Compound Summary
Compound Information
MRS 1754
Compound Name: | MRS 1754 |
Compound CID: | 6603931 |
Synonyms: | MRS 1754 264622-58-4 MRS1754 MRS-1754 UNII-7E435V2DAH More... |
Iupac Name: | N-(4-cyanophenyl)-2-[4-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)phenoxy]acetamide |
InChI: | InChI=1S/C26H26N6O4/c1-3-13-31-24-22(25(34)32(14-4-2)26(31)35)29-23(30-24)18-7-11-20(12-8-18)36-16-21(33)28-19-9-5-17(15-27)6-10-19/h5-12H,3-4,13-14,16H2,1-2H3,(H,28,33)(H,29,30) |
InChIKey: | AJBBEYXFRYFVNM-UHFFFAOYSA-N |
Canonical Smiles: | CCCN1C2=C(C(=O)N(C1=O)CCC)NC(=N2)C3=CC=C(C=C3)OCC(=O)NC4=CC=C(C=C4)C#N |
Isomeric Smiles: | CCCN1C2=C(C(=O)N(C1=O)CCC)NC(=N2)C3=CC=C(C=C3)OCC(=O)NC4=CC=C(C=C4)C#N |
Molecular Weight: | 486.5 |
Molecular Formula: | C26H26N6O4 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
MRS 1754
Molecular Weight: | 486.5 |
Molecular Formula: | C26H26N6O4 |
Hydrogen Bond Donor Count: | 2 |
Hydrogen Bond Acceptor Count: | 6 |
Rotatable Bond Count: | 9 |
Heavy Atom Count: | 36 |
Complexity: | 843 |
Synonyms
MRS 1754
| MRS 1754 | MRS 1754 |
|---|---|
MRS 1754 |
264622-58-4 |
MRS1754 |
MRS-1754 |
UNII-7E435V2DAH |
7E435V2DAH |
CHEMBL273807 |
N-(4-cyanophenyl)-2-4-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)phenoxyacetamide |
N-(4-Cyanophenyl)-2-(4-(2,6-dioxo-1,3-dipropyl-2,3,6,9-tetrahydro-1H-purin-8-yl)phenoxy)acetamide |
N-(4-Cyanophenyl)-2-4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-dipropyl-1H-purin-8-yl)phenoxy-acetamide |
N-(4-cyanophenyl)-2-(4-(2,6-dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)phenoxy)acetamide |
3HMRS1754 |
3H-MRS1754 |
NCGC00015689-01 |
Lopac-M-6316 |
Lopac0_000729 |
GTPL449 |
GTPL453 |
MLS002153324 |
SCHEMBL1222380 |
CHEBI:93269 |
AOB5542 |
DTXSID80424967 |
HMS2230A06 |
HMS3268F13 |
HMS3373J21 |
HMS3742I17 |
BCP31360 |
ZINC4475274 |
BDBM50086170 |
s6693 |
AKOS024457276 |
CCG-204814 |
EX-3306 |
MRS-1754; MRS 1754 |
NCGC00015689-02 |
NCGC00015689-03 |
NCGC00015689-04 |
NCGC00094075-01 |
NCGC00094075-02 |
NCGC00094075-03 |
HY-14121 |
SMR001230737 |
B7173 |
CS-0003210 |
EU-0100729 |
M 6316 |
L000415 |
SR-01000076213 |
J-016440 |
SR-01000076213-1 |
BRD-K72024482-001-01-3 |
Q27087766 |
8-4-((4-Cyanophenyl)carbamoylmethyl)oxyphenyl-1,3-di(n-propyl)xanthine |
(4-Cyano-phenyl)-carbamic acid 4-(2,6-dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-phenyl ester |
Acetamide, N-(4-cyanophenyl)-2-(4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-dipropyl-1H-purin-8-yl)phenoxy)- |
N-(4-Cyano-phenyl)-2-4-(2,6-dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-phenoxy-acetamide |
N-(4-Cyano-phenyl)-2-4-(2,6-dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-phenoxy-acetamide(MRS-1754) |
Experimental Data
MRS 1754
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33 | umol/L | 4 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
MRS 1754
Statistics Data
MRS 1754
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 4 | 1 | 1 |
Statistics Data Visualization
MRS 1754
