Compound Summary
Compound Information
SB 218795
Compound Name: | SB 218795 |
Compound CID: | 6604858 |
Synonyms: | SB 218795 174635-53-1 SB-218795 Sb218795 CHEMBL9843 More... |
Iupac Name: | methyl (2R)-2-phenyl-2-[(2-phenylquinoline-4-carbonyl)amino]acetate |
InChI: | InChI=1S/C25H20N2O3/c1-30-25(29)23(18-12-6-3-7-13-18)27-24(28)20-16-22(17-10-4-2-5-11-17)26-21-15-9-8-14-19(20)21/h2-16,23H,1H3,(H,27,28)/t23-/m1/s1 |
InChIKey: | IUMQXQJZIHWLIN-HSZRJFAPSA-N |
Canonical Smiles: | COC(=O)C(C1=CC=CC=C1)NC(=O)C2=CC(=NC3=CC=CC=C32)C4=CC=CC=C4 |
Isomeric Smiles: | COC(=O)[C@@H](C1=CC=CC=C1)NC(=O)C2=CC(=NC3=CC=CC=C32)C4=CC=CC=C4 |
Molecular Weight: | 396.4 |
Molecular Formula: | C25H20N2O3 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
SB 218795
Molecular Weight: | 396.4 |
Molecular Formula: | C25H20N2O3 |
Hydrogen Bond Donor Count: | 1 |
Hydrogen Bond Acceptor Count: | 4 |
Rotatable Bond Count: | 6 |
Heavy Atom Count: | 30 |
Complexity: | 583 |
Synonyms
SB 218795
| SB 218795 | SB 218795 |
|---|---|
SB 218795 |
174635-53-1 |
SB-218795 |
Sb218795 |
CHEMBL9843 |
methyl (2R)-2-phenyl-2-(2-phenylquinoline-4-carbonyl)aminoacetate |
Benzeneacetic acid, alpha-(((2-phenyl-4-quinolinyl)carbonyl)amino)-, methyl ester, (alphaR)- |
Methyl (2R)-phenyl{(2-phenyl-4-quinolinyl)carbonylamino}acetate |
Benzeneacetic acid, alpha-(2-phenyl-4-quinolinyl)carbonylamino-, methyl ester, (alphaR)- |
SB 218795R |
Tocris-1376 |
Lopac0_000624 |
MLS000862187 |
GTPL5764 |
SCHEMBL4459316 |
CHEBI:93066 |
DTXSID80938539 |
HMS2231I18 |
HMS3261N10 |
HMS3267B22 |
HMS3412K06 |
HMS3676K06 |
ZINC601874 |
Tox21_500624 |
BDBM50051289 |
AKOS024456559 |
CCG-204712 |
LP00624 |
SDCCGSBI-0050605.P002 |
NCGC00025131-01 |
NCGC00025131-02 |
NCGC00025131-03 |
NCGC00025131-04 |
NCGC00261309-01 |
SMR000326950 |
EU-0100624 |
S 8817 |
SR-01000075910 |
SR-01000597578 |
J-011022 |
SR-01000075910-1 |
SR-01000597578-1 |
BRD-K61097567-001-03-6 |
Q27088704 |
(-)-(R)-N-(alpha-Methoxycarbonylbenzyl)-2-phenylquinoline-4-carboxamide |
(R)-2-Phenyl-4-quinolinyl)carbonylamino-methyl ester benzeneacetic acid |
N-(2-Methoxy-2-oxo-1-phenylethyl)-2-phenylquinoline-4-carboximidic acid |
(R)-Phenyl-(2-phenyl-quinoline-4-carbonyl)-amino-acetic acid methyl ester |
Experimental Data
SB 218795
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33 | umol/L | -3 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
SB 218795
Statistics Data
SB 218795
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -3 | 1 | 1 |
Statistics Data Visualization
SB 218795
