor Count: | 8 |
Rotatable Bond Count: | 4 |
Heavy Atom Count: | 29 |
Complexity: | 544 |
Synonyms
Prazosin hydrochloride
| Prazosin hydrochloride | Prazosin hydrochloride |
|---|---|
Prazosin hydrochloride |
19237-84-4 |
Prazosin HCl |
Minipress |
Vasoflex |
Peripress |
Furazosin hydrochloride |
Hypovase |
1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-furanylcarbonyl)piperazine hydrochloride |
Prazosin (hydrochloride) |
CP-12299-1 |
C19H21N5O4.HCl |
UNII-X0Z7454B90 |
MFCD00058177 |
1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-furoyl)piperazine monohydrochloride |
(4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl)(furan-2-yl)methanone hydrochloride |
4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl-(furan-2-yl)methanone;hydrochloride |
MLS000028454 |
CP-12,299-1 |
NSC-292810 |
X0Z7454B90 |
Deprazolin |
Hypovasole |
Pratsiol |
Sinetens |
SMR000058384 |
Minipress (TN) |
19237-84-4 (HCl) |
Minipress Xl |
2-(4-(2-Furoyl)piperazin-1-yl)-4-amino-6,7-dimethoxyquinazoline hydrochloride |
2-{4-(furan-2-yl)carbonylpiperazin-1-yl}-6,7-dimethoxyquinazolin-4-amine hydrochloride |
CHEBI:8365 |
HSDB 3298 |
NSC 292810 |
Prazosin clorhidrato Spanish |
prazosine hydrochloride |
SR-01000003052 |
EINECS 242-903-4 |
Pressin and Hypovase |
Prazosin hydrochloride USAN:USP:JAN |
Prazosin hydrochloride; |
Opera_ID_370 |
PRAZOSINHYDROCHLORIDE |
CHEMBL1558 |
Piperazine, 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-furanylcarbonyl)-, monohydrochloride |
Piperazine, 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-furoyl)-, monohydrochloride |
SCHEMBL41257 |
MLS001148201 |
MLS001333696 |
MLS002153280 |
MLS002222304 |
SPECTRUM1500495 |
Prazosin HCl (Furazosin HCl) |
piperazin-1-yl)(furan-2-yl) |
HY-B0193A |
AOB5346 |
DTXSID50172822 |
SYN3017 |
HMS1570N16 |
HMS1920J10 |
Pharmakon1600-01500495 |
BCP13643 |
Prazosin hydrochloride (JP17/USP) |
Tox21_501002 |
AC-699 |
CCG-39227 |
NSC292810 |
NSC757286 |
s1424 |
AKOS015895394 |
AF-0012 |
H37P844 |
LP01002 |
MCULE-7492026178 |
NSC-757286 |
SB17352 |
VA11573 |
Prazosin hydrochloride, >=99% (TLC) |
Quinazoline, 4-amino-6,7-dimethoxy-2-(4-(2-furoyl)piperazin-1-yl)-, hydrochloride |
NCGC00094296-01 |
NCGC00094296-02 |
NCGC00094296-03 |
NCGC00094296-04 |
NCGC00094296-05 |
NCGC00261687-01 |
BA164294 |
H764 |
ST057530 |
AB0013242 |
DB-044795 |
EU-0101002 |
P0938 |
D00609 |
H11453 |
SR-01000003052-2 |
SR-01000003052-8 |
W-107719 |
Q27108060 |
Piperazine,7-dimethoxy-2-quinazolinyl)-4-(2-furoyl)-, monohydrochloride |
Prazosin hydrochloride, European Pharmacopoeia (EP) Reference Standard |
Prazosin hydrochloride, United States Pharmacopeia (USP) Reference Standard |
1-(3-AMINO-6,7-DIMETHOXY-2-QUINAZOLINY)-4-(2-FURANYLCARBONYL)PIPERAZINE |
1-(4-Amino-6,7-dimethoxy-2-quinazol inyl)-4-(2-furanylcarbonyl)piperazine hydrochloride |
4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazinyl 2-furyl ketone, chloride |
Piperazine,7-dimethoxy-2-quinazolinyl)-4-(2-furanylcarbonyl)-, monohydrochloride |
Methanone, 4-(4-amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl-2-furanyl-, hydrochloride (1:1) |
Experimental Data
Prazosin hydrochloride
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33 | umol/L | 6 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
Prazosin hydrochloride
Statistics Data
Prazosin hydrochloride
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 6 | 1 | 1 |
Statistics Data Visualization
Prazosin hydrochloride
