Compound Summary
Compound Information
Trimethobenzamide hydrochloride
Compound Name: | Trimethobenzamide hydrochloride |
Compound CID: | 68385 |
Synonyms: | Trimethobenzamide hydrochloride 554-92-7 Trimethobenzamide HCL Tigan Nauseton More... |
Iupac Name: | N-[[4-[2-(dimethylamino)ethoxy]phenyl]methyl]-3,4,5-trimethoxybenzamide;hydrochloride |
InChI: | InChI=1S/C21H28N2O5.ClH/c1-23(2)10-11-28-17-8-6-15(7-9-17)14-22-21(24)16-12-18(25-3)20(27-5)19(13-16)26-4;/h6-9,12-13H,10-11,14H2,1-5H3,(H,22,24);1H |
InChIKey: | WIIZEEPFHXAUND-UHFFFAOYSA-N |
Canonical Smiles: | CN(C)CCOC1=CC=C(C=C1)CNC(=O)C2=CC(=C(C(=C2)OC)OC)OC.Cl |
Isomeric Smiles: | CN(C)CCOC1=CC=C(C=C1)CNC(=O)C2=CC(=C(C(=C2)OC)OC)OC.Cl |
Molecular Weight: | 424.9 |
Molecular Formula: | C21H29ClN2O5 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
Trimethobenzamide hydrochloride
Molecular Weight: | 424.9 |
Molecular Formula: | C21H29ClN2O5 |
Hydrogen Bond Donor Count: | 2 |
Hydrogen Bond Acceptor Count: | 6 |
Rotatable Bond Count: | 10 |
Heavy Atom Count: | 29 |
Complexity: | 440 |
Synonyms
Trimethobenzamide hydrochloride
| Trimethobenzamide hydrochloride | Trimethobenzamide hydrochloride |
|---|---|
Trimethobenzamide hydrochloride |
554-92-7 |
Trimethobenzamide HCL |
Tigan |
Nauseton |
Ametik hydrochloride |
Ro 2-9578 |
N-(4-(2-(Dimethylamino)ethoxy)benzyl)-3,4,5-trimethoxybenzamide hydrochloride |
UNII-WDQ5P1SX7Q |
Tribenzagan Hydrochloride |
WDQ5P1SX7Q |
Trimethobenzamide hydrochloride USP |
NSC-37882 |
N-4-2-(dimethylamino)ethoxyphenylmethyl-3,4,5-trimethoxybenzamide;hydrochloride |
554-92-7 (HCl) |
Poligerim |
Tebamide |
Ibikin |
Anaus |
Ticon |
DSSTox_CID_27754 |
DSSTox_RID_82531 |
DSSTox_GSID_47774 |
T-Gen |
Trimethobenzamide hydrochloride (USP) |
N-4-2-(Dimethylamino)ethoxybenzyl-3,4,5-trimethoxybenzamide Hydrochloride |
N-{4-(2-dimethylaminoethoxy)phenylmethyl}-3,4,5-trimethoxy-benzamide hydrochloride |
NCGC00016509-01 |
TRIMETHOBENZAMIDEHYDROCHLORIDE |
CAS-554-92-7 |
EINECS 209-075-6 |
NSC 37882 |
N-({4-2-(dimethylamino)ethoxyphenyl}methyl)(3,4,5-trimethoxyphenyl)carboxami de, chloride |
Prestwick_526 |
4-(2-Dimethylaminoethoxy)-N-(3,4,5-trimethoxybenzoyl)benzylamine hydrochloride |
N-(p-(2-(Dimethylamino)ethoxy)benzyl)-3,4,5-trimethoxybenzamide hydrochloride |
Benzamide, N-((4-(2-(dimethylamino)ethoxy)phenyl)methyl)-3,4,5-trimethoxy-, monohydrochloride |
N-(p-(2-(Dimethylamino)ethoxy)benzyl)-3,4,5-trimethoxybenzamide monohydrochloride |
SCHEMBL41339 |
MLS002154193 |
SPECTRUM1500594 |
CHEMBL1200887 |
DTXSID7047774 |
HMS1568O21 |
HMS1921G21 |
Pharmakon1600-01500594 |
NSC37882 |
Tox21_110465 |
CCG-40276 |
HY-12751A |
MFCD00057999 |
NSC757359 |
s5483 |
SBB058189 |
AKOS022172835 |
Tox21_110465_1 |
CS-7696 |
MCULE-6632962832 |
NSC-757359 |
Benzamide, N-(p-(2-(dimethylamino)ethoxy)benzyl)-3,4,5-trimethoxy-, hydrochloride |
Benzamide,N-4-2-(dimethylamino)ethoxyphenylmethyl-3,4,5-trimethoxy-,monohydrochloride |
NCGC00016509-06 |
NCGC00094803-01 |
NCGC00094803-02 |
Benzamide,4,5-trimethoxy-, hydrochloride |
BS-17063 |
SMR001233483 |
Benzamide,4,5-trimethoxy-, monohydrochloride |
FT-0736653 |
ST51015132 |
T3525 |
V1615 |
C75602 |
D02733 |
WLN: 1OR BO1 CO1 EVM1R DO2N1&1 &GH |
554T927 |
A870178 |
SR-05000001733-3 |
Q27292581 |
N-p-2-(Dimethylamino)ethoxybenzyl-3,5-trimethoxybenzamide hydrochloride |
4-(2-Dimethylamino)ethoxy-N-(3,5-trimethoxybenzoyl)benzylamine hydrochloride |
Benzamide, N-(p-(2-(dimethylamino)ethoxy)benzyl)-3,4,5-trimethoxy-, monohydrochloride (8CI) |
Experimental Data
Trimethobenzamide hydrochloride
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Drosophila melanogaster | 200 | umol/L | 50.43 | 50.89 | 0.9163 | NS | MALES | 33008901 | Inactive | ||||
| Drosophila melanogaster | 20 | umol/L | 61.06 | 59.75 | -2.138 | NS | FEMALES | 33008901 | Inactive |
Experimental Data Visualization
Trimethobenzamide hydrochloride
Statistics Data
Trimethobenzamide hydrochloride
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Drosophila melanogaster | 0.9163 | 1 | 2 |
Statistics Data Visualization
Trimethobenzamide hydrochloride
