Compound Summary
Compound Information
Triflupromazine hydrochloride
Compound Name: | Triflupromazine hydrochloride |
Compound CID: | 66069 |
Synonyms: | Triflupromazine hydrochloride 1098-60-8 Flumazin Fluorofen Neoprin More... |
Iupac Name: | N,N-dimethyl-3-[2-(trifluoromethyl)phenothiazin-10-yl]propan-1-amine;hydrochloride |
InChI: | InChI=1S/C18H19F3N2S.ClH/c1-22(2)10-5-11-23-14-6-3-4-7-16(14)24-17-9-8-13(12-15(17)23)18(19,20)21;/h3-4,6-9,12H,5,10-11H2,1-2H3;1H |
InChIKey: | FTNWXGFYRHWUKG-UHFFFAOYSA-N |
Canonical Smiles: | CN(C)CCCN1C2=CC=CC=C2SC3=C1C=C(C=C3)C(F)(F)F.Cl |
Isomeric Smiles: | CN(C)CCCN1C2=CC=CC=C2SC3=C1C=C(C=C3)C(F)(F)F.Cl |
Molecular Weight: | 388.9 |
Molecular Formula: | C18H20ClF3N2S |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
Triflupromazine hydrochloride
Molecular Weight: | 388.9 |
Molecular Formula: | C18H20ClF3N2S |
Hydrogen Bond Donor Count: | 1 |
Hydrogen Bond Acceptor Count: | 6 |
Rotatable Bond Count: | 4 |
Heavy Atom Count: | 25 |
Complexity: | 416 |
Synonyms
Triflupromazine hydrochloride
| Triflupromazine hydrochloride | Triflupromazine hydrochloride |
|---|---|
Triflupromazine hydrochloride |
1098-60-8 |
Flumazin |
Fluorofen |
Neoprin |
Siquil |
Nivoman |
Triflupromazine HCl |
Triflupromazine (hydrochloride) |
Psyquil |
Vesprin hydrochloride |
Triflupromazine monohydrochloride |
Trifluopromazine hydrochloride |
Fluopromazine monohydrochloride |
UNII-9E75N4A5HM |
MC 4703 |
MLS000069672 |
9E75N4A5HM |
N,N-dimethyl-3-2-(trifluoromethyl)phenothiazin-10-ylpropan-1-amine;hydrochloride |
NCGC00094410-02 |
SMR000058517 |
Vesprin (TN) |
DSSTox_CID_25804 |
DSSTox_RID_81142 |
DSSTox_GSID_45804 |
10-(3-(Dimethylamino)propyl)-2-(trifluoromethyl)phenothiazine monohydrochloride |
10-(3-Dimethylaminopropyl)-2-(trifluoromethyl)phenothiazine hydrochloride |
CHEBI:9712 |
N,N-dimethyl-2-(trifluoromethyl)-10H-phenothiazine-10-propanamine, monohydrochloride |
NSC14959 |
NSC17473 |
WLN: T C666 BN ISJ B3N1&1 EXFFF |
SR-01000000224 |
EINECS 214-149-6 |
Trifluopromazine hydrochloride (VAN) |
CAS-1098-60-8 |
NSC 14959 |
NSC 17473 |
C18H19F3N2S.ClH |
SR-01000000224-4 |
10-3-(Dimethylamino)propyl-2-(trifluoromethyl)phenothiazine hydrochloride |
dimethyl{3-2-(trifluoromethyl)phenothiazin-10-ylpropyl}amine, chloride |
10H-Phenothiazine-10-propanamine,N-dimethyl-2-(trifluoromethyl)-, monohydrochloride |
N,N-dimethyl-3-(2-(trifluoromethyl)-10H-phenothiazin-10-yl)propan-1-amine hydrochloride |
N,N-dimethyl-3-2-(trifluoromethyl)-10H-phenothiazin-10-ylpropan-1-amine hydrochloride |
Prestwick_893 |
Triflupromazine hydrochloride USP:JAN |
Opera_ID_486 |
Fluopromazine hydrochloride |
10H-Phenothiazine-10-propanamine, N,N-dimethyl-2-(trifluoromethyl)-, monohydrochloride |
MLS001148408 |
MLS002222277 |
SCHEMBL317144 |
SPECTRUM1503118 |
REGID_for_CID_66069 |
CHEMBL1201102 |
DTXSID8045804 |
HMS1568K07 |
HMS1922G15 |
Pharmakon1600-01503118 |
HY-B0909 |
Tox21_111276 |
Tox21_501146 |
2767AH |
MFCD00058103 |
NSC-14959 |
NSC-17473 |
NSC758387 |
s5565 |
SBB058191 |
AKOS024288004 |
Tox21_111276_1 |
CCG-213116 |
LP01146 |
MCULE-4776607695 |
NSC-758387 |
Phenothiazine, 10-(3-(dimethylamino)propyl)-2-(trifluoromethyl)-, monohydrochloride |
NCGC00016012-12 |
NCGC00094410-01 |
NCGC00094410-03 |
NCGC00094410-04 |
NCGC00094410-05 |
NCGC00261831-01 |
Triflupromazine hydrochloride (JAN/USP) |
BS-25525 |
EU-0101146 |
FT-0736671 |
ST51015135 |
SW197014-3 |
T3389 |
C71345 |
D00800 |
T 2896 |
J-002339 |
SR-01000000224-2 |
SR-01000000224-8 |
Q27108479 |
Z1642388275 |
Triflupromazine Hydrochloride 1.0 mg/ml in Methanol (as free base) |
Triflupromazine hydrochloride, VETRANAL(TM), analytical standard |
10-3-(Dimethylamino)-1-propyl-2-(trifluoromethyl)phenothiazine Hydrochloride |
dimethyl({3-2-(trifluoromethyl)-10H-phenothiazin-10-ylpropyl})amine hydrochloride |
Phenothiazine, 10-(3-dimethylaminopropyl)-2-(trifluoromethyl)-, hydrochloride |
Triflupromazine hydrochloride, United States Pharmacopeia (USP) Reference Standard |
Experimental Data
Triflupromazine hydrochloride
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Drosophila melanogaster | 20 | umol/L | 46.24 | 48.53 | 4.97 | S | FEMALES | 33008901 | Active | ||||
| Drosophila melanogaster | 200 | umol/L | 46.64 | 47.28 | 1.381 | NS | MALES | 33008901 | Inactive | ||||
| Caenorhabditis elegans | 33 | umol/L | -34 | NS | N2 | 24134630 | Inactive | ||||||
| Caenorhabditis elegans | 10 | umol/L | 17.09 | 13.22 | -22.64 | NS | N2 | 33008901 | Inactive | ||||
| Caenorhabditis elegans | 100 | umol/L | 15.16 | 9.316 | -38.53 | NS | N2 | 33008901 | Inactive |
Experimental Data Visualization
Triflupromazine hydrochloride
Statistics Data
Triflupromazine hydrochloride
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -22.64 | 2 | 3 | |
| Drosophila melanogaster | 4.97 | 1 | 2 |
Statistics Data Visualization
Triflupromazine hydrochloride
